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All Journal Health and Medical Journal Nusantara Hasana Journal
Hansah, Rendri Bayu
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Effects of Vitamin D Supplementation on Blood Glucose Levels in Streptozotocin-Induced Diabetic Rats Hansah, Rendri Bayu; Dhuha, Alief; Susanti, Melya; Sari, Widia; Khudri, Ghaniyyatul; Handayani, Kurnia Maidarmi
Health and Medical Journal Vol 7, No 2 (2025): HEME May 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i2.1717

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia due to impaired insulin secretion, insulin resistance, or both. Poor glycemic control in DM leads to complications such as cardiovascular disease and nephropathy. Vitamin D has been suggested to influence glucose metabolism by improving insulin secretion and sensitivity thorugh mechanisms involving pancreatic β-cells and anti-inflammatory pathways. This study evaluates the effect of vitamin D supplementation on blood glucose levels in diabetic rats. An experimental study was conducted using 25 males Sprague Dawley rats, divided into five groups: Group A (negative control), Group B (non-DM + 415 IU/kgBW vitamin D), Group C (DM without vitamin D), Group D (DM + 415 IU/kgBW vitamin D), and Group E (DM + 1100 IU/kgBW vitamin D). Diabetes was induced using streptozotocin (50 mg/kg BW), and rats with random blood glucose levels >200 mg/dL were considered diabetic. Vitamin D supplementation was given via gavage for 30 days. Serum vitamin D and random blood glucose levels were measured 30 days after supplementation. Statistical analyses included ANOVA and Pearson correlation tests. Vitamin D supplementation significantly increased serum vitamin D levels in diabetic rats, especially in Group E (DM + 1100 IU/kgBW vitamin D; (p < 0.05). Random blood glucose levels decreased significantly in diabetic groups and Group E showed the largest glucose reduction (p < 0.001). A moderate negative correlation (r = -0.47, p = 0.017) between vitamin D levels and glucose changes was observed. Vitamin D supplementation reduces blood glucose levels in diabetic rats, with higher doses showing greater efficacy. These findings highlight vitamin D’s potential as an adjunctive therapy for diabetes management. Further research is needed to explore underlying mechanisms.
PENYULUHAN PENCEGAHAN DEMAM BERDARAH DENGUE (DBD) DI MASJID DARUL MUTTAQIN KOTA PADANG Suharni, Suharni; Erdanella Setiawati; Rosmaini, Rosmaini; Hansah, Rendri Bayu; Yanti Fitri Yasa; Shafira Larissa; Muhammad Alfan Syuri Asqa; Relly Angelica Putriz; Sahla Riska Nafiah; Atika Karina Asmi; Gangga Mahatma
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1836

Abstract

Dengue Hemorrhagic Fever (DHF) is a public health problem in Indonesia, particularly during the rainy season when the population of Aedes aegypti mosquitoes increases. This report describes a household-based health promotion intervention conducted by students of the Faculty of Medicine, Baiturrahmah University. Community-based educational methods and pre- and post-test evaluations were used to improve public understanding of DHF prevention. The results showed a significant increase in participants’ knowledge scores, from an average of 70.6% to 83.7%. Alternative household-based educational strategies proved effective in increasing community awareness and engagement in mosquito breeding site eradication efforts. This activity also emphasized sustainability through cross-sector collaboration and a community-based approach.
HUBUNGAN ANTARA DIABETES MELITUS TIPE 2 DENGAN KEJADIAN HIPERTENSI DI RUMAH SAKIT ISLAM SITI RAHMAH PADANG Hansah, Rendri Bayu; Fanza Anugrah
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1837

Abstract

Type 2 diabetes mellitus is a metabolic disorder characterized by elevated blood glucose levels due to reduced insulin production by pancreatic beta cells or insulin resistance. One of the main risk factors for type 2 DM is hypertension which is interrelated because high blood pressure can reduce the sensitivity of body cells to insulin. This study aims to determine the relationship between type 2 diabetes mellitus and the incidence of hypertension at Siti Rahmah Islamic Hospital Padang. The type of research is observational with analytic method. Based on the results of data analysis obtained, it can be concluded that this study consisted of 60 samples of type 2 diabetes mellitus patients at Siti Rahmah Islamic Hospital Padang. The approach used was Cross-Sectional. The sample of this study used purposive sampling technique. Based on age characteristics, most were found at the age of 56-65 years with a total of 25 samples (41.7%), the most gender in women with a total of 31 samples (51.7%) and the most occupation in housewives with a total of 18 samples (30%). HbA1c levels in patients with type 2 DM were found to be mostly uncontrolled with 38 samples (63.3%). Hypertension was found to be most prevalent in patients with type 2 DM with 36 samples (60%). The statistical test results obtained a value of p = 0.229 (p>0.05) and r = -0.155 which means that there is no relationship between type 2 diabetes mellitus and the incidence of hypertension in the Siti Rahmah Islamic Hospital in Padang with a very weak correlation and negative correlation direction. Based on data analysis, it is found that there is no relationship between type 2 diabetes mellitus and the incidence of hypertension in Siti Rahmah Islamic Hospital Padang.
DIFFERENCES BETWEEN FOREHEAD AND BACK OF THE HAND TEMPERATURE MEASUREMENTS USING NON-CONTACT INFRARED THERMOMETERS IN HEALTHY YOUNG ADULTS Hansah, Rendri Bayu; Dimas, Gusti Muhammad; Handayani, Kurnia Maidarmi; Sari, Widia; Maribeth, Annisa Lidra; Jaslindo, Lieka Nugrahi
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1848

Abstract

The COVID-19 pandemic necessitated the implementation of rapid, safe, and non-invasive body temperature screening methods to facilitate early identification of potentially infectious individuals. Non-contact infrared thermometers have therefore been widely adopted for this purpose. However, concerns have been raised regarding the accuracy of temperature measurements obtained from different anatomical sites, particularly in the context of increased reliance on alternative measurement locations such as the back of the hand (dorsum manus regio). This study aimed to compare body temperature measurements obtained from the forehead and dorsum manus using a non-contact infrared thermometer, with axillary temperature measured by a digital thermometer as a reference. An analytical observational study with repeated measures was conducted among 70 third-year medical students at Universitas Baiturrahmah. Temperature measurements were performed at the forehead, dorsum manus, and axilla, and participants were divided into control and intervention groups based on environmental measurement conditions. Repeated measures ANOVA revealed significant differences between forehead temperature and both dorsum manus and axillary temperatures, while no significant difference was observed between dorsum manus and axillary measurements. Independent t-tests showed no significant differences between control and intervention groups. These findings suggest that dorsum manus temperature measurements may approximate axillary values under stable conditions in healthy young adults, although caution is required when generalizing to other populations or clinical settings.
Pengaruh Pemberian Vitamin D terhadap Kadar Kreatinin Darah pada Tikus dengan Diabetes Melitus Tipe 2 Prajadina, Inkha; Dhuha, Alief; Sari, Widia; Hansah, Rendri Bayu; Adelin, Prima
Health and Medical Journal Vol. 8 No. 2 (2026): HEME May 2026
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v8i2.2277

Abstract

Latar Belakang : Diabetes melitus tipe 2 adalah kondisi hiperglikemia, dan resistensi insulin, sehingga dapat menyebabkan kerusakan fungsi ginjal. Indikator kerusakan fungsi ginjal adalah peningkatan kreatinin dalam darah.Vitamin D memiliki reseptor pada pankreas dan ginjal. Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh kadar vitamin D terhadap kadar kreatinin darah pada tikus dengan DM tipe 2. Metode: Jenis penelitian ini adalah Experimental In Vivo, dengan rancangan posttest control group design. Penelitian menggunakan 25 ekor tikus putih jantan (Rattus norvegicus) dibagi menjadi 5 kelompok perlakuan yaitu, kelompok A (kontrol), kelompok B (pakan standar + vitamin D 415 IU/hari), kelompok C (DM tanpa vitamin D), kelompok D (DM + vitamin D 415 IU/hari), serta kelompok E (DM + vitamin D 1.100 IU/hari). Data dianalisis menggunakan SPSS. Hasil: Hasil penelitian menunjukkan terdapat perbedaan secara signifikan kadar vitamin D (p=<0,05) yaitu antara kelompok E (DM + vitamin D 1.100 IU) dibandingkan kelompok A (kontrol) (p=0,003). Pada kadar kreatinin didapatkan perbedaan secara signifikan (p=<0,05) pada kelompok B (tidak DM+vitamin D 415 IU) dibandingkan kelompok C (DM tanpa vitamin D) (p=0,007). Tidak terdapat korelasi secara signifikan antara kadar vitamin D terhadap kadar kreatinin darah (p=0,798). Kesimpulan: Terdapat pengaruh pemberian vitamin D terhadap kadar kreatinin. Tidak ada korelasi antara kadar vitamin D terhadap kadar kreatinin.
Co-Authors Adelin, Prima Atika Karina Asmi Dhuha, Alief Dimas, Gusti Muhammad Erdanella Setiawati Fanza Anugrah Gangga Mahatma Ghaniyyatul Khudri Jaslindo, Lieka Nugrahi Kurnia Maidarmi Handayani Maribeth, Annisa Lidra Melya Susanti Muhammad Alfan Syuri Asqa Prajadina, Inkha Relly Angelica Putriz Rosmaini Rosmaini, Rosmaini Sahla Riska Nafiah Sari, Widia Shafira Larissa Suharni Suharni Yanti Fitri Yasa