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All Journal Jurnal Farmasi Jurnal Farmasi dan Sains Indonesia (JFSI) Science and Community Pharmacy Journal
Puruhita, Ranatri
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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BROCCOLI (Brassica oleracea L) ETHANOL EXTRACT: A MOISTURIZER AND ITS EVALUATION IN ASPECTS OF PHYSICAL CHARACTERISTICS Aldila, Silvy; Puruhita, Ranatri; Uliana, Syahkhirotul Exma; Sa’adah, Anifatus; Gloria, Fransisca
Science and Community Pharmacy Journal Vol. 3 No. 1 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i1.545

Abstract

Skin disorders that are dry, dull, scaly, and not fresh affect everyone. Moisturizing cream is a cosmetic product that effectively hydrates and improves dry skin. Broccoli, scientifically known as Brassica oleracea L, is rich in vitamin C components, vitamin E (α-tocopherol), and flavonoids, which act as natural antioxidants and provide moisturizing properties for the skin. Producing extracts by the maceration process. Broccoli extract is utilized in the formulation of four moisturizing cream preparation compositions, each with a concentration of F1 (0%), F2 (2%), F3 (3%), and F4 (4%). The moisturizing cream formulation is assessed for its physical properties. Conducting tests to evaluate the dosage characteristics of moisturizing creams, includes organoleptic testing, homogeneity testing, pH testing, dispersion testing, adhesion testing, and viscosity testing. The concentration of broccoli extract in the four moisturizing cream preparation formulations is as follows: F1 (0%), F2 (2%), F3 (3%), and F4 (4%). The moisturizing cream formulation is assessed for its physical properties. Conducting tests to evaluate the dosage properties of moisturizing creams, including sensory evaluation, uniformity assessment, pH measurement, dispersion analysis, adhesion examination, and viscosity measurement
AN ANALYSIS OF FLAVONOID COMPOUNDS FROM ETHANOL EXTRACT OF MORINGA LEAVES (MORINGA OLEIFERA L.) USING FTIR AND HPLC Puruhita, Ranatri; Sulistyoningsih, Danik; Kristiyanti, Winnie; Aulia Rachma, Firstca
Science and Community Pharmacy Journal Vol. 3 No. 2 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i2.583

Abstract

Moringa leaves contain flavonoids, phenols, tannins, alkaloids, saponins, terpenoids, and steroids. The flavonoid and phenol content has antioxidant activity. This research aimed to determine compounds in the ethanol extract of Moringa leaves To determine the type of flavonoid content using FTIR and HPLC. FTIR analysis shows that Moringa leaves possibly contain compounds from quercetin derivatives, which is supported by HPLC analysis. This quercetin compound is a group of flavonols that are characterized by the presence of a hydroxyl group and a carbonyl group. HPLC analysis was carried out by making a quercetin standard with a concentration of 200 ppm. The resulting wavelength is 254 nm. The results of the quercetin standard chromatogram which contains one main peak obtained from the quercetin standard. This peak shows the retention time at 3 minutes. The results of the standard chromatogram, quercetin has an outer area of ​​44763473 and a sample area of ​​17455781 with 2 times dilution, so the % purity of fraction 9 for quercetin is 77.99 ppm. This HPLC analysis shows that Moringa leaves probably contain quercetin derivatives which are characterized by the same retention time between the sample and the quercetin standard, namely at a retention time of 3 minutes, and have a peak pattern that is almost the same as the quercetin standard.
EFEKTIVITAS PENYEMBUHAN LUKA BAKAR AKIBAT PEMBERIAN GEL ESTRAK ETANOL DAUN CENGKEH (Syzygium aromaticum L.) PADA KELINCI (Oryctolagus cuniculus) Puruhita, Ranatri; Aldila, Silvy; Ariyani, Destiana Putri
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p221-228

Abstract

Burns are damage to the organs that can happen when heat exposure from fire, chemicals, electricity, or radiation damages or destroys skin tissue. For burns, topical treatment can hasten the healing process. Because clove leaves have antiseptic qualities and antibacterial and anti-inflammatory activity, their secondary metabolites—flavonoids, tannins, and saponins—can be used to treat open wounds and stop infection. The purpose of this study is to create a gel formulation using clove leaf extract that will treat burn wounds without causing skin infections. Two formulations of the gel preparation, each with a 10% and 15% concentration, were evaluated on test rabbits. Using a hot iron plate, the rabbits' backs were shaved to cause burns. Clove leaf extract gel was used for the treatment group, Bioplacenton® was used as the positive control, and gel base was used as the negative control. Measurements of the wound's diameter were taken on days 0 and 15, and SPSS was used to analyze the results. Clove leaf extract burn gel is 60.98% effective in formula 1 and 77.16% effective in formula 2. Formula 2 is the gel formulation that works best for treating rabbit burns.
Pengaruh Berat Badan Terhadap Efek Aprodisiaka pada Mencit dengan Pemberian Jus Buah Nanas Madu Puruhita, Ranatri; Hesti Wulan S, A. Ariani; Puspitaningrum, Ika
Jurnal Farmasi (Journal of Pharmacy) Vol. 9 No. 2 (2020): Jurnal Farmasi (Journal of Pharmacy), October 2020
Publisher : Jurnal Farmasi (Journal of Pharmacy)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Afrodisiaka adalah suatu bahan organik, minyak esensial (minyak atsiri), obat, minuman herbal atau bahan yang dapat membangkitkan gairah seksual. Penelitian ini menggunakan jus buah nanas madu (Ananas comosus L.Mer). Parameter yang akan dilihat yaitu pengaruh berat badan dan kemampuan daya aprodisiaka meliputi introduction, climbing, dan coitus. Hewan uji terbagi dalam 5 kelompok perlakuan yaitu kelompok I normal, kelompok II diberikan jamu pasak bumi®, kelompok III diberikan jus buah nanas 30g/KgBB mencit, kelompok IVdiberikan jus buah nanas 45g/KgBB mencit, dan kelompok V diberikan jus buah nanas 67,5g/KgBB mencit. Pemberian dilakukan selama 14 hari secara per oral dengan frekuensi pemberian sehari satu kali pada control positif dan pada kelompok pemberian jus sebanyak dua kali sehari. Pada hari ke-15 dilakukan pengamatan terhadap berat badan, berat testis dan aktifitas aprodisiak meliputi introduction, climbing, dan coitus. Berdasar hasil statistic dosis efektif jus buah nanas madu adalah 45g/KgBB dan tidak terdapat hubungan antara berat badan dan kemampuan aprodisiaka.
Co-Authors Aldila, Silvy Ariyani, Destiana Putri Aulia Rachma, Firstca Gloria, Fransisca Hesti Wulan S, A. Ariani Ika Puspitaningrum Kristiyanti, Winnie Sa’adah, Anifatus Sulistyoningsih, Danik Uliana, Syahkhirotul Exma