Claim Missing Document
Check
Articles

Found 10 Documents
Search

AKTIVITAS ANTIMIKROB FRAKSI EKSTRAK ETANOL BUAH PINANG (ARECA CATECHU L) PADA BAKTERI METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS Nursidika, Perdina; Saptarini, Opstaria; Rafiqua, Nurul
Majalah Kedokteran Bandung Vol 46, No 2 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1639.673 KB)

Abstract

Infeksi merupakan penyakit penyebab kematian di Indonesia. Salah satu penyebab perkembangan penyakit infeksi di Indonesia adalah resistensi bakteri terhadap antibiotik standar. Methicillin resistant Staphylococcus aureus (MRSA) merupakan penyebab utama infeksi nosokomial dan komunitas.Telah dilakukan uji aktivitas antimikrob fraksi dari ekstrak etanol buah pinang (Areca catechu L) pada bakteri MRSA. Penelitian dilaksanakan di Laboratorium Mikrobiologi Stikes Jenderal Achmad Yani Cimahi, Laboratorium Farmakologi Institut Teknologi Bandung, dan Laboratorium Pusat Penelitian dan Pengembangan Geologi Kelautan Bandung pada Mei?Juni 2011. Aktivitas antimikrobekstrak dan fraksi diuji menggunakan metode broth microdilution, bioautografi, dan scanning electron microscope (SEM). Hasil pengujian menunjukkan bahwa fraksi yang paling efektif ialah fraksi air dengan minimum inhibitory concentration (MIC) 256 µg/mL. Hasil bioautografi menunjukkan bercak kromatogram kromatografi lapis tipis (KLT) yang memberikan hambatan terhadap bakteri uji adalah bercak dengan Rf 0,6. Bercak ini diduga merupakan senyawa fenolat karena memberikan hasil positif dengan penyemprotan FeCl3. Hasil SEM menunjukkan bakteri uji yang telah dipapar dengan tanaman uji diduga mengalami kerusakan pada membran atau bagian yang lebih dalam, sehingga sel bakteri menciut dan bergelembung hingga rusak.Simpulan, ekstrak etanol buah pinang dapat menghambat pertumbuhan bakteri MRSA. [MKB. 2014;46(2):94?9]Kata kunci: Aktivitas antimikrob, Areca catechu, microdilution, MRSA, SEM Antimicrobial Activity of Betel Nut Ethanolic Extract Fractions in Methicillin Resistant Staphylococcus aureusInfection is the major cause of death in Indonesia. Antibiotic resistant is responsible for this progression. Methicillin resistant Staphylococcus aureus (MRSA) is known as the main cause of nosocomial and community infections.The antimicrobial activity of ethanolic extract fractions of betel nut (Areca catechu L) was studied on MRSA. The research was performed at the Microbiology Laboratory, School of Health Sciences, Jenderal Achmad Yani University, Cimahi, the Pharmacology Laboratory of Bandung Institute of Technology, and Research and Development of Ocean Geology Laboratory in May?June 2011.The antimicrobial activities of the extract and fraction were tested by microdilution broth method, bioautography and scanning electron microscope (SEM). The most effective result showed by water fraction with minimum inhibitory concentration (MIC) was 256 µg/mL. Bioautography result showed a spot on thin layer chromatography (TLC) chromatogramof water fraction which inhibited the bacterial growth, which was the spot with Rf 0.6. The spot was suggested as a phenolic substance due to positive result to FeCl3. The electron microscope image showed the breakdown of membrane cell/inner site of bacteria which was exposed by betel nut extract and fractions in which the bacteria was shrinked, bubbled and broken.In conclusion, betel nut ethanolic extract has the ability to inhibit MRSA. [MKB. 2014;46(2):94?9]Key words: Antimicrobial activity, Areca catechu, microdillution, MRSA,SEM DOI: 10.15395/mkb.v46n2.280
Potensi Asam Lemak Pada Minyak Kelapa Murni Dalam Menghambat Candida Albicans Secara In Vitro Novilla, Arina; Nursidika, Perdina; Resmelia, Meyli
Majalah Kedokteran Bandung Vol 48, No 4 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (253.101 KB) | DOI: 10.15395/mkb.v48n4.910

Abstract

Kandidiasis merupakan penyakit infeksi Candida baik primer maupun sekunder. Penyebab utama kandidiasis adalah Candida albicans (C. albicans). Pengobatan kandidiasis dilakukan dengan pemberian obat anti jamur, terutama nistatin, amfoterisin-B dan azole, tetapi toksisitas dan resistensi obat ini menjadi masalah potensial. Diperlukan pemakaian obat lain yang lebih aman. Salah satunya adalah pemanfaatan bahan alami yaitu minyak kelapa murni. Tujuan penelitian ini adalah untuk mengetahui potensi asam lemak minyak kelapa murni dalam menghambat pertumbuhan C. albicans. Desain penelitian eksperimental. Penelitian menggunakan difusi Kirby Bauer untuk mendapatkan konsentrasi hambat minimum minyak kelapa murni dalam menghambat C. albicans. Penelitian dilakukan pada bulan September–Oktober 2010 di Laboratorium Kimia dan Mikrobiologi Sekolah Tinggi Ilmu Kesehatan Jenderal Achmad Yani Cimahi. Hasil menunjukkan asam lemak dalam fraksi n-heksan dan metanol hasil hidrolisis berpotensi dalam menghambat pertumbuhan C. albicans. Fraksi n-heksan konsentrasi minimal yang memberikan hambatan yaitu 75% dengan diameter hambatan rata-rata sebesar 3,3 mm, sebanding dengan antibiotik nistatin 195 unit. Fraksi metanol memberikan hambatan dimulai pada konsentrasi 75% dengan diameter hambatan rata-rata sebesar 4 mm, sebanding dengan antibiotik nistatin 195 unit. Hasil konsentrasi hambat minimum masing-masing asam lemak untuk fraksi metanol konsentrasi 25% dan fraksi n-heksan 100%. Simpulan, asam lemak pada minyak kelapa murni dapat menghambat C. albicans. [MKB. 2016;48(4):200–4]Kata kunci: asam lemak, Candida albicans, in vitro, minyak kelapa murniPotential Of Virgin Coconut Oil Fatty Acid to Inhibit the Growth of Candida Albicans In VitroAbstractCandidiasis is Candida infection both primary or secondary diseases. The main cause of candidiasis is Candida albicans (C. albicans). Candidiasis is treated by antifungal drug treatment, especially nistatin, amphotericin-B, and azole, but toxicity and drug resistance become potential problems. Therefore, other method is needed as safer treatment. One of natural resources which has antifungal is virgin coconut oil. Research design was experimental. The objective of study was determine the potential of fatty acid in virgin coconut oil to inhibit C. albicans. This study used Kirby Bauer Method to determine minimum inhibition concentration. The study was performed in September-October 2010 at Chemistry and Microbiology Laboratory School of Health Sciences Jenderal Achmad Yani Cimahi. The result showed the fatty acid of n-hexane and methanol fractions after hydrolysed were potential to inhibit the growth of C. albicans. Minimum inhibitory concentration against C. albicans was 75% with average diameter of inhibiting zone 3.3 mm was equal to nistatin 195 units. The methanol fraction inhibited C. albicans start from 75% with average diameter 4 mm or equal to nistatin 195 units. Minimum fungicidal concentration showed C. albicans inhibited by methanol fraction 25% and n-hexane fraction with concentration 100%. In conclusion, fatty acid of virgin coconut oil was able to inhibit C. albicans. [MKB. 2016;48(4):200–4]Key words: Candida albicans, fatty acids, in vitro, virgin coconut oil
ELEVATED BLOOD LEAD LEVELS IN WOMEN OF REPRODUCTIVE AGE DUE TO LEADS EXPOSURE FROM CONTAMINATED WATER Nursidika, Perdina; Kurnia, Dedeh; Sugihartina, Ganthina
Journal of Vocational Health Studies Vol. 7 No. 3 (2024): March 2024 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V7.I3.2024.175-180

Abstract

Background: Water quality can decrease due to population growth, domestic waste handling, climate, and human activities. Most of the people in Cimahi use well water for drinking and eating. However, using well water with high lead levels for consumption can adversely affect on the lead levels in the women's blood of childbearing age. Purpose: This study investigates the relationship between lead levels in well water and the corresponding levels found in women's blood in the Leuwigajah area of Cimahi. Method: Research samples were collected from both well water and the women's blood of childbearing age (15 - 49 years) who consume well water for drinking and cooking. Subsequently, sample preparation was conducted, and the samples were analyzed using an atomic absorption spectrophotometer. The Spearman correlation test was employed to analyze the data and establish any potential correlations. Result: The lead content in water ranged from 0.055 ppm to 0.089 ppm, exceeding the requirements for lead in clean water. Meanwhile, lead levels in the blood ranged from 1.5 ug/dL to 78.2 ug/dL, with 6.7% falling within the normal category, 40% in the tolerable category, 30% in the excess category, and 23.3% in the high category. The statistical results show a significant relationship between lead levels in well water and the blood, with a correlation value of 37.9%. The correlation value indicates a weak positive relationship. Conclusion: There is a relationship between lead levels in well water and women's blood.
The Effect of Stress Levels on Blood Glucose Levels in Medical Laboratory Technology Final-Year Students Nursidika, Perdina; Astari, Risti Maulani; Furqon, Ayi
Mukhtabar Journal of Medical Laboratory Technology Vol 2 No 2 (2024): Mukhtabar: Journal of Medical Laboratory Technology (October 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/mjmlt.v2i2.684

Abstract

Background & Objective: Final-year students are a group that experiences stress due to academic life, responsibilities, and demands from the academic world, such as completing theses, fieldwork, and other academic burden. In addition, the current pandemic may cause stress related to communication and daily life changes. Stress increases the release of epinephrine, catecholamine, glucagon, glucocorticoids, beta-endorphin, and growth hormone, which causes excessive cortisol production, increasing blood sugar levels. This study aimed to determine the relationship between stress levels and blood sugar levels in undergraduate students in medical laboratory technology. Method: This research method used a cross-sectional approach, with 35 samples that fit the inclusion criteria. The stress measuring tool used was the Depression Anxiety Stress Scale (DASS) questionnaire. Blood glucose examination using the Glucose Oxidase Peroxidase Aminoantypirin method. The analysis used in this study is the correlation test using the Chi-square test Result: Stress levels in students show normal stress at as much as 11% mild stress at 26% moderate stress at 46%, and severe stress at as much as 17%. The results of bivariate analysis between stress levels and blood glucose levels were p=0.012 (p<0.05). Conclusion: there is a significant relationship between stress levels and blood glucose levels in final-year students of D4 Medical Laboratory Technology at Jenderal Achmad Yani University, Cimahi. The results of this study became one of the prediabetes screening data. The need for stress management in students can be one of the factors to avoid the risk of diabetes.
Fungistatic activity and mechanism of Caulerpa racemosa, Caulerpa lentillifera fractions and caulerpin metabolite against pathogenic fungi Nursidika, Perdina; Julianti, Elin; Kurniati, Neng F.
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1714

Abstract

The increasing prevalence of azole resistance in various fungal species presents a significant concern, highlighting the urgent need for new antifungal agents. The aim of this study was to investigate the antifungal activity of fractions from Caulerpa racemosa, C. lentillifera, and caulerpin against three species: Aspergillus flavus, A. niger, and Candida albicans. The Caulerpa extracts were obtained through maceration with 96% ethanol, followed by fractionation using vacuum liquid chromatography. Antifungal activity was assessed using the broth microdilution method, while fungal growth kinetics were evaluated through time-kill curves. Bioautography was employed to identify inhibitory compounds, while liquid chromatography high-resolution mass spectrometry (LC-HRMS) was utilized to detect the contents of the extracts and fractions. Scanning electron microscopy (SEM) was used to observe the fungal structure, and the absorbance at 260/280 nm was measured to evaluate the cell leakage. LC-HRMS identified numerous compounds in C. racemosa and C. lentillifera with antifungal activities, including fatty acids, terpenes, alkaloids, flavonoids, and coumarins. The results indicate that the fractions of both Caulerpa did not inhibit the growth of A. flavus and A. niger, but effectively inhibited C. albicans. Among the fractions, F3CR and F4CL exhibited the highest antifungal efficacy against C. albicans, with minimum inhibitory concentrations (MICs) ranging from 64 to 128 µg/mL. Caulerpin, the primary metabolite of Caulerpa, also demonstrated significant inhibition, with an MIC of 256 µg/mL. The findings suggested that F3CR, F4CL, and caulerpin possessed fungistatic properties. Bioautography results revealed clear zones in the colonies, indicating inhibited fungal growth. The SEM observations showed that fungal cells became rough, perforated, and damaged, which was confirmed by the increase in absorbance at 260/280 nm, suggesting the release of cellular components such as nucleotides and proteins. In conclusion, both Caulerpa species and caulerpin are promising candidates for developing new antifungal agents against C. albicans.
Manipedicare Upaya Pencegahan Cacingan dan Peningkatan Kesadaran Kebersihan pada Anak SD di Cimahi Berutu, Astri Lafenia; Febrianti, Vina; Khairunissa, Tasya Salsabilla; Hasna, Natasya Aliatul; Nurkurnia, Isyfi; Nursidika, Perdina
Jurnal Abdimas Kartika Wijayakusuma Vol 5 No 3 (2024): Jurnal Abdimas Kartika Wijaya Kusuma
Publisher : LPPM Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jakw.v5i3.504

Abstract

Manipedicare adalah program perawatan kuku dengan tujuan mencegah cacingan dan meningkatkan kesadaran untuk anak-anak sekolah dasar (SD) di Cimahi. Jumlah penderita cacingan di Indonesia masih cukup tinggi, dan cacingan termasuk dalam Penyakit Tropis Terabaikan (Neglected Tropical Diseases/NTDs) yang masih menjadi prioritas penanganan di Indonesia. Pengabdian masyarakat ini bertujuan untuk merawat dan memeriksa kuku tangan serta memberikan edukasi untuk mengenalkan dan menanamkan kesadaran tentang kebersihan pribadi pada siswa SD L sehari-hari. Metode pengabdian masyarakat ini meliputi berbagai tahap, yaitu survei lokasi, edukasi melalui penyuluhan, pemeriksaan kebersihan kuku, tes laboratorium untuk memeriksa telur cacing dengan metode NaCl, dan evaluasi kegiatan. Hasil dari kegiatan program Manipedicare menemukan bahwa masih ada tiga siswa yang positif terdapat telur cacing Ascaris lumbricoides dan Ancylostoma duodenale di kuku mereka, namun hal ini telah ditindaklanjuti dengan pemeriksaan feses dan pemberian obat cacing. Hasil dari program ini juga menunjukkan peningkatan kebiasaan siswa SD L dalam membersihkan tangan dan kuku mereka, yang terlihat dari peningkatan jumlah siswa yang mengubah kebiasaan dari 234 siswa sebelum edukasi menjadi 340 siswa. Program Manipedicare ini dapat dinyatakan berhasil. Hasil menunjukkan masih ditemukan siswa yang menderita cacingan, sehingga perlu dilakukan tindak lanjut berupa perbaikan status gizi atau pemeriksaan laboratorium yang lebih komprehensif.
Manicare Upaya Pencegahan Cacingan dan Peningkatan Kesadaran Kebersihan Pada Anak Sekolah Dasar di Cimahi Febrianti, Vina; Berutu, Astri Lafenia; Khairunissa, Tasya Salsabilla; Hasna, Natasya Aliatul; Nurkurnia, Isyfi; Naully, Patricia Gita; Nursidika, Perdina
JURNAL KESEHATAN KARTIKA Vol. 20 No. 1 (2025): Jurnal Kesehatan Kartika
Publisher : Faculty of Health Science and Technology, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkkes.v20i1.435

Abstract

Background: Helminth infections are common among elementary school children in areas with poor sanitation, often resulting in anemia, growth disorders, and weakened immunity. A lack of awareness about personal hygiene, particularly nail cleanliness, contributes significantly to this problem. Objective: This study aimed to evaluate the effectiveness of the Manicare program, an educational intervention designed to improve students’ awareness and practices regarding nail hygiene. Methods: . A quantitative experimental design was used, involving 76 students from SD Negeri Linggabudi, Cimahi, selected through purposive sampling based on the presence of long and dirty nails. Nail samples were examined in the laboratory before and after the Manicare intervention, and students’ awareness of nail hygiene was assessed through direct observation. Data were analyzed using the Chi-Square test Results: The results of the study of 309 students showed that before the intervention, 76 students (24.6%) had long and dirty nails, while 233 students (75.4%) had short and clean nails. After the four-week intervention, all students had short and clean nails (100%). Laboratory examinations revealed that 1 student (1.3%) tested positive for helminth eggs before the intervention, whereas post-intervention results showed no helminth eggs in the examined samples. Conclusion: the Manicare program effectively improved students’ nail hygiene and may reduce the risk of helminth infections. Regular implementation of this program could serve as an effective preventive measure among elementary school children.
Edukasi Kesehatan sebagai Upaya Preventif Penyakit Hepatitis B dan C pada Warga Binaan Pemasyarakatan Naully, Patricia Gita; Nursidika, Perdina
Aksiologiya: Jurnal Pengabdian Kepada Masyarakat Vol 4 No 1 (2020): Februari
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/aks.v4i1.2164

Abstract

ABSTRAK Hepatitis B dan C dianggap paling berbahaya diantara jenis hepatitis yang lain karena keduanya dapat berkembang menjadi penyakit kronik, sering tanpa gejala, dan menyebabkan kematian. Salah satu upaya yang disarankan oleh WHO untuk mencegah peningkatan angka Hepatitis B dan C adalah melakukan kegiatan edukasi kesehatan bagi masyarakat, khususnya kelompok beresiko tinggi seperi Warga Binaan Pemasyarakatan (WBP). Oleh sebab itu, kegiatan penyuluhan ini bertujuan untuk meningkatkan pengetahuan WBP terkait penyebab, gejala, cara penularan, pencegahan, dan layanan kesehatan yang disediakan oleh pemerintah. Kegiatan ini dilakukan di Lembaga Pemasyarakatan (Lapas) Narkotika Kelas IIA Bandung dengan jumlah peserta sebanyak 30 orang WBP. Penyuluhan dilaksanakan dengan metode ceramah. Evaluasi kegiatan dilakukan dengan cara menganalisis hasil kuesioner dan nilai tes para peserta. Teknik analisis yang digunakan adalah analisis deskriptif. Hasil evaluasi membuktikan bahwa mayoritas WBP melakukan tindakan beresiko tinggi karena keterbatasan pengetahuan dan informasi, namun setelah mendapatkan materi penyuluhan terlihat adanya peningkatan nilai tes pada seluruh peserta. Kegiatan ini berhasil meningkatkan pengetahuan WBP di Lapas Narkotika Kelas IIA Bandung terkait penyebab, gejala klinis, cara penularan, pencegahan, serta beberapa layanan kesehatan pemerintah untuk mencegah, mendiagnosa, serta mengobati penyakit Hepatitis B dan C.Kata Kunci: hepatitis B; hepatitis C; penyuluhan; lembaga pemasyarakatanABSTRACTHepatitis B and C are considered as the most dangerous hepatitis types compared to the other, because both can develop into chronic diseases, asymptomatic, and cause death. One of the methods suggested by WHO to prevent an increase of Hepatitis B and C numbers is to conduct health education activities for the community, especially for the high-risk groups such as prisoners (WBP). Therefore, the aim of this extension activity was to upgrade the WBP's knowledge regarding the disease causes, symptoms, transmission methods, prevention, and health services provided by the government. This activity was conducted in Bandung Narcotics Penitentiary class IIA, with 30 WBP participants. The extention was done by the lecture method. Then, the activity evaluation was done by analyzing of questionnaire results and participants' test-scores. Besides, the analysis technique used was descriptive analysis. The evaluation result proved that the majority of WBP taking the high-risk action due to the limited of knowledge and information, but there was a test-score increase for all participants after obtaining counseling materials. This activity was successful to improve the WBP's knowledge in Bandung Narcotics Penitentiary class IIA related to the causes, clinical symptoms, modes of transmission, prevention, and also some government health services to prevent, diagnose, and treat the Hepatitis B and C.Keywords : extension; hepatitis B; hepatitis C; prison.
Upaya Pencegahan Penyebaran Covid-19 di Lingkungan Stikes Jenderal Achmad Yani Cimahi dengan Pemeriksaan Antibodi SARS-COV-2 Naully, Patricia Gita; Nursidika, Perdina; Kania, Prina Puspa; Rachmawati, Firdha
Aksiologiya: Jurnal Pengabdian Kepada Masyarakat Vol 6 No 3 (2022): Agustus
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/aks.v6i3.6781

Abstract

Peningkatan angka kejadian Covid-19 terjadi disebabkan akibat beban populasi yang cukup tinggi di wilayah Jawa Barat. Cluster-cluster baru terdiri dari kasus di pemukiman penduduk, di mana rata-rata saat dilakukan penelusuran bisa menginfeksi anggota keluarga lainnya. Peningkatan cluster di pemukiman penduduk cukup dikhawatirkan karena beberapa penduduk sudah kurang menerapkan protokol kesehatan untuk Covid-19. Penduduk di daerah lingkungan Stikes Jenderal Achmad Yani pun termasuk kurang menerapkan protokol kesehatan, seperti sering terlihat kerumuman warga dan lalai menggunakan masker, sehingga dikhawatirkan menjadi pembawa penyakit untuk keluarga dan menimbulkan cluster baru. Lingkungan Stikes Jenderal Achmad Yani dekat dengan Rumah Sakit Pusat Rujukan Covid-19 di Jawa Barat. Program Studi Teknologi Laboratorium Medis (TLM) D-4 sebagai salah satu program studi yang terlibat dalam diagnosis penyakit, berinisiatif untuk melakukan pemeriksaan skrining Covid-19. Kegiatan ini dilakukan dengan memeriksa antibodi SARS-COV-2 dengan metode imunokromatografi terhadap 50 warga di sekitar kampus. Semua kegiatan pemeriksaan dilakukan sesuai dengan protokol yang diberlakukan oleh Kementrian Kesehatan Republik Indonesia dan World Health Organization. Hasil pemeriksaan menunjukkan 98% sampel non reaktif dan 2% reaktif. Sampel dengan hasil reaktif ditindaklanjuti dengan pemeriksaan lanjut menggunakan teknik Polymerase Chain Reaction. Selain pemeriksaan, sampel diberikan edukasi untuk tetap mengikuti protokol kesehatan dan menjaga lingkungan dari penularan Covid-19.
Pencegahan HIV/AIDS serta Penyakit Degeneratif melalui Edukasi dan Pemeriksaan Laboratorium pada Remaja di MAN 1 Cimahi Kania, Prina Puspa; Furqon, Ayi; Gunawan, Taufik; Khairinisa, Gina; Nursidika, Perdina; Naully, Patricia Gita; Friliansari, Lilis Puspa; Ningrum, Nining Ratna; Rachmawati, Firdha
Jurnal Abdimas Kartika Wijayakusuma Vol 6 No 3 (2025): Jurnal Abdimas Kartika Wijayakusuma
Publisher : LPPM Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jakw.v6i3.726

Abstract

Remaja merupakan kelompok individu yang sedang mengalami berbagai perubahan penting, baik secara fisik maupun psikologis. Perubahan psikologis seringkali menimbulkan rasa ingin tahu yang tinggi, termasuk terhadap perilaku seks bebas yang berpotensi meningkatkan risiko penularan HIV/AIDS. Selain itu, pola makan yang kurang sehat akibat kebiasaan mengonsumsi makanan siap saji juga berdampak pada meningkatnya risiko penyakit degeneratif di kalangan remaja. Berdasarkan permasalahan tersebut, dilaksanakan kegiatan Pengabdian kepada Masyarakat (PKM) bertajuk “Pencegahan HIV/AIDS serta Penyakit Degeneratif melalui Edukasi dan Pemeriksaan Laboratorium pada Remaja di MAN 1 Cimahi.” Kegiatan ini melibatkan siswa-siswi MAN 1 Cimahi dan dilaksanakan melalui tahapan sosialisasi, pelaksanaan, serta evaluasi. Evaluasi dilakukan dengan memberikan pretest dan post-test untuk menilai peningkatan pengetahuan peserta terkait materi edukasi, serta pemeriksaan kesehatan melalui uji laboratorium. Hasil kegiatan menunjukkan adanya peningkatan signifikan pada tingkat pengetahuan remaja setelah diberikan edukasi. Berdasarkan hasil pemeriksaan terhadap 50 siswa-siswi, seluruh peserta dinyatakan bebas HIV/AIDS dengan rata-rata kadar glukosa darah sewaktu sebesar 110,2 mg/dL. Dengan demikian, hasil skrining menunjukkan bahwa kondisi kesehatan siswa-siswi MAN 1 Cimahi berada dalam kategori normal.