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Teratogenic Effects of Arabica Coffee (Coffea arabica L) on Rats During the Organogenesis Period Reza Destri Anggi; Yuandani; Dalimunthe, Aminah
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 3 No. 2 (2020): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v3i2.4311

Abstract

The purpose of the research was to evaluate the teratogenic effect caused by theprovision of Arabica coffee solution with variations of 0.36 ml, 0.72 ml and 1.08 ml withpositive control of caffeine at a dose of 300 mg / kg bw to rats during organogenesis. Themeasurement parameters in this study are the appearance of reproduction, externalmalformations and scalal malformations. The results in this study found that theadministration of Arabica coffee solution with a volume of 1.08 ml and caffeine 300 mg /kg bb caused an abnormality in the reproductive appearance of weight loss and body length,whereas for extrenal malformation and scalal malforation no abnormalities were found ineach administration of the solution Arabica coffee and caffeine.  
SOSIALISASI NANOEMULGEL ANTIBAKTERI KOMBINASI EKSTRAK TEMULAWAK DAN TEMUPUTIH UNTUK MENGATASI INFEKSI MRSA DI DESA PAYAMABAR Diding Pradita; Reza Destri Anggi; Azzura Ligo; Puspita Kusuma Wardani, Dea; Aminah, Nurul
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 5 No. 2 (2025): Desember 2025
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v5i2.285

Abstract

Infections caused by Methicillin-Resistant Staphylococcus aureus (MRSA) remain a major health concern due to their resistance to commonly used antibiotics, driving interest in safe and effective natural-based alternatives. This community service program introduced an antibacterial nanoemulgel formulated from combined extracts of Curcuma xanthorrhiza (temulawak) and Curcuma zedoaria (temu putih) to residents of Paya Mabar Village, Stabat District, Langkat Regency.  The activities included interactive education on the dangers of bacterial resistance, a demonstration of nanoemulgel preparation, and small group discussions to explore participants’ understanding of modern herbal-based treatments. Community members showed strong enthusiasm, reflected in active participation and improved awareness of antibiotic resistance and the potential of local medicinal plants. The outcomes indicated that a combined educational and hands-on approach effectively enhanced public knowledge of infection prevention and encouraged appreciation for natural ingredients as innovative health solutions. The community recognized nanoemulgel as a bridge between traditional wisdom and modern pharmaceutical technology.