Article Per Year (5 Year)
p-Index From 2021 - 2026
0.659
P-Index
This Author published in this journals
All Journal Riset Informasi Kesehatan Jurnal Medisains Kesehatan
Putra, Fajrian Aulia
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Perbandingan Efektivitas Antidiare Ekstrak Alkhol 96% Daun Jambu Biji (Psidium guajava L) dan Biji Pinang (Areca catechu L) Pada Mencit Dengan Metode Defekasi Ramahyani, Nova; Humaira, Vilma; Putra, Fajrian Aulia
Jurnal Medisains Kesehatan Vol. 4 No. 2 (2023): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v4i2.201

Abstract

Penyakit diare merupakan masalah kesehatan utama di negara berkembang seperti Indonesia, berkontribusi pada tingginya morbilitas dan mortalitas anak-anak. Tradisionalnya, masyarakat menggunakan daun jambu biji dan biji pinang untuk mengatasi gangguan pencernaan, termasuk diare. Penelitian ini bertujuan untuk mengevaluasi efek dan konsentrasi dari ekstrak daun jambu biji dan biji pinang sebagai agen antidiare. Ekstraksi dilakukan dengan metode maserasi menggunakan pelarut alkohol 96%, dan mencit dibagi menjadi empat kelompok. Kelompok kontrol positif dan negatif, serta kelompok ekstrak 350mg/KgBB. Setiap kelompok diinduksi oleum ricini 0,5ml per oral, dengan pengamatan terhadap frekuensi dan lamanya diare selama empat jam. Hasil analisis statistik menunjukkan perbedaan signifikan antara frekuensi diare pada minyak jarak dan biji pinang (sig = 0,000). Frekuensi diare pada minyak jarak lebih rendah daripada daun jambu biji. Perbedaan frekuensi diare antara minyak jarak dan biji pinang juga signifikan (sig = 0,000). Namun, perbedaan frekuensi antara biji pinang dan daun jambu biji tidak terlalu signifikan (sig = 0,443). Kesimpulan penelitian ini adalah bahwa ekstrak etanol daun jambu biji dan biji pinang dosis 350mg/KgBB memiliki aktivitas antidiare yang efektif pada mencit yang diinduksi oleh oleum ricini. Perlu dilakukan uji toksisitas lebih lanjut untuk mengevaluasi keamanannya sebagai agen antidiare.
A Test of the effectiveness of the ethyl acetate fraction of dayak onion bulbs (eleutherine bulbosa (mill.) urb) as an antihypertensive Sari, Putri Nilam; Andika, Miming; Hasnita, Evi; Hasanah, Rizqa; Fitriani, Oriza Sativa; Putra, Fajrian Aulia; Rahmadasmi, Nola; Nanda, Nanda; Handayani, Tuti
Riset Informasi Kesehatan Vol 13 No 1 (2024): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v13i1.836

Abstract

Hypertension is a condition where blood pressure exceeds normal limits, where systolic blood pressure is above 140 mmHg and diastolic blood pressure is above 90 mmHg. One plant that can lower blood pressure is Dayak onion bulbs. The aim of this study was to determine the effectiveness of the ethyl acetate fraction of Dayak onion bulbs (Eleutherine bulbosa (Mill) Urb) in reducing blood pressure in hypertensive male white rats. The method was experimental, using 36 male white rats, divided into 6 groups, namely negative control, positive control, dose group (50, 100, 200 mg/kgbb) and comparison group (catopril). The inducer used was 8% NaCl for 14 days. Blood pressure measurements are carried out using a Non-Invasive Blood Pressure (NIBP) device. Data analysis used One Way Anova and continued with the Duncan test. The results showed that administration of Dayak onion bulb ethyl acetate fraction had an effect on reducing systolic, diastolic, mean arterial blood pressure and heart rate significantly (p<0.05). The conclusion shows that the effective dose in reducing blood pressure is administration of the ethyl acetate fraction at a dose of 200 mg/kgbb. There was a histopathological improvement in the thickness of the left ventricular muscle in mice.
Formulasi Sediaan Obat Kumur (Gargarisma) Kombinasi Ekstrak Daun Jambu Biji dan Biji Pinang Gebbrina, Frank Sisca; Putra, Fajrian Aulia; Syafputri, Try Maya
Jurnal Medisains Kesehatan Vol. 6 No. 1 (2025): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v6i1.521

Abstract

Mouthwash is a liquid dosage form used to prevent and treat oral health problems. However, many commercial mouthwashes contain alcohol, which may cause side effects in certain individuals. This study aimed to formulate and evaluate a mouthwash (gargle) preparation made from a combination of guava leaf extract (Psidium guajava L.) and areca nut seed extract (Areca catechu L.). The extracts were obtained by maceration using 70% ethanol. Three formulations were prepared: F1 containing 3% guava leaf extract and 2.5% areca nut extract, F2 containing 3.5% guava leaf extract and 2.5% areca nut extract, and F3 containing 4% guava leaf extract and 2.5% areca nut extract. Physical evaluations included organoleptic tests, pH, viscosity, clarity, homogeneity, and hedonic (preference) tests. Results showed that all formulations met the required physical quality standards. Based on the preference test, formulation F3 received the highest score (26.2), surpassing F1 and F2. The combination of guava leaf and areca nut extracts shows potential as a natural, effective, safe, and alcohol-free mouthwash formulation.
Co-Authors Evi Hasnita Fitriani, Oriza Sativa Gebbrina, Frank Sisca Miming Andika Nanda Nanda Putri Nilam Sari Rahmadasmi, Nola Ramahyani, Nova Rizqa Hasanah Syafputri, Try Maya Vilma Humaira