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All Journal HIGIENE: Jurnal Kesehatan Lingkungan Pharmacon: Jurnal Farmasi Indonesia
Hansur, Lismayana
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Environmental Science Health Professions Medicine & Pharmacology Public Health

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Potential of Hydroxysafflor yellow A, the main compound of Kasumba Turate (Carthamus tinctorius ) as Anti-Inflammatory in Lung, Liver and Cardiac Tissues: A Literature Review Hansur, Lismayana; Aras, Dara Ugi; Endah Dwijayanti
Pharmacon: Jurnal Farmasi Indonesia Volume 21, No 2 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i2.4908

Abstract

Inflammation is the body's physiological response to stimuli such as infection, trauma and chronic disease. Its exacerbation can lead to deterioration in health and damage to tissues in organs such as the lungs, kidneys and liver. The drive behind the development of anti-inflammatory drugs is to improve treatment efficacy and reduce adverse effects. The primary aim of this article is to deliberate on the pharmacological properties of compound from C.tinctorius as an anti-inflammatory agent. Through an extensive study of data we made a literature review of 17 research conducted to unravel the potential of compound from C.tinctorius as an anti-inflammatory agent. The ability of Carthamus tinctorius to alleviate inflammation is demonstrated by its ability to inhibit the activation of the NF-κB pathway and suppress the binding of the TGF-β1 promoter. These molecular processes hold the promise of ameliorating lung injury by attenuating the inflammatory response through suppression of the TLR 4-dependent signalling pathway, thereby improving the health of rats suffering from pulmonary fibrosis, a condition characterised by inflammation and vascular tissue repair. In addition, compounds in C. tinctorius are effective in reducing T lymphocyte (CD4) apoptosis in sepsis through their anti-inflammatory and anti-apoptotic effects. The anti-inflammatory mechanism is also demonstrated by reducing inflammatory cytokines such as IL-6 in the lungs, kidneys and liver.
Tingkat Kecemasan Mahasiswa Tingkat Akhir Dalam Menghadapi Tugas Akhir Karya Tulis Ilmiah (KTI) Di Akademi Keperawatan Yapenas 21 Maros Nurmasita, Nurmasita; Sakriawati, Sakriawati; Wahyuningsih, Sri; Hansur, Lismayana; Bin Laeto, Arwan
HIGIENE: Jurnal Kesehatan Lingkungan Vol 10 No 3 (2024): Kesehatan Lingkungan
Publisher : Public Health Department, Universitas Islam Negeri Alauddin Makassar

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Abstract

The final project is one of the main requirements for studenst to obtain a graduation degree. However, some students are not psychologically prepared to face it, leading to anxiety disorders. Anxiety is a state that can cause someone to feel uncomfortable, restless, afraid, worried, and uneasy, accompanied by various physical symptoms. anxiety also refers to a person's subjective feelings of tension, fear, nervousness, and worry. The high level of anxiety makes a person's normal life difficult, such as disrupting activities and social life. Anxiety is one of the various types of emotional and behavioral disorders. The purpose of this research is to determine the Description of the Anxiety Level of Final Year Students in the D-III Nursing Education Program. This research method uses Descriptive Quantitative with a population of all final-year students from the 2022 cohort at the Yapenas 21 Maros Nursing Academy campus. The research results show that the majority of respondents experienced moderate anxiety levels at 60%, students who experienced mild anxiety levels at 26.7%, and students who experienced severe anxiety levels at 13.3%. It can be concluded that the majority of final-year students from the 2022 cohort of the D-III Nursing Education program at the Yapenas 21 Maros Nursing Academy are at a moderate level when facing their final scientific writing task (KTI).
Co-Authors Aras, Dara Ugi Arwan Bin Laeto Endah Dwijayanti Nurmasita, Nurmasita Sakriawati, Sakriawati Sri Wahyuningsih