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Intraoperative Electrically Evoked Auditory Brainstem Response (eABR) examination in cochlear implant candidacy Zizlavsky, Semiramis; Saleh, Rangga Rayendra; Priyono, Harim
Oto Rhino Laryngologica Indonesiana Vol. 54 No. 1 (2024): VOLUME 54, NO. 1 JANUARY - JUNE 2024
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v54i1.664

Background: Cochlear implantation is one of the most promising hearing habilitation methods for patients with profound sensorineural hearing loss (SNHL). One of the difficulties associated with the method is predicting the outcome of the surgery, especially in patients with cochlear nerve abnormalities. Purpose: To evaluate the intraoperative cochlear nerve response using Electrically Evoked Auditory Brainstem Response (eABR), and determine if cochlear implantation was required. Clinical question: How significant was intraoperative eABR in determining the outcome of cochlear implantation? Case report: This study considered two cases with profound bilateral SNHL that underwent intraoperative eABR. The first case involved 10-year-old girl who had used conventional hearing aids for eight years before surgery. She practiced lip reading for communication. The second case involved 4-year-old boy with delayed speech and a history of febrile seizure when he was two years old. He had used a conventional hearing aid for six months. Method: Evidence based literature was conducted through PubMed, Embase, and Wiley. Result: On the first case, eABR examination evoked no response in both ears and the parents decided not to carry on with the surgery. In the second case, eABR examination aroused a significant response in both ears, so the implantation was performed. Three months postoperative, the child was babbling and able to detect sound. Conclusion: eABR could give valuable input in identifying profound bilateral SNHL patients with cochlear nerve abnormality. The high cost of implant devices makes this examination beneficial for the patient’s family in deciding if implantation surgery is required. Keywords: cochlear implant, cochlear nerve hypoplasia, eABR, hearing habilitation, profound sensorineural hearing loss

Association between vitamin D deficiency and otitis media with effusion in children: a systematic review and meta-analysis Restuti, Ratna Dwi; Safitri, Eka Dian; Ranakusuma, Respati Wulansari; Sriyana, Ayu Astria; Priyono, Harim; Saleh, Rangga Rayendra; Marpaung, Dora A; Lazarus, Gilbert
Paediatrica Indonesiana Vol. 64 No. 5 (2024): September 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.5.2024.419-29

Background Vitamin D plays a crucial role in the regulation of inflammation. However, its effect on the development of otitis media effusion (OME), an inflammatory disease of the middle ear without signs of infection, remains largely unknown. Objective To assess the association between vitamin D deficiency and OME in children by systematic review and meta-analysis of the literature. Methods Eligible studies retrieved from PubMed, ProQuest, Embase, Cochrane databases and trial registries published up to 30 October 2022 were included in this review. The risk of bias of the included articles was assessed with the JBI Critical Appraisal Checklist for observational studies. The certainty of evidence was assessed with the Grading of Recommendations Assessment, Development and Evaluation framework. Results We included eight studies (six case-control and two cross-sectional studies) involving 1,114 children, of which four studies were eligible for meta-analysis due to the significant clinical heterogeneity. We found that vitamin D deficiency (defined as vitamin D concentration of 20 ng/mL or less, i.e., ?50 nmol/L) might increase the odds of developing OME by 66.0% (n=514; OR 1.66; 95%CI 1.09 to 2.54; I2=20%), albeit with a very low certainty of evidence. Conclusion There is a very low quality of evidence indicating that vitamin D deficiency is associated with the development of OME in children. Further large, high-quality cohorts and adjusting for confounding factors are warranted to confirm our findings, ideally by exploring the dose-response relationship between vitamin D concentration and the development of OME.

Efektivitas Kamar Ultraviolet Germicidal Irradiation (UVGI) Rumah Sakit Cipto Mangunkusumo untuk Disinfeksi Respirator N95 di Pandemi COVID-19: Studi Pendahuluan Restuti, Ratna Dwi; Priyono, Harim; Saleh, Rangga Rayendra; Sriyana, Ayu Astria; Yusuf, Prasandhya Astagiri; Airlangga, Tri Juda; Prayitno, Ari; Sitohang, Gortap; Arman, Fitri; Priyanto, Suko Dwi
Majalah Kedokteran Indonesia Vol 72 No 1 (2022): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.1-2022-583

Introduction: During the COVID-19 pandemic, where the disease might spread in a medical facility setting, the common problems found in every country is the shortage of personal protective equipment (PPE) for medical personnel – especially the disposable N95 respirators. Thus, a higher amplitude to disinfect and reuse N95 is urgently needed. In this study, we designed an effective and safe disinfection methods through an Ultraviolet Germicidal Irradiation (UVGI) chamber in Dr. Cipto Mangunkusumo Hospital to control the shortage of PPE by disinfecting and reusing disposable N95 respirators. Purpose: To evaluate the dosage and effectiveness of UV-C radiation for disposable N95 respirators disinfection in our designated UVGI chamber. Methods: This study used a cross-sectional design to determine the dose and the effectiveness of UV-C radiation in eradicating SARS-CoV 2 on disposable N95 respirators. Results: Using two different distances from the light source, we confirmed the inverse square law of UV-C radiation power. Irradiation for 2 hours with a radiation dose of 1080 mJ/cm2 resulted in undetected SARS-CoV-2 gene based on PCR examination in 10 out of 10 samples. Conclusion: This UVGI chamber is a potential solution for hospitals or medical facilities to overcome the limitations that occurred in the pandemic by disinfecting PPE.

Intraoperative Electrically Evoked Auditory Brainstem Response (eABR) examination in cochlear implant candidacy Zizlavsky, Semiramis; Saleh, Rangga Rayendra; Priyono, Harim
Oto Rhino Laryngologica Indonesiana Vol. 54 No. 1 (2024): VOLUME 54, NO. 1 JANUARY - JUNE 2024
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v54i1.664

Background: Cochlear implantation is one of the most promising hearing habilitation methods for patients with profound sensorineural hearing loss (SNHL). One of the difficulties associated with the method is predicting the outcome of the surgery, especially in patients with cochlear nerve abnormalities. Purpose: To evaluate the intraoperative cochlear nerve response using Electrically Evoked Auditory Brainstem Response (eABR), and determine if cochlear implantation was required. Clinical question: How significant was intraoperative eABR in determining the outcome of cochlear implantation? Case report: This study considered two cases with profound bilateral SNHL that underwent intraoperative eABR. The first case involved 10-year-old girl who had used conventional hearing aids for eight years before surgery. She practiced lip reading for communication. The second case involved 4-year-old boy with delayed speech and a history of febrile seizure when he was two years old. He had used a conventional hearing aid for six months. Method: Evidence based literature was conducted through PubMed, Embase, and Wiley. Result: On the first case, eABR examination evoked no response in both ears and the parents decided not to carry on with the surgery. In the second case, eABR examination aroused a significant response in both ears, so the implantation was performed. Three months postoperative, the child was babbling and able to detect sound. Conclusion: eABR could give valuable input in identifying profound bilateral SNHL patients with cochlear nerve abnormality. The high cost of implant devices makes this examination beneficial for the patient’s family in deciding if implantation surgery is required. Keywords: cochlear implant, cochlear nerve hypoplasia, eABR, hearing habilitation, profound sensorineural hearing loss

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