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All Journal Journal of Empowerment Community journal of Basic Medical Veterinary Jurnal Ilmu Akuntansi Mulawarman (JIAM)
Gunawan, Aris
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Immunology & microbiology Medicine & Pharmacology Social Sciences Veterinary

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Role of Vitamin D and E as Antioxidants Against Cerebral Endothelial Dysfunction: An In Vivo Study in White Rats (Rattus norvegicus) Sepsis Model Fajri, Fauzan; Fajar, Sukmawan; Hasan, Denny Irmawati; Dimiati, Herlina; Amna, Eka Yunita; Sovira, Nora; Anidar, Anidar; Safri, Mulya; Gunawan, Aris
Journal of Basic Medical Veterinary Vol. 13 No. 2 (2024): Journal of Basic Medical Veterinary, December 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbmv.v13i2.61610

Abstract

Sepsis is a life-threatening condition caused by the body's response to an infection, leading to organ dysfunction. A antioxidants can help neutralize harmful free radicals that cause cellular and tissue damage through oxidative stress. Vitamin D and E are two antioxidants that have been extensively studied for their potential effectiveness. This study aims to evaluate the effectiveness of vitamins D and E in reducing oxidative stress in the cerebral vascular endothelial cells of Wistar mice in a sepsis model. The study follows an experimental design and uses a posttest with a control group. The levels of NO and SOD in 24 sepsis model mice were measured using ELISA, and the cerebral endothelial tissues were examined histopathologically. An ANOVA test was performed, followed by the Post Hoc LSD test. NO and SOD levels decreased in sepsis rats from 66.88 ± 16.59 to 88.77 ± 12.83µmol/L. Sepsis mice given vitamin D and E showed significant results on changes in NO and SOD levels (p<0.05). Based on the histopathological results of necrosis, inflammation, and hemorrhagic cell damage in sepsis rats reached over 50% of the field of view, significantly different from sepsis mice that had been given vitamin D and E. Sepsis mice were given vitamin D and E influenced 96.2% and 98.7% on changes in NO, SOD, and cerebral endothelial dysfunction (p<0.05). These findings imply that vitamins D and E may be beneficial in managing sepsis-induced cerebral endothelial dysfunction, potentially impacting the treatment and outcomes of sepsis patients.
Pengaruh Pemberian Kredit terhadap Pendapatan Pedagang Kecil pada BPR BePeDe Kutai Sejahtera Gunawan, Aris; Asmapane, Set; Kurniawan, Indra Suyoto
Jurnal Ilmu Akuntansi Mulawarman (JIAM) Vol. 4 No. 4 (2019): November
Publisher : Fakultas Ekonomi dan Bisnis Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29264/jiam.v4i4.5758

Abstract

Penelitian ini bertujuan untuk mengetahui  pengaruh pemberian kredit kepada usaha kecil pada BPR BePeDe Kutai Sejahtera terhadap  pendapatan pedagang kecil di kota Samarinda. Metode penelitian yang digunakan adalah metode kualitatif deskriptif. Populasi dalam penelitian ini adalah 98 debitur BPR BePeDe Kutai Sejahtera periode 2016-2018 dan diambil sampel sebanyak 50 debitur. Teknik analisis data dilakukan pengumpulan data serta pemberian kuesioner kepada debitur. Hasil penelitian menunjukkan bahwa Pemberian kredit memberikan pengaruh terhadap pendapatan pedagang kecil. Hal tersebut dibuktikan dengan adanya perbedaan pendapatan pada saat sebelum menerima kredit dan sesudah meneriman kredit.
Pengembangan UMKM Melalui Sosialisasi Pemasaran Berbasis E-Commerce Patimah, Titin; Rahmatulloh, Fauzi; Bakhita Fauzi, Hayya; Ardianti, Zahra; Pradita Sari, Sindi; Azka Karimah, Naila; Gunawan, Aris
Journal of Empowerment Community Vol 8 No 2 (2026): Oktober 2026 (In Press)
Publisher : Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/jec.v8i2.2795

Abstract

MSMEs often face limitations in reaching a wider market. Generally, micro and small business actors have not been adaptive in using digital technology as an effort to increase profits for the businesses they manage. This socialization program is designed to provide understanding and practical skills regarding digital marketing that can help MSMEs expand their markets, encourage innovation in marketing strategies. In addition, this program is expected to increase the competitiveness of village MSMEs and encourage the community's economy in a sustainable manner. The results of the community service activities from this socialization activity are that MSME actors gain increased knowledge and motivation for business actors in utilizing digital media for promotion. However, in this activity, there are obstacles encountered, namely in the process of mentoring MSMEs, it was found that some business actors experienced difficulty in understanding the material, especially related to the use of digital technology. One of the main factors influencing this is the age of the MSME actors. Older MSME actors tend to have limitations in keeping up with technological developments.
Co-Authors Amna, Eka Yunita Anidar Anidar, Anidar Ardianti, Zahra Azka Karimah, Naila Bakhita Fauzi, Hayya Fajar, Sukmawan Fajri, Fauzan Hasan, Denny Irmawati Herlina Dimiati, Herlina Indra Suyoto Kurniawan Mulya Safri, Mulya Nora Sovira, Nora Patimah, Titin Pradita Sari, Sindi Rahmatulloh, Fauzi Set Asmapane