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All Journal Universa Medicina Medicinus : Jurnal Kedokteran
Kristiani, Erna
Faculty Of Medicine, Pelita Harapan University
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Relationship of Sexual Violence to Depression in Female Students of Faculty of Medicine, Pelita Harapan University Xaviera, Luqyana Ghina; Kristiani, Erna; Suryadinata, Neneng
Medicinus Vol. 12 No. 2 (2023): February
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v10i3.7035

Abstract

Background: Sexual violence can take many forms to anyone. The increase in the number of sexual violence against women in Indonesia is quite significant. These incidents are reported to occur frequently in women in young adulthood. These experiences can have long-term effects, one of which is depression. There are several studies that show an association between sexual violence and the incidence of depression. However, there has not been much quantitative research to look at the relationship on this matter in Indonesia, especially on female students. This study aims to understand the relationship between sexual violence and the incidence of depression in female students of the Faculty of Medicine, Universitas Pelita Harapan.Methods: This study use a cross-sectional study design. The data has been collected using questionnaires filled in by the respondents. This study involved 149 female students of the Faculty of Medicine, Pelita Harapan University. The results of the study were processed and statistically analyzed using SPSS 25.Result: Based on research data, there are 149 respondents from female students of the Faculty of Medicine, Universitas Pelita Harapan. with a mean age of 19.29 (SD = 1.086). The youngest age of the respondent is 17 years old and the oldest is 24 years old. A total of 55 respondents had experienced sexual violence. Based on the results of the Beck's Depression Inventory (BDI) questionnaire, 16% had mild depression, 9% had moderate depression, and 2% had severe depression. Chi-square test showed a significant relationship between experiences of sexual violence and the incidence of depression, with p <0.001.Conclusions: Sexual violence is related to the incidence of depression in female students of the Faculty of Medicine, Pelita Harapan University.
Relationship Between Clinical Factors of Lymphoma DLBCL GCB and Non-GCB Subtype with Ki-67 Proliferation Index in Siloam Karawaci Hospital 2014 - 2018 Kristiani, Erna; Marisca, Stephanie; Qurro, Tri Ulfatul; Kweeswara, Natasya; Chandra, Amos Immanuel
Medicinus Vol. 12 No. 3 (2023): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v11i1.7365

Abstract

Background: Non-Hodgkin large cell B-lymphoma (DLBCL: Diffuse Large B-cell Lymphoma) were classified into two subtypes of Germinal Center B-Cell Like (GCB) and non-Germinal Center B-Cell Like (non-GCB), which GCB has a better prognosis. The Ki-67 antigen is one of the most reliable markers of cell proliferation. This research aims to establish the relationship between proliferation index Ki-67 with DLBCL subtypes and to evaluate the utility of Ki-67 proliferative index as a predictive marker for predicting stages of lymphoma.Methods: We obtained 60 cases of patient samples DLBCL in Siloam Hospital Lippo Karawaci in 2014-2018. Clinical and pathological data were obtained from medical records. Chi-square methods were used to analyze data.Result: There were more ‰¤60 years compared to >60 years. In this study, there were more male patients than female patients. lymphoma provided in extranodal were higher than lymphoma in nodal form.Conclusions: There is a relationship between Ki-67 proliferation index with lymphoma GCB and non-GCB subtypes and stage of lymphoma, which can be used as a predictive factor in predicting the stage of lymphoma.
Prognostic factors of brain metastases affecting survival: an Indonesian cohort Koesbandono, Koesbandono; Muljadi, Rusli; Sutanto, Ratna; Hendriansyah, Lutfi; Kristiani, Erna; Faustina, Carissa; Christanti, Jessica
Universa Medicina Vol. 44 No. 3 (2025): Ahead Of Print
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2025.v44.298-309

Abstract

BackgroundBrain metastases (BMs) most frequently originate from primary tumors of the lung and breast, and significantly impact cancer patient prognosis. Metastases can be detected synchronously along with the primary tumor or metachronously, following treatment of localized disease. The objective of this study was to identify key prognostic factors influencing survival in synchronous metastases (SM) and metachronous metastases (MM), focusing on metastatic duration, tumor volume response, and gamma knife radiosurgery. MethodsA retrospective cohort study was conducted involving 100 patients with brain metastases (48 synchronous, 52 metachronous). Age, gender, primary tumor, gamma knife status, metastasis location, peritumoral index group, volume reduction, metastatic duration, metastasis characteristics, and intensity pattern based on MRI. A Cox proportional hazards regression was used to analyze the data. Based on the Cox regression coefficients, a prognostic index was constructed. ResultsCalculated HR comprised MM (HR=0.49;95% CI :0.24–0.97], gamma knife treatment (HR = 0.15;95% CI: 0.07–0.29], and volume response (HR=0.40;95% CI: 0.16–0.99), all indicating a significantly reduced mortality risk. A prognostic index was calculated for all patients; those with scores ≤–1.513 were classified as low risk. Kaplan-Meier analysis showed that the low-risk group had a significantly longer mean survival period (75.52 months) compared to the high-risk group (31.43 months) (p<0.001). ConclusionMetachronous presentation, gamma knife therapy, and greater tumor volume reduction independently predict better survival. The developed prognostic index provides a clinically useful tool for personalized risk assessment and treatment planning in patients with brain metastases.
Co-Authors Agelica, Michelle Baskoro, Bernard A. Benyamin Makes Bernard A. Baskoro Chandra, Amos Immanuel Dermawan, Kevin Devita Widjaja Dharmawan, Kevin Dwinovitch, Febrihardita Faustina, Carissa Febrihardita Dwinovitch Harahap, Agnes S. Helenia Putri Hendriansyah, Lutfi Jessica Christanti Julius July Kevin Dharmawan Koesbandono, Koesbandono Kristina, Maria A. Kweeswara, Natasya Luqyana Xaviera Maria A Kristina Maria F. Ham Marisca, Stephanie Michelle Agelica Nadya Aisyah Widowati Neneng Suryadinata Putri, Helenia Qurro, Tri Ulfatul Rusli Muljadi Rusli Muljadi, Rusli S Harahap, Agnes Sally Suharyani SR Hardjolukito, Endang Suharyani, Sally Suryadinata, Neneng Susanto, Eka Sutanto, Ratna Tjahjadi, Hartono Widjaja, Devita Widodo, Stephanie T. Widowati, Nadya Aisyah Xaviera, Luqyana Ghina