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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Kesehatan Gigi JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Abdimas Madani dan Lestari (JAMALI)
Pertiwi, Deasy Vanda
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

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Kerinci Cinnamon Leaf (Cinnamomum burmanii) and Tangkit Pineapple Core (Ananas comosus) Extracts in Mouthwash Formulation: Potential for Preventing Dental Plaque Growth in Special Needs Childre Fitria, Karin Tika; Handayatun, Naning Nur; Baroroh, Faridah; Pertiwi, Deasy Vanda
Jurnal Kesehatan Gigi Vol 11, No 2 (2024): Desember 2024
Publisher : Jurusan Kesehatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v11i2.12021

Abstract

Dental plaque is a significant factor in developing oral diseases, particularly in children with special needs who may face challenges maintaining oral hygiene. This study explores the potential of a mouthwash formulation incorporating Kerinci cinnamon leaf (Cinnamomum burmanii) and Tangkit pineapple core (Ananas comosus) extracts in preventing dental plaque growth. Both extracts were chosen due to their known antibacterial properties and natural origin, making them suitable for children with sensitivities to synthetic chemicals. The formulation was tested in varying ratios to determine the most effective combination for inhibiting the growth of Streptococcus mutans, a primary bacterium responsible for dental plaque. The results indicated that a 50:50 ratio of cinnamon leaf and pineapple core extracts exhibited the highest antibacterial activity (p-value 0,034), outperforming other ratios such as 75:25 and 25:75. This suggests a synergistic interaction between the two extracts, enhancing their combined efficacy. Further research is recommended to optimize the formulation and evaluate its long-term effectiveness and safety in clinical settings
Penggunaan Herbal Balm Aromaterapi Essential Oil Bunga Lavender Sebagai Pencegahan Insomnia Usia Produktif di Universitas Aisyiyah Yogkakarta : Indonesia Faridah, Imaniar Noor; Pertiwi, Deasy Vanda; Hipmi, Ahmad Fahrian; Maulizah, Rizlah; Rahmawati, Sri
Jurnal Abdimas Madani dan Lestari (JAMALI) Volume 07, Issue 01, Maret 2025
Publisher : UII

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jamali.vol7.iss1.art10

Abstract

One of the basic human needs is sleep, every individual definitely needs enough sleep between 6-9 hours a day. The benefits you get from getting enough sleep include maintaining stamina and health. According to the World Health Organization (WHO), in Indonesia in 2020 around 10%, which means approximately 28 million of the totals 238 million Indonesian population suffer from insomnia. Insomnia is a symptom of difficulty sleeping which is usually caused by bad behavior or habits before bed. In general, teenagers often experience insomnia due to consuming too much caffeine (coffee). The aim of this empowerment program activity is to provide more knowledge regarding insomnia and making lavender essential oil aromatherapy balm to help reduce insomnia that occurs among students, especially at Aisyiyah University, Yogyakarta, as well as increasing student creativity. in entrepreneurship. The implementation method was carried out by counseling about insomnia and the practice of making aromatherapy balm as an alternative treatment for insomnia at Aisyiyah University, Yogyakarta. Making aromatherapy balm preparations using an inhalation mechanism is very effective and easy to apply while traveling. The results of data analysis from giving questionnaires to students regarding insomnia knowledge showed that the score at the pretest was 50% (poor category), and the posttest had a score of 76.8% (good category). The results of this analysis showed that there was a significant difference in scores before and after giving the counseling. insomnia in productive age at Aisyiyah University Yogyakarta. Aromatherapy balm therapy as an alternative to reduce insomnia. Lavender aroma therapy contains linalool acetate which is able to relax and relax the nervous system and tense muscles by increasing the frequency of alpha waves and this condition is associated with treating insomnia.
FORMULASI DAN KARAKTERISASI SEDIAAN HIDROGEL MINYAK CENGKEH (Syzygium aromaticum) BERBASIS KITOSAN Pertiwi, Deasy Vanda; Ikhsanudin, Azis; Sugihartini, Nining
Media Farmasi: Jurnal Ilmu Farmasi Vol. 14 No. 1: Maret 2017
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v14i1.9831

Abstract

Eugenol merupakan kandungan utama minyak cengkeh yang memiliki potensi sebagai anti inflamasi. Bentuk sediaan yang berupa cairan berminyak menimbulkan ketidaknyamanan dan tidak bertahan lama untuk kontak dengan kulit sehingga efikasi yang diharapkan tidak tercapai jika digunakan langsung pada permukaan kulit. Oleh karena itu, dibutuhkan sistem sediaan yang dapat menghantarkan obat menembus kulit dengan lebih baik. Hidrogel adalah sediaan semipadat yang diharapkan dapat  diaplikasikan sebagai pembawa minyak cengkeh, sehingga akan meningkatkan kenyamanan dan efikasinya. Pembuatan hidrogel minyak cengkeh dilakukan dengan memformulasikan minyak cengkeh, surfaktan tween 80 dan propilen glikol (PG) menjadi emulsi. Desain formula dibuat menggunakan Design Expert 10 trial. Formula emulsi yang optimum selanjutnya diformulasikan dengan basis gel kitosan konsentrasi 4% dan 5%. Hidrogel minyak cengkeh diformulasikan menjadi emulsi yang selanjutnya ditambahkan ke dalam basis gel berupa kitosan. Dari hasil uji karakterisasi gel diperoleh bentuk emulgel berwarna putih kekuningan dengan pH 6. Uji daya sebar menunjukkan formula 1 dengan basis kitosan 5% memiliki daya sebar yang paling baik, yaitu 5,1 cm. Hasil uji daya lekat menunjukkan bahwa keempat formula memenuhi syarat uji daya lekat, yaitu tidak kurang dari 4 detik. Dari uji karakteristik, formula F1 5% merupakan formula yang optimal karena memenuhi semua persyaratan sifat fisik. Hal tersebut menunjukkan bahwa minyak cengkeh dapat menghasilkan sediaan gel yang baik dengan basis kitosan.
Investigating the Impact of Surfactant and Cosolvent on the Polyphenolic Content in Arumanis Mango Leaf Extract (Mangifera indica L.) Fatimah, Siti Fatmawati; Farida, Verda; Nuari, Yudha Rizky; Viviandhari, Daniek; Pertiwi, Deasy Vanda
JSFK (Jurnal Sains Farmasi & Klinis) Vol 11 No 1 (2024): J Sains Farm Klin 11(1), April 2024
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.11.1.39-47.2024

Abstract

The leaf of Mangifera indica L. contains flavonoids and mangiferin which showed positive effects on wound healing of diabetic ulcer. The used of suitable surfactant and co-solvent is required to ensure the high solubility of the active pharmaceutical ingredient (API), thereby optimizing the efficacy. This study aims to determine the ideal surfactant and cosolvent for a thermosensitive hydrogel formula of Mangifera indica leaf ethanol extract. The leaf was fextracted by maceration using 70% ethanol then determined for moisture content.  The extract was prepared for solubility tests of flavonoid and mangiferin on surfactants (Kolliphor® EL, Tween® 20, Tween® 80, Miranol® C2M) and co-solvents (Glycerin, PEG 400, and transcutol). Methods for total flavonoids content were Spectrophotometry UV-Vis and mangiferin with RP-HPLC method. The moisture content in the extract is 8.590 ± 0.754%. The surfactant demonstrating the highest capability in flavonoid dissolution is Tween 20 (1863.750 ± 0.838 µgQE/g extract), followed by Tween 80, Kolliphor EL, and Miranol C2M. In the context of co-solvents, PEG 400 (1309.583 ± 0.292 µgQE/g extract) show superior flavonoid dissolution capability, with glycerin and Transcutol following in descending order. Tween 20 and Tween 80 exhibite comparable efficacy in mangiferin dissolution, followed by Miranol C2M and Kolliphor EL. Among co-solvents, Transcutol demonstrate the highest aptitude for mangiferin dissolution, succeeded by PEG 400 and glycerin. This study indicates Tween 20 is a preferable surfactant and PEG 400 was considered as co-solvent to be further used in a thermosensitive gel formula for diabetic ulcer. 
Kerinci Cinnamon Leaf (Cinnamomum burmanii) and Tangkit Pineapple Core (Ananas comosus) Extracts in Mouthwash Formulation: Potential for Preventing Dental Plaque Growth in Special Needs Childre Fitria, Karin Tika; Handayatun, Naning Nur; Baroroh, Faridah; Pertiwi, Deasy Vanda
Jurnal Kesehatan Gigi Vol. 11 No. 2 (2024): Desember 2024
Publisher : Jurusan Kesehatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v11i2.12021

Abstract

Dental plaque is a significant factor in developing oral diseases, particularly in children with special needs who may face challenges maintaining oral hygiene. This study explores the potential of a mouthwash formulation incorporating Kerinci cinnamon leaf (Cinnamomum burmanii) and Tangkit pineapple core (Ananas comosus) extracts in preventing dental plaque growth. Both extracts were chosen due to their known antibacterial properties and natural origin, making them suitable for children with sensitivities to synthetic chemicals. The formulation was tested in varying ratios to determine the most effective combination for inhibiting the growth of Streptococcus mutans, a primary bacterium responsible for dental plaque. The results indicated that a 50:50 ratio of cinnamon leaf and pineapple core extracts exhibited the highest antibacterial activity (p-value 0,034), outperforming other ratios such as 75:25 and 25:75. This suggests a synergistic interaction between the two extracts, enhancing their combined efficacy. Further research is recommended to optimize the formulation and evaluate its long-term effectiveness and safety in clinical settings
Co-Authors Azis Ikhsanudin Faridah Baroroh Fitria, Karin Tika Handayatun, Naning Nur Hipmi, Ahmad Fahrian Imaniar Noor Faridah Maulizah, Rizlah Nining Sugihartini Nuari, Yudha Rizky Raden Mohamad Herdian Bhakti Siti Fatmawati Fatimah, Siti Fatmawati Verda Farida Viviandhari, Daniek