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All Journal Dentika Dental Journal Journal of Dentistry Indonesia ODONTO Dental Journal Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dentistry Journal of Case Reports in Dental Medicine Majalah Sainstekes ASEAN Journal of Community Engagement Cakradonya Dental Journal Odonto dental journal

Febrina Rahmayanti

Department Of Oral Medicine, Faculty Of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia

Author-ID : 356396

Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Other

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Complication risks of invasive dental procedures in HIV/AIDS patients Cahyati, Miftakhul; Rahmayanti, Febrina
Padjadjaran Journal of Dentistry Vol 20, No 3 (2008): November
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

A total number of people living with HIV reached since it was first reported. Indonesia is on the brink of rapidly worsening AIDS epidemic. Oral health was a frequent problem among HIV-infected person. Opportunistic oral lesions and infections were often one of the first manifestations of HIV. The aim of this literature review was to discuss complication risks and management undergoing invasive dental procedures. Thereby, dentists have been expected to increase awareness of dental treatment needs for HIV-infected patients by pay attention to applied standard procedure. The complications of HIV-infected patients were reported minor, self-limiting, non-life threatening and readily treated. Treatment planning for the patient with HIV follows the same sequences as with other patients priorities are to assuage pain, restore function, prevent further disease and consider esthetic results. We concluded that no different complication risks between HIV-infected and non-infected. Dentists can provide care for HIV-infected patients with assessing the current immunosuppression stage, intake systemic medications, opportunistic infection potential and minimize contagion possibility to dental care professional or other patients.

SALIVARY PROFILE AND IDENTIFICATION OF EXISTING CANDIDA sp OF AN INSTITUTIONALIZED ELDERLY POPULATION IN JAKARTA: PROFIL SALIVA DAN IDENTIFIKASI KEBERADAAN CANDIDA sp PADA LANSIA DI PANTI JOMPO DI JAKARTA Febrina Rahmayanti; Yuniardini Septorini Wimardhani; Indriasti Wardhany
Dentika: Dental Journal Vol. 17 No. 4 (2013): Dentika Dental Journal
Publisher : TALENTA

Saliva plays an important role to protect oral and dental health, in maintenance oral microflora balance. In elderly, disease, and medications usually influence the saliva. The purpose of this preliminary study was to investigate salivary profile, oral symptoms of dryness, and existing of Candida sp of an institutionalized elderly in Jakarta, Twenty seven (27) elderly (17 men and 10 women) were examined in a cross sectional study. Unstimulated whole saliva was collected for 5 minutes, according to published protocol, and then salivary flow rate and pH were measured. Candida sp were cultured in CHROM agar. The yeasts were counted and identified. Oral symptom or complaints of oral dryness, and burning or itching were recorded with an interview. Data of systemic conditions and medication the used were obtained from the medical record. Eighteen (66.7%) CHROM agar plates were Candida sp positive cultured, and about 61.1% subjectsâ€™ salivary pH were below normal range. Twenty one (77.8%) subjects had oral symptom and complain about oral dryness, even thought the salivary flow rate were in normal range. In this study, C.albicans is not the most frequently found colonized. About 72% were identified not C.albicans. This study suggests that, in elderly which salivary pH was below normal range have greater opportunistic infected by Candida sp. It can be concluded that, the result did not confirm a significant difference between subjectsâ€™ data and salivary profile concentration. The mycological finding Candida albicans is not the most frequently found colonized in this elderly population. Further study which lagger elderly population and might give deeper insights of salivary profile in this population.

RELATIONSHIP OF SALIVARY PEROXIDASE ACTIVITY TO CD4+ LEVEL IN HIV/AIDS PATIENTS: HUBUNGAN AKTIVITAS PEROKSIDASE SALIVA TERHADAP TINGKAT CD4 PASIEN HIV/AIDS Febrina Rahmayanti; Yuniardini S Wimardhani
Dentika: Dental Journal Vol. 16 No. 1 (2011): Dentika Dental Journal
Publisher : TALENTA

Human whole saliva contains peroxidases (human peroxidase and myeloperoxidase) which are part of the innate host defence mechanism in oral cavity. The primary function is to catalyse the oxidation of thyocyanate, in the presence of hydrogen peroxidase, that resulting in the end product of wide antimicrobial activity. Patient with HIV/AIDS is often decreased in salivary flow rate, and this condition may also change the salivary composisition. These changes are contributed in oral lesions of HIV/AIDS patients. The aim of this study was to evaluate the salivary peroxidase activities of HIV/AIDS patients. The study involved 98 patients with HIV/AIDS of whom 55 were men and 43 were women. Unstimulated whole saliva was collected and all the patients received a complete oral examination. The saliva samples were analysed with Bradford assay (with Bradford reagent) and salivary peroxidase measurement with microplate reader and read at 450 nm wave length. The results showed that the mean concentration of total salivary protein and peroxidase in this study population was 1169Âµg/ml (SDÂ±186.1) and 6.101unit/mg Protein (SDÂ±1.26) respectively. It showed a tendency that the lower the CD4 level, the higher the total protein concentration as well as salivary peroxidase activity, however the difference was not statistically significant (p>0.05). Patientsâ€™ data on age, sex, salivary flow rate and pH did not significantly influencing the total salivary protein concentration as well as the peroxidase activity (p>0.05). This study showed that salivary peroxidase activity have a correlation with the total salivary protein concentration. There was a tendency of higher total protein concentration and salivary peroxidase activity found in patients with lower CD4 counts but in those with more acidic saliva. In conclusion, salivary peroxidase activity have a correlation with the total salivary protein concentration in HIV/AIDS patients.

A Case of Inconspicuous Recurrent Herpes Labialis Mimicking Unilateral Angular Cheilitis Mandasari, Masita; Astuti, Ambar Kusuma; Rahmayanti, Febrina
Journal of Dentistry Indonesia Vol. 25, No. 3
Publisher : UI Scholars Hub

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Recurrent herpes labialis (RHL) is a common manifestation of herpes simplex virus (HSV) reactivation in immunocompetent individuals, whereas angular cheilitis is an inflammatory lesion occurring on one or both lip commissures and is induced by local and/or systemic conditions. We describe a case of RHL eruption on the corner of the mouth, easily mistaken as angular cheilitis. Case Report: A 21-year-old male presented to our dental hospital with a 3 day history of a painful, unilateral lesion on the left corner of his mouth. The lesion featured an erythematous base with a yellowish crust that extended outward. We diagnosed the lesion as RHL. We prescribed chlorhexidine solution and topical acyclovir to be applied onto the lesion. At 2 weeks follow-up, the lesion was resolved. An RHL lesion that erupts on the corner of the mouth may initially resemble angular cheilitis. However, the typical clinical presentation, history of recurrence, and the absence of predisposing factors for other lesions suggested an infection caused by HSV. Conclusion: RHL which occurred at one side of the mouth corner can be similar with unilateral AC. But, detailed history taking and clinical observation led to correct diagnosis and management.

Health-Related Anxiety in the Management of Oral Soreness in an HIVSeropositive Patient Mandasari, Masita; Syarif, Zulvia Oktanida; Rahmayanti, Febrina
Journal of Dentistry Indonesia Vol. 27, No. 1
Publisher : UI Scholars Hub

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The number of people living with HIV (PLHIV) has been increasing since the first known case in the early 1980s. However, PLHIV can also experience comorbidities, such as health anxiety. In the oral cavity, anxiety is often associated with the etiology of parafunctional habits. Anxiety can be measured using self-administered instruments, such as the Hospital Anxiety and Depression Scale (HADS) and Short-Health Anxiety Inventory (SHAI), which is specifically used in the medical setting. Objectives: We are describing a case of HIV positive patient with health anxiety who presented to the oral medicine clinic in our hospital with a complaint of discomfort on his lateral sides of the tongue. Case Report: A 35-year-old male patient came to the oral medicine clinic complaining of discomfort on his tongue, which presented for one week. The patient was alarmed by two bumps seen on the right lateral side of his tongue and soreness on the left lateral side. Nystatin oral suspension was prescribed by a medical doctor but discontinued by the patient. The patient was positive for HIV and took ART routinely. Extraoral and intraoral examinations showed unremarkable findings except slightly enlarged and erythematous foliate papillae on the left lateral side of the tongue. The patient was prescribed an antiseptic mouth rinse. After several days, his symptoms had dissipated. Since the patient reported anxiety regarding his health and HIV status, we asked the patient to complete the HADS and SHAI self-assessment tools to measure his level of anxiety. The patient was shown to have anxiety using the SHAI (total score = 21). Conclusion: Health anxiety is a condition that an individual misinterprets as a benign bodily sensation. The management of this type of patient involves addressing the local predisposing factor of the oral complaint and maintaining oral hygiene, followed by an evaluation of health anxiety for the basis of referral to a psychological expert.

Multiple Oral Ulcerations in a Seizure Patient with Undiagnosed Brain Arteriovenous Malformation Astuti, Ambar Kusuma; Rahmayanti, Febrina
Journal of Dentistry Indonesia Vol. 28, No. 1
Publisher : UI Scholars Hub

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Multiple ulcerations are rarely caused by a traumatic event, but seizures can induce repeated injury to the oral mucosa. A patient with a seizure history possesses a challenge in their dental management. Objective: In order to describe a case of multiple oral ulceration in a post-seizure patient with undiagnosed arteriovenous malformation (AVM) in the left parietal lobe and provide short guidelines for dentists in managing patient with a seizure history. Case report: A 23-years old female had multiple oral ulceration in the right and left buccal mucosa and her tongue. She reported having a seizure attack six days before. The patient never had a history of seizures or recurrent oral ulceration. During the seizure, improper placement of the spoon caused further damage to her oral mucosa. The trigger of her seizure is unknown. Based on the neurological consultation, she had an AVM on the left temporal lobe. In order to relieve pain, mouthwash containing aloe vera, sodium hyaluronate, glycyrhettinic acid, and polyvinylpyrrolidone (PVP) was prescribed. Conclusion: Dentists should be aware that oral mucosal injury can be related to a seizure disorder. A proper history and examination are essential to make an appropriate diagnosis. A safe dental treatment in seizure patients can be delivered accordingly.

Multiple Clinical Findings on The Tongue: Variants of Normal or Pathologic Condition? (A Case Report): Temuan Klinis Multipel pada Lidah: Variasi Normal atau Kondisi Patologis? (Sebuah Laporan Kasus) Alhayu, Yurina; Rahmayanti, Febrina; Astuti, Ambar Kusuma
Dentika: Dental Journal Vol. 24 No. 2 (2021): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/dentika.v24i2.7220

Various normal and pathologic findings might occasionally be found on the tongue and might confuse some patients and clinician due to its atypical presentation. This case report aimed to present a case report of multiple oral findings related to variants of normal and pathological findings on the tongue: geographic tongue, fissured tongue, and central papillary atrophy. A 53-year-old male patient came to Universitas Indonesia Dental Hospital for a dental check-up. Objective examination in the tongue showed depapilated areas surrounded by keratinized lining in the ventral and lateral left and right area of the tongue, multiple fissures in all over the dorsum of the tongue, and an ovoid redness area in the middle of 2/3 posterior dorsum part of the tongue. All those findings were asymptomatic. Those clinical findings were diagnosed as geographic tongue, fissured tongue, and central papillary atrophy. This case presents unique multiple variants of normal and pathological findings in the tongue. It is important to an oral health professional to have knowledge and ability to determine normal anatomy, variants of normal and pathological lesions. Patients should be informed and educated about oral mucosa normal variations and related clinical findings so they would not develop unnecessary anxiety. Keywords: central papillary atrophy, fissured tongue, geographic tongue, normal variations

IDENTIFIKASI FAKTOR RISIKO TERJADINYA KOLONISASI SPESIES CANDIDA DI RONGGA MULUT PADA INDIVIDU SEHAT (PENELITIAN PADA MAHASISWA & MAHASISWI FKG UI) Audiawati Audiawati; Siti Aliyah Pradono; Febrina Rahmayanti
Majalah Sainstekes Vol 2, No 1 (2015): Juni 2015
Publisher : Lembaga Penelitian Universitas YARSI

Introduction : Cases of oral candidiasis are commonly found, both in healthy individuals and immunecompromise patients, however publications of Candida carrier in the oral cavity of healthy population and risk factors for colonization in Indonesia are hardly available. Objective : This study was aimed to analyze the type and number of Candida colonies and identify risk factors in the oral cavity of apparenthly health FKG UI students. Material and methods : the specimens were taken from 195 subjects with oral rinse technique for identification using culture medium CHROMagar® and Sabaraoud dextrose agar. Results and discussion : Candida species were found in the 107 subjects oral cavity (54.87%), being Candida albicans was is the predominant species (52.33%). Some 88 subjects (82.24%) was dominant in the number of colonies less than 400 CFU/ml, while the rest had colony of more than 400 CFU/ml (17.76%). Candida colony grew dominantly in single colony (90.65%), and the others showed multi-species colonies (9.34%). Risk factors identified included age; gender; hormonal; blood type O; denture; orthodontic appliances; unstimulated salivary flow; pH of saliva; smoking, alcohol and oral cleaning habit; and oral health status. By using a statistical Pearson chi-square test, no significant relationship was found between risk factors and number of Candida colonies in the oral cavity p less than 0.05. Conclusion : there was no one single risk factor for Candida colonization, but combination of various risk factors for demographis, local and systemic was observed

Medication intake and its influence on salivary profile of geriatric outpatients in Cipto Mangunkusumo Hospital Yuniardini Septorini Wimardhani; Winanda Annisa; Febrina Rahmayanti
Dental Journal (Majalah Kedokteran Gigi) Vol. 45 No. 3 (2012): September 2012
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: It has been well documented that several diseases or conditions and their related medications could be the risk factors for several ailments found in the oral cavity. Increased usage of medication in elderly could have impact on quality of saliva that affects oral health, eventually cause deterioration in quality of life. Purpose: examine the salivary pH, buffering capacity, stimulated- and unstimulated salivary flow rate profile in elderly using medications. Methods: Seventy-six elderly were consented and agreed to participate in this study. Interview and medical record analysis were performed to get data about their health status, chronic use of medications and complaints related to xerostomia. Collection of unstimulated and stimulated saliva samples were completed in parallel with measurement of salivary pH and buffering capacity. Results: The mean salivary pH was moderately acidic while having low salivary buffering capacity. The mean unstimulated salivary flow rate (USSFR) was 0.24 ± 1.8ml/min and 41of subjects (53%) were classified hyposalivation, while the stimulated salivary flow rate (SSFR) was 0.86 ± 0.49ml/min and 31 (40%) classified hyposalivation. Number of drugs-induced xerostomia intake significantly correlated with the reduction in the USSFR of subjects (p<0.0001), however it was not the case with salivary pH and buffering capacity (p>0.05). It also showed correlation with complaints related to xerostomia. The mean USSFR did not correlate with xerostomia complaints. Conclusion: Medications intake influenced salivary profile and had more effect in changes in xerostomia complaints and salivary quantity than to salivary pH and buffering capacity in Indonesian elderly population.Latar belakang: Telah lama diketahui bahwa beberapa penyakit atau kondisi sistemik dan medikasinya dapat menjadi faktor resiko terjadinya beberapa kelainan dalam rongga mulut. Meningkatnya penggunaan medikasi sistemik pada lansia dapat mempengaruhi kualitas saliva sehingga berpengaruh pada kesehatan mulut yang akhirnya menyebabkan menurunnya kualitas hidup. Tujuan: Mengetahui profil pH saliva, kapasitas dapar, laju aliran saliva terstimulasi (LAST) dan tanpa stimulasi (LASTS) pada lansia yang mendapatkan medikasi sistemik. Metode: Tujuh puluh enam lansia telah menandatangani inform consent dan setuju untuk berpartisipasi. Wawancara dan analsis rekam medis dilakukan untuk mendapatkan data tentang status kesehatan, penggunaan medikasi sistemik jangka panjang dan keluhan xerostomia. Pengumpulan saliva tanpa stimulasi dan terstimulasi dilakukan bersama-sama dengan pengukuran pH dan kapasitas dapar. Hasil: pH saliva subyek adalah berada dalam kelompok asam sedang dengan kapasitas dapar yang rendah. Rerata LASTS adalah 0,24 ± 1,8ml/menit dan 41 subyek (53%) mengalami hiposalivasi, sementara LAST adalah 0,86 ± 0,49ml/menit dan 31 subyek (40%) mengalami hiposalivasi. Jumlah medikasi yang dapat menginduksi xerostomia secara bermakna berhubungan dengan penurunan LASTS (p < 0,0001), namun tidak demikian dengan pH dan kapasitas dapar (p>0,05). Medikasi sistemik juga berhubungan dengan keluhan yang terkait xerostomia. Rerata LASTS tidak berhubungan dengan keluhan xerostomia. Kesimpulan: Medikasi sistemik pada populasi lansia Indonesia mempengaruhi profil saliva dan mempunyai pengaruh yang lebih besar pada keluhan xerostomia dan kuantitas saliva dibandingkan pH dan kapasitas dapar.

PERAWATAN KANDIDIASIS ORAL PADA PASIEN HIV/AIDS (Studi Pustaka) Sri Rezeki; Febrina Rahmayanti
Cakradonya Dental Journal Vol 13, No 1 (2021): Februari 2021
Publisher : FKG Unsyiah

Kandidiasis oral merupakan infeksi jamur oportunistik yang paling sering terjadi pada pasien HIV/AIDS. Terdapat beberapa obat antijamur yang dapat digunakan dalam perawatan kandidiasis oral pada pasien HIV/AIDS, namun pemilihannya tergantung beberapa faktor, seperti perluasan lesi, keparahan penyakit, kondisi asam lambung, level supresi imun, farmakodinamik/farmakokinetik, interaksi obat, resistensi, dan tingkat kepatuhan pasien. Namun, kandidiasis oral refractory dapat terjadi yaitu kegagalan dalam merespon perawatan dengan antijamur. Pada kasus seperti ini, identifikasi Candida dari daerah orofaring dapat membantu membedakan penyebab kegagalan lain secara mikrobiologis. Pasien AIDS diketahui mengalami hypochlorhydria dan peningkatan pH lambung, sehingga berpotensi terjadi penurunan absorpsi dan bioavailabilitas beberapa obat antijamur. Pasien dengan kondisi ini dapat diberikan flukonazol oral karena tidak tergantung pada pH lambung, dapat diabsorpsi dengan cepat, serta memiliki bioavailabilitas tinggi, sehingga flukonazol lebih unggul dibandingkan golongan azol lain dan antijamur topikal seperti nistatin supsensi oral maupun klotrimazol troches. Larutan itrakonazol dan posakonazol dapat dijadikan terapi second-line yang dapat digunakan, selain itu peningkatan imunitas lokal dan sistemik merupakan hal yang penting dalam melawan infeksi Candida. Dengan demikian, berdasarkan tinjauan pustaka flukonazol lebih baik digunakan dalam perawatan kandidiasis oral pada pasien HIV/AIDS.

Co-Authors ., Dadun Alhayu, Yurina Alwin, Wanarani Amatul Firdaus Ramadhan Ambar Kusuma Astuti Anandina Irmagita Soegyanto Andayani, Gitalisa Audiawati Audiawati Bani, Anna Puspitasari Daniel, Hisar Dwiranti, Astari Fitriana, Anis Harini, Melinda Ida Ruwaida, Ida Idris, Mohamad Z. Indrastiti, Ratna K. Indrastiti, Ratna Kumala Indriasti Wardhany Irawati, Yunia Kurniawan, Rico Luh Karunia Wahyuni, Luh Karunia Luzanil, Sonny Tirta Made Susiyanti Mandasari, Masita Matsurah, Qaishum Menaldi, Adhityawarman Menaldi, Sri Linuwih SW Miftakhul Cahyati Priscilia, Florentina Sahid, Muhammad Hidayat Samsul Samsul Siti Aliyah Pradono Sri Rezeki Syarif, Zulvia Oktanida Tri Rahayu Wicaksono, Gunawan Winanda Annisa Yeni Dwi Lestari Yuniardini S Wimardhani Yuniardini S Wimardhani Yuniardini S. Wimardhani, Yuniardini S. Yuniardini Septorini Wimardhani Yuniardini Septorini Wimardhani Yuniardini Septorini Wimardhani

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