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All Journal Jurnal Kedokteran Brawijaya Syntax Literate: Jurnal Ilmiah Indonesia JURNAL AKUNTANSI KEUANGAN DAN MANAJEMEN Dinasti International Journal of Economics, Finance & Accounting (DIJEFA) Indonesian Journal of Industrial Engineering & Management Jurnal Klinik dan Riset Kesehatan Jurnal Locus Penelitian dan Pengabdian Jurnal Ilmiah MEA (Manajemen, Ekonomi, dan Akuntansi)
Arviansyah, Arviansyah
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Aerospace Engineering Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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The Effectiveness of Silicon Wound Dressing for the Healing Process of Contaminated Abrasions Limpat Wihastyoko, Herman Yosef; Siswoyo, Devira; Arviansyah, Arviansyah; Siswanto, Yudi; Agustina, Wilma; Sintaningrum, Elisabeth Prajanti
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.16

Abstract

Wounds are skin disorders caused by pathological processes. Abrasion wounds are a type of acute injury. One of the contributing factors is traffic accidents. More than 1.2 million people died as a result of traffic accidents, while 20-50 million others suffered injuries. Choosing the proper dressing can determine wound healing. This case study aims to determine the effectiveness of silicone wound dressing in the healing process of contaminated abrasion wounds. Contaminated abrasion wounds are contaminated by dirty materials, which potentially cause infection. This case report describes four patients, Mrs. W, Mrs. K, Mr. Y, and Mr. M., who suffered abrasions on the face. Their wounds were cleaned in the operating room under general anesthesia. A silicone wound dressing is applied as the primary dressing. The secondary dressing depends on the amount of the exudate. On the 3rd day after the surgery, the wounds looked dry, so they were cleaned and reapplied with the silicone dressing. On the 7th day, after applying silicone wound dressing, the wound had epithelialized. Silicone wound dressing is a modern type of dressing that is effective for acute wounds as it provides a barrier against external contamination. Our sample shows that wound are abrasion contaminated. The result of silicone wound dressings applied was shown accelerate the wound healing process. Modern dressings accelerate wound healing 20% to 40% faster than conventional dressings, such as gauze, tulle, or gauze.  
How Substantial is the Effect of Polyhexamethylene Biguanide (PHMB) Irrigation Solution on a Wound's Biofilm? Tanaka, Ferdian; Sandakh, Shaza Nathasya; Hananto, Geovan; Pamuji, Maurin A.; Arviansyah, Arviansyah
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 12 (2025): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i12.4982

Abstract

Background: Biofilm as a key component that contributes to the development of chronic wounds can increase the resistance of bacteria to antiseptic solutions. The current standard procedure for wound care involves the use of wound cleansing solutions such as povidone-iodine, chlorhexidine, and normal saline. Each of these solutions has limitations. One of the newer wound cleansing solutions is Polyhexamethylene Biguanide (PHMB). PHMB is known to inhibit the formation and disrupt the structure of biofilm. This study aims to conduct a systematic review and meta-analysis to evaluate the effectiveness of using PHMB as a wound irrigation solution in reducing biofilm in wounds. Methods: PubMed, Mendeley, ScienceDirect, and Cochrane were used as a database using the keywords for the analysis . Further exclusion using PICO criteria left us with  5 studies that met the inclusion criteria. Results: Our findings demonstrated a significant improvement in irrigation with PHMB group compared to the control group (MD= -5.09, 95% CI -8.40 to -1.78, p= 00001, I2= 99%,), there was significant biofilm reduction with the PHMB group compared to the control group (RD= 0.74, 95% CI 0.56 to 0.91, p= 00001, I2= 0%). Conclusion: Compared to standard wound irrigation solutions, PHMB presents several advantages. It acts as a potent bactericidal agent against biofilm-forming microbes, including both Gram-positive (Staphylococcus aureus and MRSA) and Gram-negative bacteria (Pseudomonas aeruginosa). Additionally, PHMB is effective against fungi (Candida albicans), does not induce pain, and is non-toxic to healthy cells and granulation tissue.
Co-Authors Agustina, Wilma Almadita, Teresa Arifin, Zanuar Badawi, Yessica Tania. H Del Rosario Puling, Imke Maria Hananto, Geovan Limantara, Jane Limpat Wihastyoko, Herman Yosef Nastiti, Sandra Pamuji, Maurin A. Pramana Giri, Nyoman Deva Putra, Rafif Eka Sandakh, Shaza Nathasya Santoso, Anton Sintaningrum, Elisabeth Sintaningrum, Elisabeth Prajanti Siswoyo, Devira Tanaka, Ferdian Wahyudi, Novan Wihastyoko, Herman Wihastyoko, Herman Yosef Limpat Wruhastanti, Gisella S. Yudi Siswanto