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All Journal Jurnal Bioteknologi & Biosains Indonesia (JBBI) IIJSE Indonesian Journal of Jamu
Efendi, Julham
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology

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PROFIL HEMATOLOGI TIKUS (Rattus norvegicus) GALUR SPRAGUE-DAWLEY JANTAN UMUR 7 DAN 10 MINGGU Rosidah, Idah; Ningsih, Sri; Renggani, Tiya Novita; Efendi, Julham; Agustini, Kurnia
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 7 No. 1 (2020): June 2020
Publisher : Balai Bioteknologi, Badan Pengkajian dan Penerapan Teknologi (BPPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29122/jbbi.v7i1.3568

Abstract

Hematology Profile of Sprague-Dawley Male Rats (Rattus norvegicus) Aged 7 and 10 WeeksCurrently, the normal hematology profile has not been yet available for outbred rats in Indonesia. Most of the researchers use the data of hematology profile from references outside Indonesia in which the breeding environment is different. This study aimed to obtain a hematology profile of Sprague-Dawley male rats aged 7 and 10 weeks. The animals were obtained from the Laboratory of Animal Experiment, NADFC. Blood was drawn from the retro-orbital sinus and then analyzed to obtain the hematology profile including erythrocytes, hemoglobin, hematocrit, MCV, MCH, MCHC, leukocytes. Statistically significant differences for erythrocytes, hemoglobin, MCV, MCHC, thrombocyte, and leukocytes parameters were observed between rats aged 7 and 10 weeks. However, there were no statistically significant differences observed on MCH, thrombocyte, and body weight parameters. Data presented here would be useful as a reference for hematology research as well as in evaluating alterations in blood parameters.Keywords: erythrocyte, hematology, leukocyte, Sprague-Dawley, thrombocyteABSTRAKSaat ini belum banyak tersedia informasi profil hematologi untuk hewan coba tikus yang dikembangbiakkan di Indonesia. Kebanyakan peneliti menggunakan data profil hematologi dari referensi luar Indonesia. Penelitian ini bertujuan untuk mendapatkan data hematologi tikus jantan usia 7 dan 10 minggu.  Hewan coba yang digunakan adalah tikus jantan galur Sprague-Dawley yang diperoleh dari Laboratorium Hewan Percobaan-BPOM. Sebanyak 60 ekor tikus jantan yang terdiri dari 30 ekor usia 7 minggu dan 30 ekor usia 10 minggu diambil darahnya melalui sinus orbitalis. Selanjutnya, dianalisa jumlah sel eritrosit, hemoglobin, hematokrit, MCV, MCH, MCHC, leukosit. Hasil analisis statistik menunjukkan terdapat perbedaan signifikan antara tikus jantan usia 7 dan 10 minggu untuk parameter jumlah eritrosit, hemoglobin, hematokrit, MCV, MCHC dan leukosit. Tetapi tidak terdapat perbedaan signifikan untuk jumlah MCH, trombosit dan berat badan tikus. Data yang diperoleh dapat digunakan sebagai referensi penelitian yang berhubungan erat dengan profil hematologi dan penyakit kelainan darah lainnya.
Konsumsi Ekstrak Secang (Caesalpinia sappan L.) Terhadap Volume Urin Tikus Putih Jantan Galur Spraque Dawley Pertamawati, Pertamawati; Sriningsih, Sriningsih; Fahrudin, Fahri; Efendi, Julham
Jurnal Jamu Indonesia Vol. 2 No. 3 (2017): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v2i3.41

Abstract

Secara empiris secang (Caesalpinia sappan L.) dimanfaatkan sebagai bahan untuk mengatasi penyakit, namun bagaimana pengaruhnya terhadap pengeluaran urin belum diketahui. Penelitian ini bertujuan untuk mengetahui pengaruh konsumsi ekstrak secang terhadap pengeluaran urin. Percobaan dilakukan terhadap hewan coba tikus putih jantan galur Spraque dawley dengan sampel uji ekstrak etanol 96% kulit kayu secang. Hewan coba dibagi dalam 7 kelompok, masing-masing terdiri dari 6 ekor, yaitu kelompok normal, kelompok positif (Furosemide 10mg/200g BB), kelompok negatif (air 2ml/200g BB), kelompok sampel uji dosis I (62.5 mg/kg BB), dosis II (125mg/kg BB), dosis III (250mg/kg BB) dan dosis IV (500mg/kg BB), tigapuluh menit setelah pemberian sampel uji, hewan coba diberi air minum 4ml/200g BB dilakukan melalui sonde lambung, selanjutnya hewan coba dimasukkan ke dalam kandang metabolit selama 16 jam (overnight). Hewan coba dengan dosis II menghasilkan volume urin paling besar (8.00 mL) yaitu hampir dua kali lipat dibandingkan urin yang dihasilkan oleh kelompok normal (4.50 mL) Volume urin berkurang jika konsumsi ekstrak secang bertambah pada dosis III dan IV. Disimpulkan bahwa hewan coba yang diberi ekstrak kulit secang dengan dosis 125 mg/kg BB (dosis II) rata-rata mampu mengeluarkan urin lebih banyak daripada hewan coba dalam kelompok lainnya.
The Influence of Leadership Style, Work Environment, and Compensation on Teacher Performance Efendi, Julham; Nasution, Ade Parlaungan; Harahap, Aziddin
Indonesian Interdisciplinary Journal of Sharia Economics (IIJSE) Vol 6 No 2 (2023): Sharia Economics
Publisher : Sharia Economics Department Universitas KH. Abdul Chalim, Mojokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31538/iijse.v6i2.3410

Abstract

Teacher performance plays a very important role in the advancement of education in Indonesia, if the teacher’s performance is bad, then it will not lead to the best learning outcomes. All instructors must be able to complete their tasks quickly and accurately both in management and teaching. High-class sizes, a lack of student focus and dedication, and an abundance of extracurricular activities mean that teachers’ attention is not only divided but also thinly spread. While rare, teacher absences and free time during courses can hinder learning. In addition, the early departure of teachers is a very demoralizing event, and there are positive aspects such as the principal’s management style, unpleasant working atmosphere, and unclear salary. Teacher effectiveness plays an important role in supporting education in Indonesia. The program objectives will also not be achieved optimally if the teacher's performance is below standard. This study aims to analyze the influence of the principal’s leadership style, work environment, and compensation on teacher performance. The type of research used is quantitative research. The results of this study conclude that the principal’s leadership affects teacher performance, the work environment influences teacher performance, and compensation also affects teacher performance.
Co-Authors Ade Parlaungan Nasution, Ade Parlaungan Fahri Fahrudin, Fahri Harahap, Aziddin Idah Rosidah kurnia agustini Pertamawati Pertamawati Renggani, Tiya Novita Sri Ningsih Sriningsih Sriningsih, Sriningsih