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All Journal JFM (Jurnal Farmasi Malahayati) Jurnal Pengabdian Masyarakat Bangsa PharmaCine : Journal of Pharmacy, Medical and Health Science Warta LPM Indonesian Journal of Cosmetics
Handayani, Kiki Yuli
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Program Peningkatan Kesadaran Kesehatan Kulit pada Kelompok PKK di Kecamatan Way Tuba, Way Kanan, Lampung Fahmi, Achmad Gus; Suryaneta; Handayani, Kiki Yuli; Putri, Tikarahayu; Sari, Indah Puspita; Auli, Winni Nur
Warta LPM WARTA LPM, Vol. 26, No. 4, Oktober 2023
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/warta.v26i4.1733

Abstract

Way Tuba sub-district, Way Kanan is one of the areas where the majority of people work as farmers. This profession is very vulnerable to direct sunlight exposure which has a negative impact on human health, especially the skin and eyes. The worst danger due to UV exposure that most often occurs is Non-Melanoma Skin Cancer (NMSC). Awareness of these dangers is still not fully understood by the community, so a program is needed that can increase understanding of the risks of direct sun exposure and skin health. Lecturers of the Cosmetic engineering, ITERA organized a program to increase skin health awareness through several activities such as counseling for PKK groups, training in making simple skin care from natural ingredients around the house and initiating the planting of a family cosmetic garden in the yard. Utilization of natural ingredients around the house can overcome skin damage at a low cost. In addition, with the cultivation of plants that maintain skin health in the home yard, it can be used at any time as prevention not just as treatment. Therefore, it is necessary to understand the types and ways of using natural ingredients around the house for the community, especially the PKK Group as a driving cadre in each village. Based on the results of the questionnaire, this community service program can increase community understanding up to 90% of representatives from 13 PKK groups in each village in Way Tuba District. Some plants were also cultivated directly through the initiation of a family cosmetic garden in one of the residents' yards. This is expected to be a trigger for other PKK groups in utilizing yard land in caring for skin health.
Minimalisasi Biaya Obat Antihipertensi Lisinopril Atau Candesartan Pada Pasien Hipertensi Disertai Gagal Ginjal Kronik Di Instalasi Rawat Inap RSUD Dr. H. Abdul Moeloek Septiani, Anastya Devi; Rooswita, Putri Amelia; Handayani, Kiki Yuli
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 5 No 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.11239

Abstract

Hypertension can damage blood vessels, which if not handled properly can cause kidney damage. Chronic Kidney Disease (CKD) is the most common comorbid in hypertensive patients in Indonesia with a percentage of 51%. The successful treatment of hypertension accompanied by CKD can be supported by administration of antihypertensives. The variety of antihypertensive therapy alternatives makes pharmacoeconomic studies necessary in order to obtain cost-effective therapy. The purpose of this study was to find out which antihypertensive drug is the most cost-minimizing between lisinopril and candesartan used in the treatment of hypertension accompanied by CKD (ICD-10 I12.0) in the Inpatient Installation based on the perspective of RSUD Dr. H. Abdul Moeloek in 2022. This research is a non-experimental observational with a purposive sampling technique. Data collection was carried out retrospectively from tracking secondary data originating from medical records, drug details in the Hospital Information System (SIRS), and details of direct medical costs in the Hospital Finance Department. Costs collected are in the form of direct medical costs which include antihypertensive drug costs, supporting drug costs, accompanying drug costs, laboratory costs, ICU, emergency room, hemodialysis, and hospitalization. The study showed that the average total cost of treating antihypertensive therapy for lisinopril was higher than candes artan, with lisinopril amounting to Rp 3.778.163 while candesartan was Rp 3.307.740. These results indicate that use of the antihypertensive candesartan is more cost-minimizing compared to lisinopril with a saving value of IDR Rp 470.423. Keywords: Pharmacoeconomics; CMA; hypertension with CKD; lisinopril; candesartan
Community Empowerment through Pala Waste Utilization: Ecoenzymes, Syrup, and Candied Nutmeg in Paya Village, Pesawaran District Yasir, Angga Saputra; Suryaneta, Suryaneta; Sari, Indah Puspita; Putri, Tikarahayu; Handayani, Kiki Yuli
Jurnal Pengabdian Masyarakat Bangsa Vol. 1 No. 9 (2023): November
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v1i9.431

Abstract

This community engagement initiative unfolds in Paya Village, located in the Padang Cermin Subdistrict, Lampung Province, Indonesia. With a population of 1,190 individuals distributed across four hamlets, the village predominantly thrives on daily labor and agriculture, with nutmeg as a prominent crop. Organic waste generated from nutmeg fruit, particularly the husks and flesh, has been largely underutilized. This initiative, led by the PKK group, endeavors to empower the community, enhance household incomes, and address the issue of organic waste accumulation by converting nutmeg waste into value-added products. The program focuses on creating eco-enzymes, nutmeg syrup, and candied nutmeg. Capacity-building activities are central to this initiative, involving workshops, training, and educational programs. Regular evaluations highlight the program’s success in enhancing participants’ knowledge and awareness of nutmeg products.
FORMULATION AND EVALUATION OF EAU DE PARFUME (EDP) FLORAL AROMA CHARACTERISTICS Putri, Tikarahayu; Handayani, Kiki Yuli; Reza, Muhammad
Indonesian Journal of Cosmetics Vol. 1 No. 1 (2023)
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/ijcos.v1i1.1634

Abstract

Currently, perfumes have emerged as highly sought-after cosmetic products in the Indonesian consumer market, aligning with the demands of daily life for enhanced self-assurance. Various types of perfume are categorized based on the ratio of fragrant oil content to solvent. Presently, the prevailing perfumes available in the market predominantly belong to the category with low concentrations of fragrant oils. The principal objective of this research is to formulate a product recipe for Eau de Perfume (EDP) with sweet and floral characteristics. The methodology employed in this study is experimental and consists of two phases: perfume formulation, evaluation, and final product development. The evaluation conducted in this research encompasses organoleptic and physical assessment, aroma longevity testing, spot testing, hedonic evaluation, and sensory testing. Based on the data collected from the research results, it can be concluded that the perfumes with longer aroma longevity are formulas F1 and F2. The average area of EDP spray dispersion is 74,48 mm. The most preferred hedonic test result was obtained from formula F2. Organoleptic test data for all formulas showed a clear and particle-free, the colorless solution observed after one month of storage. The solution’s viscosity increased during the fourth week due to the partial evaporation of the solvent. Sensory analysis results revealed that the aroma of all three formulas was characterized as sweet with floral undertones.
STABILITY AND IRRITATION TESTING USING THE PATCH TEST METHOD OF A COMBINATION GEL FORMULATION CONTAINING ALOE VERA AND BASIL LEAF EXTRACTS Yasir, Angga Saputra; Suryaneta, Suryaneta; Handayani, Kiki Yuli; Satria, Bagus
Indonesian Journal of Cosmetics Vol. 1 No. 1 (2023)
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/ijcos.v1i1.1638

Abstract

Aloe vera and basil leaves have been recognized for their anti-inflammatory and antibacterial properties. Combining these extracts into a gel formulation offers convenience in application. However, research concerning potential irritations associated with its use remains limited. This study aims to assess irritation in humans resulting from the application of a gel formulation containing basil and aloe vera extracts using patch testing. The gel formulation is prepared with a 2% concentration of the extracts, with a 1:1 ratio of basil to aloe vera extracts. Optimization is achieved by varying carbopol concentrations and the final pH of the gel formulation. The parameters used for determining the optimal formula include organoleptic characteristics, viscosity, spreadability, adhesiveness, and pH of the formulation. The optimal formula is subsequently subjected to stability testing over four weeks and irritation testing using patch methods. A total of 25 volunteers are involved in the irritation testing. Observations are made up to 72 hours after the removal of the formulation to ensure the absence of delayed irritation effects. Aloe vera and basil extractions using ethanol as a solvent yield sequential yields of 1.7% and 3%, respectively. Quality evaluation for Formulations I (FI), II (FII), and III (FIII) includes spreadability, adhesiveness, and viscosity, as follows: (4.1 cm; 5.4 seconds; 5504 mPa.s); (6.5 cm; 4.1 seconds; 3480 mPa.s); and (5.2 cm; 4.2 seconds; 6340 mPa.s), respectively. FII is selected as the optimal formula because it exhibits wider spreadability and lower viscosity compared to FI and FIII (P <0.05). Stability testing for FII shows that the formula remains stable during storage for all quality testing parameters (P > 0.05). The Primary Irritation Index (PII) for FII has a value of 0.0216, indicating that it does not cause irritation during patch testing.
THE IDENTIFICATION OF BIOACTIVE COMPOUNDS IN BUTTERFLY PEA (Clitoria ternatea L.) FLOWER SIMPLICIA: A MACROSCOPIC, MICROSCOPIC, AND PHYTOCHEMICAL STUDY Elianasari, Elianasari; Herayati, Herayati; Handayani, Kiki Yuli; Astuti, Puput Puji
Indonesian Journal of Cosmetics Vol. 2 No. 2 (2024): Indonesian Journal of Cosmetics
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/ijcos.v2i2.2059

Abstract

The butterfly pea flower (Clitoria ternatea L.) is known for its distinctive purple petals. This plant typically grows as an ornamental and can be used as a natural eye remedy and food coloring, safe for human consumption. This study aims to investigate the characteristics and perform a phytochemical screening of the butterfly pea flower (Clitoria ternatea L.). The characteristics of the flower simplicia were examined through macroscopic and microscopic observations, followed by a phytochemical screening process, which included testing for alkaloids, flavonoids, saponins, tannins, and terpenoids/steroids using specific reagents. Additionally, non-specific characteristics, such as moisture content, were analyzed. The results indicate that the flower simplicia has a distinct odor, is tasteless, blue in color, and appears in a dry form. Microscopically, the flower simplicia revealed single grains and thin slices, showing epidermal cell fragments with stomata and crystal fibers with vascular bundles. The phytochemical screening confirmed the presence of alkaloids, saponins, and flavonoids, while tannins and terpenoids/steroids were absent.
Formulasi dan Uji Stabilitas Fisikokimia Masker Rambut Emulsi O/W kombinasi Aloe vera, Chamomile, dan Hyaluronic acid Handayani, Kiki Yuli; Agustina, Dina Putri
JFM (Jurnal Farmasi Malahayati) Vol 8, No 2 (2025)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v8i2.21895

Abstract

Kesadaran konsumen yang semakin tinggi terhadap gaya hidup sehat dan penggunaan bahan alami mendorong pertumbuhan pesat pada sektor kosmetik fungsional, termasuk produk perawatan rambut yang salaah satu jenisnya adalah masker rambut. Penelitian ini bertujuan untuk merancang suatu formula dan mengevaluasi stabilitas fisikokimia dari produk masker rambut dalam bentuk emulsi Oil in Water (O/W) dengan kombinasi bahan aktif ekstrak Aloe vera, chamomile, dan hyaluronic acid (HA). Ketiga bahan tersebut dipilih untuk dikombinasikan karena berdasarkan studinya masing-masing manfaatnya telah terbukti masing-masing bahan telah terbukti manfaatnya dan memiliki efek sinergis dalam melembapkan, menenangkan kulit kepala, serta meningkatkan elastisitas dan hidrasi rambut. Formulasi dilakukan menggunakan teknik emulsifikasi, dan selanjutnya produk masker diuji secara organoleptik kemudian dilanjutkan pengujian fisikokimia sediaan meliputi uji pH, viskositas, dan stabilitas fase yang diuji dengan metode uji stabilitas dipercepat. Hasil menunjukkan bahwa produk masker rambut memiliki warna putih konsisten, ukuran partikel yang homogen, aroma lembut, pH 5,6, dan nilai viskositas 33.000cps. Pemisahan fase tidak ditemukan selama uji stabilitas, hal ini menunjukkan kestabilan yang baik. Tantangan pendispersi HA berhasil diatasi melalui penerapan teknik pelarutan bertahap dalam medium air hangat sebelum emulsifikasi. Hasil studi ini menunjukkan bahwa kombinasi Aloe vera, chamomile, dan HA dapat diformulasikan menjadi suatu produk masker rambut alami yang stabil dan aman untuk dikembangkan lebih lanjut sebagai produk perawatan rambut.
Co-Authors Agustina, Dina Putri Angga Saputra Yasir Astuti, Puput Puji Elianasari Fahmi, Achmad Gus Herayati, Herayati Indah Puspita Sari Muhammad Reza Putri, Tikarahayu Rooswita, Putri Amelia Satria, Bagus Septiani, Anastya Devi Winni Nur Auli