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Journal : J-Kesmas: Jurnal Kesehatan Masyarakat (Indonesian Journal of Public Health)

Phytochemical Screening and Blood Glucose Level Effects of Bhee Fruit Extract (Melastoma sp) on Diabetic Mice Rinawati, Rinawati; Muhsin, Sri Wahyuni; Sari, Widia; Hayuningtyas, Afwa; Putri, Suci Eka; Nursia, Lili Eky; Fitri Siregar, Siti Maisyaroh
J-Kesmas: Jurnal Fakultas Kesehatan Masyarakat (The Indonesian Journal of Public Health) Vol 10, No 1 (2023): April 2023
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/j-kesmas.v10i1.7366

Abstract

Diabetes is a non-communicable disease among the highest causes of death worldwide, including in Indonesia. Factors that cause diabetes include pancreatic β-cell damage, genetic factors, and an unhealthy lifestyle. Diabetes is characterized by high blood glucose levels (hyperglycemia) beyond normal limits. Hyperglycaemia can be treated using synthetic chemical drugs or insulin therapy, which has adverse long-term effects. The community believes herbal medicine is an alternative diabetes treatment. Melastoma sp is a plant that has the potential as an antidiabetic agent. This study aimed to determine the effectiveness of ethanol extract of Bhee fruit (Melastoma sp) on blood glucose levels of diabetic mice. This study is a laboratory experiment using laboratory animals. The mice were divided into seven treatment groups with three replicates: KN (normal control), KP (treatment control), KD (diabetes control), KO (drug control), P1 (treatment dose of 100 mg/kgBB extract), P2 (treatment dose of 200 mg/kgBB extract), and P3 (treatment dose of 400 mg/kgBB extract). The study's results, the administration of doses of ethanol extract of the fruit 100, 200, and 300 mg /kgBB for 14 days reduced glucose levels in diabetic mice. However, they could not exceed the ability metformin at a dose of 500 mg/kgBB.
Effect of Germination on Antioxidant Activity of Peanut Sprouts (Arachis Hypogaea) Hayuningtyas, Afwa; Putri, Suci Eka; Rinawati, Rinawati; Khairunnas, Khairunnas; Marniati, Marniati
J-Kesmas: Jurnal Fakultas Kesehatan Masyarakat (The Indonesian Journal of Public Health) Vol 10, No 1 (2023): April 2023
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/j-kesmas.v10i1.7198

Abstract

Peanuts (Arachis hypogaea L.) are plant-based foods that are abundantly available in Indonesia which also have high economic value and are an essential source of protein for many people. In Aceh, peanuts are one of the leading commodities, especially in the districts of Pidie, West Aceh, Aceh Jaya, Nagan Raya, Southwest Aceh and South Aceh. Apart from being rich in protein, it also contains fibre, antioxidants, and other good health components. During germination, proteins, starches, and lipids are metabolised by enzymes. These components are used as building blocks for growth and as a source of energy for respiration. Germination has the advantage of increasing several levels of nutrients, eliminating oligosaccharides that cause flatulence, and increasing several types of vitamins. Previous research reported that soybean germination significantly increased isoflavone levels and antioxidant activity of fresh tempeh flour produced. In this study, the antioxidant activity of peanut sprouts was identified using the DPPH (2,2-diphenyl-1-picryl-hydrazine-hydrate) radical scavenging method in three different germination times. The result shows that the most optimal percentage of antioxidant activity is the 48-hour treatment (88.24%). It also shows that the germination treatment can increase the per cent of antioxidant activity compared to peanuts without germination.