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All Journal JOPS (Journal Of Pharmacy and Science) Ensiklopedia of Journal Human Care Journal JPK: Jurnal Proteksi Kesehatan Riset Informasi Kesehatan Journal of Pharmaceutical and Sciences.
Miming Andika
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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UJI AKTIVITAS ANTIOKSIDAN SEDIAAN TEH HERBAL DARI KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUS) DAN KULIT KAYU MANIS (CINNAMOMUM BURMANII) Yulia Yesti; Miming Andika; Harry Ade Saputra; Oryza Sativa Fitriani; Shantrya Dhelly Susanti; Fahira Azlaini Burma
Ensiklopedia of Journal Vol 5, No 2 (2023): Volume 5 No. 2 Edisi 1 Januari 2023
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (320.824 KB) | DOI: 10.33559/eoj.v5i2.1399

Abstract

Indonesia is a plant-producing country, especially in the tropics of Indonesia there are 30,000 plant species. Of these, there are 9,600 plant species that are useful as medicine, but 200 species have been used as raw materials for the herbal industry for health, one of which is from red dragon fruit skin (Hylocereus polyrhizus). This type of research is experimental research. This research was conducted qualitatively and quantitatively which was carried out from July-August 2022. The data obtained in this study were used to determine the antioxidant content of herbal tea preparations in red dragon fruit skin (Hylocereus polyrhizus) and cinnamon bark (Cinnamomum burmani) and for data analysis, the data obtained was tested linear regression using the SPSS v16 program. to obtain a linear equation, so that the value of antioxidant activity (IC50) is obtained. Data analysis was continued with the one way ANOVA method (ANOVA). So it can be concluded that the herbal tea preparations of red dragon fruit skin (Hylocereus polyrhizus) and cinnamon bark (Cinnamomum burmanii) in the antioxidant test had a good temperature at 80OC (45.123 ppm) because based on IC50 because the lower the IC50 value, the stronger the IC50 value. The IC50 value is the effective concentration of an antioxidant substance capable of inhibiting the activity of a free radical by 50%. For the IC50 value for the combination tea of red dragon fruit skin and cinnamon bark at 60OC (47.605 ppm) and 100OC (48.585 ppm). Where free radicals are very good at heating temperatures of 80OC. The results showed that the heating temperature of herbal tea simplicia had an effect on the antioxidants produced in each sample. It can be concluded that from the 3 differences in heating temperature variations, the antioxidant yield was very good at 80OC with an IC50 result of 45.123 ppm. Further research needs to be done with the manufacture of dragon fruit peel and cinnamon bark herbal tea in the form of dyes so that the presentation is faster, easier and more practical. Further research is needed to determine the shelf life of dragon fruit peel and cinnamon herbal tea products.Keywords: Red Dragon Fruit Peel, Cinnamon Bark Herbal Tea Preparation.
Preparation And Evaluation Of Hydrogel From Super Red Dragon Fruit Skin Extract (Selenicereus costaricensis) Setiawan, Dwi; Yesti, Yulia; Rahmadasmi, Nola; Fitriani, Oryza Sativa; Andika, Miming; Hasanah, Rizqa; .AH, Ahdi Dinil Haq; Wulandari, Desti; Putri, Nurdina
JURNAL PROTEKSI KESEHATAN Vol 13 No 2 (2024): JPK: Jurnal Proteksi Kesehatan
Publisher : Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v13i2.947

Abstract

Dragon skin is a waste that is rarely used and often discarded. The dragonfruit skin has antioxidant activity related to the anthocyanin content that protects the skin from oxidation damage to prevent premature aging. This study introduces a new approach to utilizing super red dragon fruit skin waste often thrown away, by formulating it into a hydrogel preparation with potential as a cosmetic product. An experimentally used method with a true-experimental design. There are 7 formulas, F1 (base), F2, F3, and F4 (with ultrasonic extract 1%, 2%, 3.). The evaluations included organoleptic tests, homogeneity tests, viscosity testing, pH tests, swelling ratio, freeze and thaw. The results of this study show that super red dragonfruit leather extracts can be formed in hydrogel preparations and have good physical quality properties.
ANALYSIS OF DEXAMETASONE LEVELS IN HERBAL WEIGHT GAIN MEDICINE CIRCULATING IN BUKITTINGGI CITY USING UV-VIS SPECTROPHOTOMETRY Fitriani, Oryza Sativa; Khaidir, Muhammad; Hasanah, Rizqa; Rahmadasmi, Nola; Andika, Miming
HUMAN CARE JOURNAL Vol 10, No 1 (2025): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v10i1.3333

Abstract

Chemical drugs are chemical substances added to traditional medicines or herbal medicines to strengthen the indications. One of the chemical drugs that is often added to herbal medicines is dexamethasone. With the presence of dexamethasone content that is intentionally added to herbal medicines, it can increase the weight of consumers who consume the herbal medicine. Dexamethasone in long-term use can cause unwanted hormonal effects, namely a series of changes called iatrogenic Cushing's Syndrome (moon face) and osteoporosis. This study aims to identify the chemical drug dexamethasone in weight-gaining herbal medicines sold in the city of Bukittinggi using purposive sampling techniques and analyzing its levels. The research method was carried out using UV-Vis spectrophotometry. The results of the study showed that there were 2 samples of herbal weight gain medicines that positively contained dexamethasone with a concentration of 1.9771% in herbal medicine 2 and 0.2092% in herbal medicine 7. In conclusion, out of 10 herbal weight gain medicines sold in Bukittinggi City, there were 2 herbal medicine samples that contained the chemical drug dexamethasone.
Pembuatan dan Evaluasi Sediaan Masker Gel Peel Off dari Ekstrak Air Mikroalga Spirulina Platensis Kirani , Zabilla; Putra , Billy Harnaldo; Rahmadasmi, Nola; Fitriani , Oryza Sativa; Nanda , Nanda; Andika, Miming; Hasanah , Rizqa; Haq. AH, Ahdi Dinil; Wulandari , Desti
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.620

Abstract

Background: The microalgae Spirulina platensis is a microalgae with numerous benefits, particularly in the fields of health and cosmetics. One of its active compounds, phycocyanin, is a water-soluble antioxidant that is beneficial for facial skincare. A peel-off gel mask is a practical cosmetic product that can be peeled off directly after drying. Objective: This study aimed to develop a peel-off gel mask containing Spirulina platensis water extract and evaluate its physical quality. Methods: The peel-off gel mask was prepared by adding Spirulina platensis water extract at three different concentrations: 0.25% (F1), 0.5% (F2), and 0.75% (F3). Physical quality evaluation included organoleptic testing, homogeneity, viscosity, pH, drying time, adhesiveness, and stability at 4°C and 40°C. A comparison was also made with a commercial spirulina mask product (F4, 0.25%). Results: The physical quality assessment showed that all formulations met the requirements for organoleptic properties, homogeneity, viscosity, pH, drying time, and adhesiveness. In the stability test, the base formula (F0) and F1 (0.25%) were the most stable in terms of organoleptic parameters, while all formulations remained stable in pH. The viscosity of all four formulations remained stable after two months of storage. The commercial mask (F4) exhibited similar physical quality results to F1, with both meeting all requirements. Conclusion: The peel-off gel mask containing Spirulina platensis water extract was successfully developed with satisfactory physical quality. The 0.25% concentration formula (F1) demonstrated good stability, comparable to commercially available products.
A Test of the effectiveness of the ethyl acetate fraction of dayak onion bulbs (eleutherine bulbosa (mill.) urb) as an antihypertensive Sari, Putri Nilam; Andika, Miming; Hasnita, Evi; Hasanah, Rizqa; Fitriani, Oriza Sativa; Putra, Fajrian Aulia; Rahmadasmi, Nola; Nanda, Nanda; Handayani, Tuti
Riset Informasi Kesehatan Vol 13 No 1 (2024): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v13i1.836

Abstract

Hypertension is a condition where blood pressure exceeds normal limits, where systolic blood pressure is above 140 mmHg and diastolic blood pressure is above 90 mmHg. One plant that can lower blood pressure is Dayak onion bulbs. The aim of this study was to determine the effectiveness of the ethyl acetate fraction of Dayak onion bulbs (Eleutherine bulbosa (Mill) Urb) in reducing blood pressure in hypertensive male white rats. The method was experimental, using 36 male white rats, divided into 6 groups, namely negative control, positive control, dose group (50, 100, 200 mg/kgbb) and comparison group (catopril). The inducer used was 8% NaCl for 14 days. Blood pressure measurements are carried out using a Non-Invasive Blood Pressure (NIBP) device. Data analysis used One Way Anova and continued with the Duncan test. The results showed that administration of Dayak onion bulb ethyl acetate fraction had an effect on reducing systolic, diastolic, mean arterial blood pressure and heart rate significantly (p<0.05). The conclusion shows that the effective dose in reducing blood pressure is administration of the ethyl acetate fraction at a dose of 200 mg/kgbb. There was a histopathological improvement in the thickness of the left ventricular muscle in mice.
Uji Efektivitas Ekstrak Dan Fraksi Daun Matoa Terhadap Antihipertensi Dan Antihiperkolesterolemia Secara In Vivo Miming Andika; Tita Adhaha Febriana; Latyfa’ Aini; Nanda Nanda; Fajrian Aulia Putra; Oryza Sativa Fitriani
JURNAL FARMASI DAN MAKANAN Vol 7 No 1 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i1.4101

Abstract

Hiperkolesterolemia dan hipertensi merupakan penyakit kardiovaskular yang berbahaya. Beberapa faktor resiko bersifat permanen seperti usia, jenis kelamin, genetik dan faktor lainnya dapat dimodifikasi seperti merokok, kurangnya aktivitas fisik, gizi buruk, tekanan darah tinggi, diabetes tipe II, dislipidemia dan obesitas. Aterosklerosis dan hipertensi berpotensi berkembang menjadi penyakit kardiovaskular yang berbahaya seperti infark miokard dan stroke. Bahan alam banyak digunakan sebagai alternatif pengobatan kardiovaskular seperti daun matoa, daun matoa banyak digunakan sebagai oabat diabetes melitus, diare dan disentri. Tujuan penelitian ini adalah untuk melihat efektivitas dan pengaruh lama pemberian ekstrak dan fraksi daun matoa Pometia pinnata J. R Forst & G. Forst terhadap penurunan kolesterolemia dan hipertensi pada hewan uji. Pada penelitian ini menggunakan hewan uji berupa tikus dan burung puyuh. Pengukuran tekanan darah menggunakan instrumen CODA®, dan pengukuran kadar kolesterol meggunakan fotometer klinik. Hasil dari penelitian ini menunjukkan bahwa pemberian ekstrak daun matoa dapat mempengaruhi kadar kolesterolemia dengan dosis yang efektif 300 mg/kgbb, dan fraksi daun matoa mempengaruhi tekanan darah dengan dosis efektif Kesimpulan dari penelitian ini menyatakan ekstrak dan fraksi daun matoa dapat menurunkan kadar kolesterol dalam darah dan tekanan darah pada hewan percobaan serta semakin tinggi dosis yang diberikan maka semakin tinggi juga penurunannya.
Co-Authors .AH, Ahdi Dinil Haq Billy Harnaldo Putra, Dini Fatmi, Dwi Setiawan Evi Hasnita Fahira Azlaini Burma Fajrian Aulia Putra Fitriani , Oryza Sativa Fitriani, Oriza Sativa Fitriani, Oryza Sativa Haq. AH, Ahdi Dinil Harry Ade Saputra Khaidir, Muhammad Kirani , Zabilla Latyfa’ Aini Nanda , Nanda Nanda Nanda Nanda Nanda Nurdina Putri Oryza Sativa Fitriani Oryza Sativa Fitriani Putra, Fajrian Aulia Putri Nilam Sari Rahmadasmi, Nola Rizqa Hasanah Shantrya Dhelly Susanty Tita Adhaha Febriana Vilma Humaira Wulandari , Desti Wulandari, Desti Yulia Yesti Yulia Yesti, Yulia