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All Journal Jurnal Plastik Rekonstruksi JOURNAL LA MEDIHEALTICO Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute
Octovia, Lily Indriani
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Civil Engineering, Building, Construction & Architecture Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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Potential Role of Propolis Flavonoid on Malondialdehyde and Superoxide Dismutase Levels on Endometriosis Mayasari, Citra Krisna; Retno Gunarti, Dwirini; Octovia, Lily Indriani
Journal La Medihealtico Vol. 5 No. 2 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i2.1202

Abstract

Endometriosis is a prevalent gynecological condition that affects around 10% of women within the reproductive age group globally. Recent research indicates that oxidative stress plays a significant role in the development of endometriosis. The present administration of progestin hormone treatment has been shown to induce additional oxidative stress, which is characterized by elevated levels of oxidative stress indicators, including malondialdehyde (MDA), and a reduction in the enzymatic antioxidant superoxide dismutase (SOD). The presence of hormonal imbalances in conjunction with these alterations fosters an environment conducive to the metastasis of endometrial cells. This process initiates inflammatory pathways, angiogenesis, and the formation of lesions and tumors, ultimately exacerbating the state of endometriosis. Research findings indicate that propolis has inherent antioxidant properties, characterized by a high concentration of flavonoid components and phenolic acids. Propolis contains active compounds that have the ability to trap free radicals by forming more stable molecules. Propolis has anti-inflammatory, antimicrobial, and immunomodulatory characteristics, hence potentially enhancing the patient's oxidative stress state, mitigating morbidity, and reducing the duration of hospitalization. This research aims to assess the possible impact of flavonoids found in propolis on the treatment of endometriosis.
Nutrition Therapy in Type 2 Diabetic Burn Patient Ramadhania, Dian Araminta; Wardhana, Aditya; Sinaga, Wina; Wulandari, Yohannessa; Daya, Mulianah; Octovia, Lily Indriani
Jurnal Plastik Rekonstruksi Vol. 8 No. 1 (2021): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14228/jprjournal.v8i1.314

Abstract

Summary: Severe burn patients experience pronounced metabolic changes that caused hyperglycemia. Other existing metabolic conditions such as diabetes mellitus may worsen this condition. Early, adequate, and personalized nutrition therapy may result in better glycemic control and prognosis.A 44-year-old male with severe burn injury involving 27,5% total body surface area (TBSA) and type 2 diabetes mellitus (T2DM) was given early and diabetes-specific nutrition therapy to meet the recommended energy and protein needs. Lower carbohydrate contents and higher mono-unsaturated fatty acids (MUFA) were components of diabetes-specific nutrition therapy. Desirable blood glucose levels, a positive trend of albumin levels, and reduced inflammatory markers were achieved while being given this nutrition therapy. Sepsis was not diagnosed in this patient. The patient was discharged from the hospital after an improvement in clinical condition. Hyperglycemia commonly occurs in critically ill patients, especially with pre-existing T2DM. The provision of prompt and personalized nutrition therapy will improve clinical outcomes.
Dietary Soluble Fiber Improved Fecal Consistency in Burned Patients with Diarrhea Setiawan, Evania; Wardhana, Aditya; Sinaga, Wina; Sari, Ayu Diandra; Satyani, Metta; Octovia, Lily Indriani
Jurnal Plastik Rekonstruksi Vol. 8 No. 2 (2021): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14228/jprjournal.v8i2.330

Abstract

Backgrounds: Diarrhea frequently occurs in severely burned patients attributable to impaired intestinal integrity and dysbiosis. Soluble fiber may improve intestinal barrier function, avoid bacterial translocation, then subsequently prevent and treat diarrhea. Soluble fiber is rapidly fermented by commensal bacteria and produces short-chain fatty acids (SCFA). Case Reports: A 51-year-old male with severe burn injury involving 53,5% total body surface area (TBSA) and diarrhea were given soluble fiber as part of his diet. Results: Administration of 6–10 g/d soluble fiber clinically improves stool consistency, assessed by Bristol Stool Scale, in the severely burned patient. The patient was discharged after 19 days of hospitalization with improvement in clinical condition. Summary: SCFA maintains intestinal integrity, supports the growth of commensal bacteria, and inhibits pathogens. There is no specific recommendation regarding fiber intake in burned patients
Effect of Zinc Supplementation on Fasting Blood Glucose Control in Burn Injury Patients with Type 2 Diabetes Mellitus: a Case Report Tedjaatmadja, Chintya; Rasyid, Nurhayati M; Wulandari, Yohannessa; Octovia, Lily Indriani; Sinaga, Wina; Wardhana, Aditya
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 7 No. - (2023): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v7i-.194

Abstract

Burn injury is the second leading cause of injury in Indonesia. Patients with burn injury may develop zinc deficiency due to loss of exudate and decreased carrier proteins, leading to impaired glucose regulation and inadequate wound healing. Jayawardena et al. showed that zinc supplementation can help regulate blood glucose in patients with diabetes mellitus. This case aims to see the effect of zinc supplementation on fasting blood glucose control in burn injury patients with type 2 diabetes mellitus. A 47-year-old Male with diabetes mellitus and a history of COVID-19 presented with 34% second to third-degree burn injury. The patient was given short-acting insulin 6 IU thrice a day and long-acting insulin 10 IU once a day. Nutrition was increased gradually until it reached 30 kcal/kgBW with protein 1,2 g/kgBW on the 28th day of hospitalization, referring to a diabetes-specific formula, 6x300 kcal. The patient also received zinc sulfate supplementation, 40 mg per day. The patient’s daily zinc intake was 47 mg/dL, and it was analyzed using Nutrisurvey. Fasting blood glucose in the first 28 days was not well-regulated (92-348 mg/dL). After 28 days of zinc supplementation, the patient's fasting blood glucose was stable. (140-180 mg/dL). Uncontrolled blood glucose leads to bacteremia, decreased skin graft takes, and increased mortality. Zinc deficiency can cause greater insulin resistance that can lead to hyperglycemia. Fasting blood glucose was stable after 28 days of zinc supplementation, similar to the previous study. Supplementation can help to regulate fasting blood glucose in burn patients with diabetes mellitus.
Co-Authors Aditya Wardhana Daya, Mulianah Dwirini Retno Gunarti Mayasari, Citra Krisna Ramadhania, Dian Araminta Rasyid, Nurhayati M Sari, Ayu Diandra Satyani, Metta Setiawan, Evania Tedjaatmadja, Chintya Wina Sinaga Wulandari, Yohannessa