Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Journal Of Vocational Health Studies Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Sugihartina, Ganthina
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
ELEVATED BLOOD LEAD LEVELS IN WOMEN OF REPRODUCTIVE AGE DUE TO LEADS EXPOSURE FROM CONTAMINATED WATER Nursidika, Perdina; Kurnia, Dedeh; Sugihartina, Ganthina
Journal of Vocational Health Studies Vol. 7 No. 3 (2024): March 2024 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V7.I3.2024.175-180

Abstract

Background: Water quality can decrease due to population growth, domestic waste handling, climate, and human activities. Most of the people in Cimahi use well water for drinking and eating. However, using well water with high lead levels for consumption can adversely affect on the lead levels in the women's blood of childbearing age. Purpose: This study investigates the relationship between lead levels in well water and the corresponding levels found in women's blood in the Leuwigajah area of Cimahi. Method: Research samples were collected from both well water and the women's blood of childbearing age (15 - 49 years) who consume well water for drinking and cooking. Subsequently, sample preparation was conducted, and the samples were analyzed using an atomic absorption spectrophotometer. The Spearman correlation test was employed to analyze the data and establish any potential correlations. Result: The lead content in water ranged from 0.055 ppm to 0.089 ppm, exceeding the requirements for lead in clean water. Meanwhile, lead levels in the blood ranged from 1.5 ug/dL to 78.2 ug/dL, with 6.7% falling within the normal category, 40% in the tolerable category, 30% in the excess category, and 23.3% in the high category. The statistical results show a significant relationship between lead levels in well water and the blood, with a correlation value of 37.9%. The correlation value indicates a weak positive relationship. Conclusion: There is a relationship between lead levels in well water and women's blood.
DIFFERENCES IN THE STABILITY OF CHOLINESTERASE ENZYME ACTIVITY OF SERUM AND HEPARIN PLASMA SAMPLES USING PHOTOMETRIC KINETIC METHOD Rohayati, Rohayati; Budiana, Lufthy Leidi; Indra, Asep Iin Nur; Sugihartina, Ganthina
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 16 No 2 (2024): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v16i2.2777

Abstract

Kesalahan dalam pemeriksaan laboratorium dapat terjadi pada setiap fase proses pengujian, tetapi sebagian besar kesalahan terjadi pada fase pra analitik dengan kontribusi sebesar 70%. Pemeriksaan kolinesterase merupakan pemeriksaan pada keracunan pestisida untuk mendeteksi adanya gangguan kesehatan yang kronis bahkan mematikan. Penelitian ini bertujuan untuk mengetahui stabilitas aktivitas enzim kolinesterase pada sampel serum dan plasma heparin pada suhu ruang. Penelitian ini dilakukan di Laboratorium Kimia Klinik Teknologi Laboratorium Medis Poltekkes Bandung pada bulan Mei 2024. Penelitian ini bersifat quasy experimental dengan memberi perlakuan berupa penyimpanan terhadap sampel serum dan plasma heparin selama 6 dan 24 jam pada suhu ruang yang kemudian aktivitas enzim kolinesterase dibandingkan dengan aktivitas enzim kolinesterase pada serum dan plasma heparin yang segera diperiksa. Pemeriksaan dilakukan dengan metode kinetik fotometrik menggunakan alat fotometer dengan panjang gelombang 405 nm dan dilakukan replikasi sebanyak 3 kali, sehingga didapatkan 90 data yang kemudian diolah menggunakan SPSS dengan uji general linear model (GLM). Secara statistik pada hasil uji GLM pada sampel serum dan plasma heparin menunjukkan nilai p < 0.05 yang berarti terdapat perbedaan stabilitas antara serum dan plasma heparin. Namun, berdasarkan hasil analisa secara klinis nilai Total Error (TE%) dengan penundaan selama 6 jam dan 24 jam terhadap pemeriksaan segera pada sampel serum secara berturut-turut sebesar 1,68% dan 6,44%, sedangkan pada sampel plasma heparin sebesar 3,66% dan 6,95%. Pemeriksaan kolinesterase memiliki nilai TEa% sebesar 8,9%, sehingga baik sampel serum maupun plasma heparin memiliki nilai TE% < TEa%. Berdasarkan hasil tersebut tidak terdapat perbedaan secara klinis.
Co-Authors Budiana, Lufthy Leidi Indra, Asep Iin Nur KURNIA, DEDEH Perdina Nursidika rohayati rohayati