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All Journal Jurnal Sehat Indonesia (JUSINDO) Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute
Rasyid, Nurhayati M
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Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Effect of Zinc Supplementation on Fasting Blood Glucose Control in Burn Injury Patients with Type 2 Diabetes Mellitus: a Case Report Tedjaatmadja, Chintya; Rasyid, Nurhayati M; Wulandari, Yohannessa; Octovia, Lily Indriani; Sinaga, Wina; Wardhana, Aditya
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 7 No. - (2023): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v7i-.194

Abstract

Burn injury is the second leading cause of injury in Indonesia. Patients with burn injury may develop zinc deficiency due to loss of exudate and decreased carrier proteins, leading to impaired glucose regulation and inadequate wound healing. Jayawardena et al. showed that zinc supplementation can help regulate blood glucose in patients with diabetes mellitus. This case aims to see the effect of zinc supplementation on fasting blood glucose control in burn injury patients with type 2 diabetes mellitus. A 47-year-old Male with diabetes mellitus and a history of COVID-19 presented with 34% second to third-degree burn injury. The patient was given short-acting insulin 6 IU thrice a day and long-acting insulin 10 IU once a day. Nutrition was increased gradually until it reached 30 kcal/kgBW with protein 1,2 g/kgBW on the 28th day of hospitalization, referring to a diabetes-specific formula, 6x300 kcal. The patient also received zinc sulfate supplementation, 40 mg per day. The patient’s daily zinc intake was 47 mg/dL, and it was analyzed using Nutrisurvey. Fasting blood glucose in the first 28 days was not well-regulated (92-348 mg/dL). After 28 days of zinc supplementation, the patient's fasting blood glucose was stable. (140-180 mg/dL). Uncontrolled blood glucose leads to bacteremia, decreased skin graft takes, and increased mortality. Zinc deficiency can cause greater insulin resistance that can lead to hyperglycemia. Fasting blood glucose was stable after 28 days of zinc supplementation, similar to the previous study. Supplementation can help to regulate fasting blood glucose in burn patients with diabetes mellitus.
The Role of Eicosapentaenoic Acid Supplementation on Muscle Mass in Malnutrition Patients with Squamous Cell Carcinoma of the Tongue: Case Report Kirana, Annisa Nurul; Sunardi, Diana; Manikam, Nurul Ratna Mutu; Rasyid, Nurhayati M
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 7 No. - (2023): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v7i-.195

Abstract

The Indonesian prevalence of lip and oral cavity cancer in 2020 was 14,913, with 5,780 new cases. Head and neck cancer patients are very vulnerable to malnutrition; about 50% are malnourished, and 80% experience unwanted weight loss. Studies showed a significant effect of EPA as an anti-inflammatory substance. A 56-year-old female patient with a diagnosis of tongue squamous cell carcinoma (SCC) presents with the tumor removed along with some teeth. She is experiencing difficulty chewing food and had a weight loss of 8 kg (17%) in the last six months. The patient's muscle mass was 25.5% (low). Patients were given protein intake in the 1.1-1.8 g/kgbw/day range and EPA supplementation of 1.1 g/day. After one month, the BIA measurement showed that her muscle mass had increased to 26.2% and was in the normal category. Omega 3, especially EPA, improved body weight and lean body mass in cancer patients by modulating circulating inflammatory markers, demonstrating an inhibitory effect on inflammatory parameters related to muscle atrophy and lipolysis.Adequate protein intake and supplementation of 1.1 g/day EPA increased muscle mass in malnourished patients and enhanced the effectiveness of cancer therapy.
Evidence-Based Case Report: Efektivitas Jahe Terhadap Kontrol Glikemik dan Profil Lipid pada Pasien Sindrom Metabolik Rasyid, Nurhayati M; Sunardi, Diana
Jurnal Sehat Indonesia (JUSINDO) Vol. 6 No. 01 (2024): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v6i01.82

Abstract

Saat ini, tatalaksana sindrom metabolik (SM) berfokus pada perbaikan parameter metabolik seperti kontrol gula darah dan memperbaiki profil lipid dengan terapi farmakologis. Hal ini menjadi perhatian masyarakat terutama karena penggunaan obat – obatan jangka panjang dan efek samping yang ditimbulkan. Senyawa fitokimia dalam jahe yaitu gingerols dan shogaols memiliki banyak manfaat farmakologis terutama untuk pencegahan dan terapi SM, khususnya penyakit yang ditimbulkan akibat SM seperti diabetes dan penyakit kardiovaskular. Tujuan dari penelitian ini yaitu meneliti apakah jahe dapat memberikan manfaat dalam mengontrol gula darah dan memperbaiki profil lipid pasien SM dibandingkan dengan kondisi tanpa penggunaan jahe. Penelusuran literatur dilakukan di Pubmed®, Cochrane® dan Scopus® pada tanggal 3 Januari 2022 dengan menggunakan advanced search. Dari hasil pencarian melalui 3 database tersebut, dilakukan uji duplikasi dengan menggunakan Covidence. Berdasarkan hasil telaah diatas, efek pemberian suplemen jahe pada pasien sindrom metabolik memberikan hasil yang cukup baik dalam kontrol glikemik dan memperbaiki profil lipid, studi menunjukkan bahwa pemberian suplemen jahe setiap hari dalam waktu lama tidak menyebabkan efek samping yang serius seperti yang sering ditemukan pada pemberian obat oral anti diabetik (OAD) dan obat – obat hiperlipidemia, sehingga pemberian suplemen jahe pada pasien sindrom metabolik aman digunakan jangka panjang dan dapat menjadi pertimbangan.
Co-Authors Aditya Wardhana Diana Sunardi Kirana, Annisa Nurul Nurul Ratna Mutu Manikam Octovia, Lily Indriani Tedjaatmadja, Chintya Wina Sinaga Wulandari, Yohannessa