Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Padjadjaran Journal of Dentistry Journal of Indonesian Dental Association
Kiranahayu, Rarasih
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Association of rs235768 A>T polymorphism of the bone morphogenetic protein 2 gene on non-syndromic orofacial cleft in an Indonesian population Kiranahayu, Rarasih; Suhartono, Antonius Winoto; Sulistyani, Lilies Dwi; Latief, Benny Sjariefsjah; Auerkari, Elza Ibrahim
Padjadjaran Journal of Dentistry Vol 32, No 2 (2020): July 2020
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol32no2.23917

Abstract

Introduction: Orofacial cleft is one of the many congenital malformations that often occur in human, leaving it at the fourth level of the most common orofacial birth defect findings. The incident rate is one in 700-1000 deliveries, where without therapeutic and surgical interventions, children with an orofacial cleft may have problems with speech, nutrition intake, and growth. Bone morphogenetic protein 2 (BMP-2) gene play essential roles in the migration and proliferation of neural crest cell of the early head formation and regulate mineralised tissues such as maxillary, mandible, palate and teeth. This study was aimed to analyse the BMP-2 polymorphism and its potential association with orofacial cleft in an Indonesian population. Methods: Cross-sectional study was conducted towards 128 samples, 32 samples of orofacial cleft patients and 96 samples of control. Extracted genotype and allele was determined with PCR-RFLP method using stored DNA samples from 32 orofacial cleft patients, and 96 healthy control. Results: The TT genotype was showing the p-value = 0.001, OR = 2.43% in orofacial samples (71.4%), which was significantly higher than in control groups (28.6%). The allele distribution was also considered statistically significant (p = 0.036, OR =1.89%. Conclusion: There is a significant association of rs235768 A>T polymorphism of the BMP-2 gene on non-syndromic orofacial cleft patients in Indonesia.
Curettage Treatment on Stage III and IV Periodontitis Patients Harsas, Nadhia Anindhita; Safira, Dhia; Aldilavita, Hanli; Yukiko, Ingetiarani; Alfarikhi, Mochamad Prabu; Saadi, Muhammad Tsany; Feria, Qonita; Kiranahayu, Rarasih; Muchlisya, Shabrina
Journal of Indonesian Dental Association Vol 4 No 1 (2021): April
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Periodontitis is an inflammatory disease of teeth supporting tissue caused by a group of specific microorganism that causes progressive damage to the periodontal ligament and alveolar bone. Periodontal pocket is one of the most important clinical features of periodontal disease. This case report aims to evaluate the results of curettage in periodontitis cases with different stages and grades. Case reports: This report consists of two cases. The first case is a 41-year-old female patient with a chief complaint of gum bleeding during brushing and tooth mobility. Intraoral examination showed gingival redness and swelling, positive papillary bleeding index (PBI) in all regions, and an OHI-S score of 3.16 (poor). A probing depth of 4-5 mm was present on the upper right canine and the lower left central incisor. Gingival recession of 1 mm was also present on the upper right canine. Radiographic examination showed horizontal bone defect that reached the cervical third of the root on the upper right canine and the middle third of the root on the lower left central incisor. The second case is a 61-year-old female patient with a chief complaint of tooth hypersensitivity and tooth mobility since three years ago. Intraoral examination showed gingival redness and swelling with positive PBI in all regions. Oral Hygiene Index- Simplified (OHI-S) score was 3.6 (poor). A probing depth of 4-5 mm and gingival recession was present on both lower left incisors. Grade 1 tooth mobility was also present on the lower left central incisor. Radiographic examination showed horizontal bone defect reaching the apical third of the root. Curettage was performed for both cases after a thorough scaling and root planing. Conclusion: Curettage as a treatment for patients with chronic periodontitis after 4 weeks shows an improvement of patient’s Oral Hygiene Index - Simplified (OHI-S) score and reduced probing depth.
Co-Authors Aldilavita, Hanli Alfarikhi, Mochamad Prabu Antonius Winoto Suhartono, Antonius Winoto Elza Ibrahim Auerkari Feria, Qonita Harsas, Nadhia Anindhita Latief, Benny Sjariefsjah Muchlisya, Shabrina Saadi, Muhammad Tsany Safira, Dhia Sulistyani, Lilies Dwi Yukiko, Ingetiarani