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All Journal JOPS (Journal Of Pharmacy and Science) Human Care Journal JPK: Jurnal Proteksi Kesehatan Riset Informasi Kesehatan Journal of Pharmaceutical and Sciences.
Rizqa Hasanah
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Preparation And Evaluation Of Hydrogel From Super Red Dragon Fruit Skin Extract (Selenicereus costaricensis) Setiawan, Dwi; Yesti, Yulia; Rahmadasmi, Nola; Fitriani, Oryza Sativa; Andika, Miming; Hasanah, Rizqa; .AH, Ahdi Dinil Haq; Wulandari, Desti; Putri, Nurdina
JURNAL PROTEKSI KESEHATAN Vol 13 No 2 (2024): JPK: Jurnal Proteksi Kesehatan
Publisher : Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v13i2.947

Abstract

Dragon skin is a waste that is rarely used and often discarded. The dragonfruit skin has antioxidant activity related to the anthocyanin content that protects the skin from oxidation damage to prevent premature aging. This study introduces a new approach to utilizing super red dragon fruit skin waste often thrown away, by formulating it into a hydrogel preparation with potential as a cosmetic product. An experimentally used method with a true-experimental design. There are 7 formulas, F1 (base), F2, F3, and F4 (with ultrasonic extract 1%, 2%, 3.). The evaluations included organoleptic tests, homogeneity tests, viscosity testing, pH tests, swelling ratio, freeze and thaw. The results of this study show that super red dragonfruit leather extracts can be formed in hydrogel preparations and have good physical quality properties.
ANALYSIS OF DEXAMETASONE LEVELS IN HERBAL WEIGHT GAIN MEDICINE CIRCULATING IN BUKITTINGGI CITY USING UV-VIS SPECTROPHOTOMETRY Fitriani, Oryza Sativa; Khaidir, Muhammad; Hasanah, Rizqa; Rahmadasmi, Nola; Andika, Miming
HUMAN CARE JOURNAL Vol 10, No 1 (2025): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v10i1.3333

Abstract

Chemical drugs are chemical substances added to traditional medicines or herbal medicines to strengthen the indications. One of the chemical drugs that is often added to herbal medicines is dexamethasone. With the presence of dexamethasone content that is intentionally added to herbal medicines, it can increase the weight of consumers who consume the herbal medicine. Dexamethasone in long-term use can cause unwanted hormonal effects, namely a series of changes called iatrogenic Cushing's Syndrome (moon face) and osteoporosis. This study aims to identify the chemical drug dexamethasone in weight-gaining herbal medicines sold in the city of Bukittinggi using purposive sampling techniques and analyzing its levels. The research method was carried out using UV-Vis spectrophotometry. The results of the study showed that there were 2 samples of herbal weight gain medicines that positively contained dexamethasone with a concentration of 1.9771% in herbal medicine 2 and 0.2092% in herbal medicine 7. In conclusion, out of 10 herbal weight gain medicines sold in Bukittinggi City, there were 2 herbal medicine samples that contained the chemical drug dexamethasone.
Pembuatan dan Evaluasi Sediaan Masker Gel Peel Off dari Ekstrak Air Mikroalga Spirulina Platensis Kirani , Zabilla; Putra , Billy Harnaldo; Rahmadasmi, Nola; Fitriani , Oryza Sativa; Nanda , Nanda; Andika, Miming; Hasanah , Rizqa; Haq. AH, Ahdi Dinil; Wulandari , Desti
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.620

Abstract

Background: The microalgae Spirulina platensis is a microalgae with numerous benefits, particularly in the fields of health and cosmetics. One of its active compounds, phycocyanin, is a water-soluble antioxidant that is beneficial for facial skincare. A peel-off gel mask is a practical cosmetic product that can be peeled off directly after drying. Objective: This study aimed to develop a peel-off gel mask containing Spirulina platensis water extract and evaluate its physical quality. Methods: The peel-off gel mask was prepared by adding Spirulina platensis water extract at three different concentrations: 0.25% (F1), 0.5% (F2), and 0.75% (F3). Physical quality evaluation included organoleptic testing, homogeneity, viscosity, pH, drying time, adhesiveness, and stability at 4°C and 40°C. A comparison was also made with a commercial spirulina mask product (F4, 0.25%). Results: The physical quality assessment showed that all formulations met the requirements for organoleptic properties, homogeneity, viscosity, pH, drying time, and adhesiveness. In the stability test, the base formula (F0) and F1 (0.25%) were the most stable in terms of organoleptic parameters, while all formulations remained stable in pH. The viscosity of all four formulations remained stable after two months of storage. The commercial mask (F4) exhibited similar physical quality results to F1, with both meeting all requirements. Conclusion: The peel-off gel mask containing Spirulina platensis water extract was successfully developed with satisfactory physical quality. The 0.25% concentration formula (F1) demonstrated good stability, comparable to commercially available products.
A Test of the effectiveness of the ethyl acetate fraction of dayak onion bulbs (eleutherine bulbosa (mill.) urb) as an antihypertensive Sari, Putri Nilam; Andika, Miming; Hasnita, Evi; Hasanah, Rizqa; Fitriani, Oriza Sativa; Putra, Fajrian Aulia; Rahmadasmi, Nola; Nanda, Nanda; Handayani, Tuti
Riset Informasi Kesehatan Vol 13 No 1 (2024): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v13i1.836

Abstract

Hypertension is a condition where blood pressure exceeds normal limits, where systolic blood pressure is above 140 mmHg and diastolic blood pressure is above 90 mmHg. One plant that can lower blood pressure is Dayak onion bulbs. The aim of this study was to determine the effectiveness of the ethyl acetate fraction of Dayak onion bulbs (Eleutherine bulbosa (Mill) Urb) in reducing blood pressure in hypertensive male white rats. The method was experimental, using 36 male white rats, divided into 6 groups, namely negative control, positive control, dose group (50, 100, 200 mg/kgbb) and comparison group (catopril). The inducer used was 8% NaCl for 14 days. Blood pressure measurements are carried out using a Non-Invasive Blood Pressure (NIBP) device. Data analysis used One Way Anova and continued with the Duncan test. The results showed that administration of Dayak onion bulb ethyl acetate fraction had an effect on reducing systolic, diastolic, mean arterial blood pressure and heart rate significantly (p<0.05). The conclusion shows that the effective dose in reducing blood pressure is administration of the ethyl acetate fraction at a dose of 200 mg/kgbb. There was a histopathological improvement in the thickness of the left ventricular muscle in mice.
Potensi Ekstrak Etanol Daun Pepaya Emas (Carica Papaya L) Sebagai Antihipertensi dan Nefroprotektif: In Vivo Miming Andika; Thesa Fitri Yatiningsih; Yuliarti; Rizqa Hasanah
JURNAL FARMASI DAN MAKANAN Vol 9 No 1 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i1.6932

Abstract

Hypertension is a condition in which the systolic blood pressure is above 140 mmHg and the diastolic blood pressure is above 90 mmHg. Kidney failure is a progressive, irreversible disorder of renal function, in which kidney function declines in maintaining metabolism, fluid, and electrolyte balance, resulting in uremia. The purpose of this study was to determine the effectiveness of ethanol extract of papaya leaves (Carica papaya L) in reducing blood pressure and serum creatinine levels in male white rats. This study was experimental in nature, using 60 rats divided into 12 groups, namely negative control, positive control, comparison group (captopril), and dose groups (100, 200, 400 mg/kg body weight). The inducer used for hypertension was 8% NaCl and the inducer for kidney failure was CCl4. Blood pressure measurements were carried out using a Non-Invasive Blood Pressure (NIBP) device, and the measurement of serum creatinine levels was performed using a photometer. Data analysis was conducted using One Way ANOVA followed by Duncan's test. The results showed that the administration of papaya leaf ethanol extract significantly affected the reduction of blood pressure and serum creatinine levels (p<0.05). It can be concluded that the most effective dose for lowering blood pressure is 400 mg/kg body weight, and the most effective dose for reducing serum creatinine levels is 100 mg/kg body weight.
Co-Authors .AH, Ahdi Dinil Haq Billy Harnaldo Putra, Dini Fatmi, Dwi Setiawan Evi Hasnita Fitriani , Oryza Sativa Fitriani, Oriza Sativa Fitriani, Oryza Sativa Haq. AH, Ahdi Dinil Khaidir, Muhammad Kirani , Zabilla Miming Andika Miming Andika Nanda , Nanda Nanda Nanda Nurdina Putri Putra, Fajrian Aulia Putri Nilam Sari Rahmadasmi, Nola Thesa Fitri Yatiningsih Wulandari , Desti Wulandari, Desti Yulia Yesti, Yulia Yuliarti