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The Influences of Tutorial Discussion on Achievement of The Learning Objectives Immunology Block at Faculty of Medicine Sebelas Maret University Abdullah Al-Hazmy; Ratna Kusumawati; Lukman Aryoseto
Nexus Pendidikan Kedokteran dan Kesehatan Vol 4, No 1 (2015): Nexus Pendidikan Kedokteran & Kesehatan
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Tutorial discussion is one method of Problem Based Learning (PBL), this method divided students into small groups and then given a mdical case as a trigger to search further information, and they discuss knowledge and information that accompanied by a tutor. The success of the tutorial discussion process may affect the achievement of learning objectives block. The aim of the research is to determine differences in the achievement of learning objectives Immunology block scenarios before and after tutorial discussion. Methods: This research was a longitudinal observational analytic. The data were collected by using simple random sampling with 47 sampels of students batch 2013 and had been assessed at Medical Faculty of Sebelas Maret University. The learning objectives of this comparation study measured by pretest and posttest questions that have been tested validation by experts. The study was conducted using quantitative method and the results were analyzed by using Paired t-test. Results: The average value of pretest-posttest before and after tutorial discussion is 28.51-60.85 for the first scenario, 22.34-62.55 for the second scenario, and 16.81-65.32 for the third scenario. Paired t-test results showed significant differences with p <0.05 (p=0.000) for the value of pretest-posttest three scenarios. Conclusions: The achievement of learning objectives scenario in immunology block before and after tutorial discussion is significant. Keywords: tutorial discussion, learning objectives, Immunology block
The Improvement of Learning Competency of Skills Lab of Electrocardiography through Academic Motivation and Self-Directed Learning Readiness among Medical Student Sotya Satmaka Adira; Ratna Kusumawati; Eti Poncorini
Nexus Pendidikan Kedokteran dan Kesehatan Vol 6, No 1 (2017): Nexus Pendidikan Kedokteran & Kesehatan
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Introduction: Academic motivation is the key to generate students readiness to study by their own will, as it calls Self Directed Learning Readiness (SDLR). SDLR can increase students learning input, especially in this case which is the learning process of Skills Lab of Electrocardiography, which has complex learning subject and high number of failed student. This research purpose is to find the correlation of academic motivation with self directed learning readiness. Methods: This research was a cross-sectional observational analytic. Research location was in Faculty of Medicine of Sebelas Maret University. The subjects were medical students of Sebelas Maret University class of 2012, 2013, and 2014 generation. The subjects selected by using proportional stratified random sampling method. Academic motivation was measured by Motivated Strategies for Learning Questionnaire (MSLQ) . SDLR was measured by questionnaire of Self Directed Learning Readiness for Nurse Education (SDLR-NE). The statistical analysis of obtained research data was Pearson Correlation Test. Results: Normality test showed that data of academic motivation and self directed learning readiness was normally distributed. Pearson correlation test result was 0.551 with p = 0.000 Conclusions: This research has showed the correlation between academic motivation and SDLR. Higher of academic motivation value then the SDLR in learning process of Skills Lab of Elctrocardiography value will also be higher. Keywords: Motivation, Academic Motivation, Self Directed Learning Readiness
Qualitative Study the Correlation between Intensity of Reciting the Quran with Students Anxiety in facing Objective Structured Clinical Examination (OSCE) on Medical Licensing Examination Uji Kompetensi Mahasiswa Program Profesi Dokter (UKMPPD) Syayma Karimah; Ratna Kusumawati; Bulan Kakanita Hermasari
Nexus Pendidikan Kedokteran dan Kesehatan Vol 5, No 2 (2016): Nexus Pendidikan Kedokteran & Kesehatan
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Introduction: Objective Sturctured Clinical Examination (OSCE) on medical licensing examination Uji Kompetensi Mahasiswa Program Profesi Dokter (UKMPPD) that determines students to become a medical doctor is high potentially causing anxiety. There are some methods to overcome someone anxiety, one of them is by doing spiritual activity like reciting the Quran. The purpose of this study was to explore the correlation between intensity of reciting the Quran with students anxiety in facing OSCE on medical licensing examination. Methods: The research design was a qualitative study with phenomenology approach.The sampling technique was purposive sampling method. The sample was medical students of Faculty of Medicine University of Sebelas Maret Surakarta those were participating OSCE medical licensing examination on November 2015. The informations obtained by focus group interview to eight students. Analysis of the data in this study was done by content analysis method. Results: This study showed the reasons of students anxiety, manifestations of students anxiety, and the methods those were used by sudents to decrese their anxiety in facing OSCE medical licensing examination. The correlation between doing spiritual activities especially intensity of reciting the Quran with students anxiety in facing examinations also found in this study. Conclusion: This study concludes doing spiritual activities especially reciting the Quran decreases students anxiety in facing examination. Keywords: anxiety, intensity of reciting the Quran, Obejective Structured Clinical Examination, medical licensing examination, Uji Kompetensi Mahasiswa Program Profesi Dokter (UKMPPD)
Relation Between Hypertension and Cognitive Impairment in Elderly at Posyandu Lansia Developed by Puskesmas Ngoresan, Surakarta Matius Dimas Reza Dana Ismaya; Ratna Kusumawati; Bhisma Murti
Nexus Kedokteran Komunitas Vol 6, No 2 (2017): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Introduction: Hypertension is a condition of increasing blood pressure and it causes certain symptoms which will further damage the body. Elderly or a person older than 60 years old will be more susceptible to hypertension because there were many changes in body function and structure. Hypertension will lead to changes in vascular structures, disruption of cerebral autoregulation, white matter lesion, lacunar infarction, and eventually result in cognitive impairment. This study aims to determine a relation of hypertension to cognitive impairment in elderly at Posyandu Lansia developed by Puskesmas Ngoresan, Surakarta and factors which affect cognitive impairment. Methods: This was an observational analytic research with a cross sectional study. This research was done in Posyandu Lansia and general clinic of Puskesmas Ngoresan, Surakarta. The subject of the research was the elderly with hypertension at Puskesmas Ngoresan, Surakarta, male, aged ? 60 years, and literate. The 60 samples were taken using purposive sampling technique, which consist of 30 with hypertension and 30 without hypertension. Blood pressure was measured by using mercury sphygmomanometer. The assesment of cognitive function was done by using the Indonesian version of Montreal Cognitive Assessment (MoCA-Ina). The data were analyzed using chi square and multiple logistic regression. Results: The result of analytic test between hypertension and cognitive impairment showed significant relation (OR = 7.59; CI 95% = 1.73 33.30; p = 0,007). There was significant relation between smoking activity and cognitive impairment (OR = 0.07; CI 95% = 0.01 0.40; p = 0.003). Level of education and hypertension duration showed non significant relation to cognitive impairment with each value is p = 0.059; p = 0.697. Conclusions: Hypertension is a factor that increases the risk of cognitive impairment and smoking is a factor that decreases the risk of cognitive impairment. Keywords: Cognitive Impairment, Hypertension
The Impact of Railway Noise Upon the Quality of Life Michael Sophian Putra; Ratna Kusumawati; R. Prihandjojo Andri Putranto
Nexus Kedokteran Komunitas Vol 6, No 1 (2017): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Introduction: Railway noise is an unexpected noise caused by either the machine of the trains or the friction between the wheels and the railroads. Long lasting noise has a negative impact upon psychological condition, mental function, and the quality of ones life. The aim of this study was to know whether there was an impact of the railway noise upon the quality of life of the society living at the banks of railroads in Nusukan, Surakarta. Methods: This was an observational analytic research with a cross sectional study. This research was done in Nusukan neighborhood, Banjarsari subregency, Surakarta town, from October to November 2015. The subject of the research was the society living at the banks of the railroads in Nusukan for the minimum of 1 year, men, and between 20-59 years of age. The sample taking was done by using purposive sampling technique as many as 60 people consisting of 30 respondents exposed by the railway noise of > 55dB and 30 respondents exposed by the railway noise of ? 55dB. The measurement of the noise was done by using a sound level meter device. The measurement upon the quality of life was made by using questionnaire of Nottingham Health Profile (NHP). The data were analyzed with unpaired t test (? = 0.05). Result: The result of the unpaired t test showed the average score of the quality of life of the respondents exposed by the railway noise of > 55dB was significant lower than that of the respondents exposed by the railway noise of ? 55dB, with p = 0.000 (P < 0.05). Conclusion: Respondents exposed by the railway noise of less than or as much as the threshold value (? 55dB) had better average quality of life than the respondent exposed by the railway noise which was higher than the threshold value (> 55dB). Keywords: Quality of life, railway noise, Nottingham Health Profile (NHP)
The association between body mass index (BMI) and neck circumference with sleep quality Wuryan Dewi Miftahtyas Arum; Budiyanti Wiboworini; Ratna Kusumawati
Nexus Kedokteran Komunitas Vol 3, No 2 (2014): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Backgrounds: Sleep disorders can affect on decreased concentration and academic achievement, sleepy while driving, risk behavior, depression, social interaction disorder, and bad health. Obesity is closely related to sleep-related breathing disorder that can affect on declining sleep quality as well. Body mass index (BMI) and neck circumference are simple screening to determine obesity. This research aims to know the association between BMI and neck circumference with sleep quality. Methods: This was an analytic observational research with cross sectional design in Buran Village, Tasikmadu, Karanganyar. Fifty six subjects 22-50 years of age were selected by using accidental sampling. BMI and neck circumference were obtained by anthropometric measurement. Sleep quality was obtained by PSQI questionnaire. Data were statistically analyzed using Spearman test and Mann-Whitney test. Results: The Spearman analysis indicated that there was no significant association between BMI and sleep quality (p = 0.070) as well as neck circumference and the sleep quality (p = 0.781). Mann Whitney analysis indicated that there was a significant association between psychological condition and sleep quality (p < 0.001). Conclusions: There are no significant associations between BMI and sleep quality as well as neck circumference and sleep quality. Psychological condition has significant correlation with sleep quality. Keywords: BMI, neck circumference, sleep quality
The Association between Exercise Activity and Postural Orthostatic Tachycardia Syndrome (POTS) in Female College Students Afifah Novita Yuliastuti; . Balgis; Ratna Kusumawati
Nexus Biomedika Vol 4, No 3 (2015): Nexus Biomedika
Publisher : Nexus Biomedika

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Abstract

Background: Postural Orthostatic Tachycardia Syndrome (POTS) is illness manifestations caused by autonomic dysfunction. Subjects with POTS predominantly are young women between 20-40 year old and most of them are college student. Exercise has proven can improve the function of body systems. College studentss time is mostly for academic activity and not much time for exercise. The main aim of this research was to know the association between exercise activity and the incidence of POTS in female college students. Method: This research was an analytical observational using case-control design approach. Samples were fifty eight female college students with POTS (16-23 years old) selected using purposive sampling. This study was done from November to December 2014 at Medical School of Sebelas Maret University Surakarta. Data of Exercise activity were obtained by questionnaire. Diagnosis of POTS was conducted by measuring heart rate using pulsemeter on Active Stand Test (AST) position while orthostatic symptoms were gotten by interview. Data were analyzed using Chi-Square test. Result: This study showed that most of the subjects with POTS (27.6%) had lower exercise activity than those without POTS (37.9%). The result of Chi Square analysis was p = 0.007. Conclusion: There was significant association between exercise activity and the incidence of POTS in female college students. Keywords: exercise activity, heart rate, POTS
Molecular Docking Analysis of Family Fabaceae Phytochemistry to Estrogen Receptor Alpha Compared to Tamoxifen in Breast Cancer Ega Caesaria Pratama Putra; Riza Novierta Pesik; Ratna Kusumawati
Nexus Kedokteran Translasional Vol 4, No 1 (2015): Nexus Kedokteran Translasional
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Breast cancer is the second most common cancer.Estrogen is the risk factor of breast cancer. Estrogen receptor ? is expressed by 50-80% of breast cancer. The mechanism of estrogen is mediated by estrogen receptor ? and estrogen receptor ?. Tamoxifen is a selective estrogen receptor modulators (SERMs) that can be bound to the estrogen receptor ?, therefore prevent bonding between estrogen and estrogen receptor ?. Methods: This research used molecular docking analysis of family Fabaceaes Phytochemistry as an inhibitor of estrogen receptor ? activation. This study was observational bioinformatics study to observe interaction between family Fabaceaes phytochemistry and estrogen receptor?. Molecular docking analysis observed binding energy and binding location. This virtual screening analysis was done using PyRx, AutoDock Vina, PyMOL, Open Babel, and UCSF Chimera. Results: We obtained 471 Family Fabaceaes phytochemistry from database, only five compounds that have equal or lower binding energy compared with tamoxifen, that compound werebeta-amyrine (9.6 KJ/Mol), obovatin( 9.6 KJ/Mol), erythrabyssin II (9.6 KJ/Mol), Cajaflavanone (10.2 KJ/Mol), and tomentosanol E (10.5 KJ/Mol). The visualization of binding location analysis showed that only cajaflavanone which have relatively similar binding site location with tamoxifen. Conclusions: Cajaflavanone have a similar characteristic with tamoxifen, and have a potency to be used as partial antagonist of estrogen receptor alpha in breast cancer based molecular docking analysis. However, In vitro and In vivo researchneeded to determine the effectiveness. Keywords: Breast Cancer, Molecular Docking, Fabacea, Tamoxifen, Estrogen Receptor ?
Molecular Docking Analysis of Estrogen Receptor ? to Phytochemistries in Asteraceae Family Compared to Tamoxifen in Breast Cancer Dzulfiar Nasir Umam; Riza Novierta Pesik; Ratna Kusumawati
Nexus Kedokteran Translasional Vol 4, No 2 (2015): Nexus Kedokteran Translasional
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background:Tamoxifen is the first line hormonal therapy for Estrogen Receptor ?(ER?) breast cancer. Some of phytochemistries pose anticancer activities. However, data of those from Asteraceae family in Indonesia are lacking. The aim of this research is to know the binding affinities and binding locations of phytochemistries in Asteraceae family from Indonesia compared to tamoxifen on ER? in breast cancer. Methods: This research wasa bioinformatic study. Subjects were3-dimensional structures ofER?, tamoxifen, and phytochemistriess Asteraceae family obtained from Indonesian HerbalDB database, Pubchem Compound, and Protein Data Bank. Subjects were prepared by Chimera 1.10 and Open Babel. Tamoxifen was docked on ER? by AutoDock Vina to know its binding affinities of ligand-receptor complex, compared to the other chosen ligands. Binding locations of ligand-reseptor were visualized by Pymol 1.7.2. Results: The docking results showed four phytochemistriess binding affinities whichwere stronger than tamoxifen (-9.6 kcal/mol), such as lappadilactone, friedelin, benperidol, and beta-amyrin. The visualization results showed that lappadilactone, friedelin, benperidol, beta-amyrin, taraxerol, andepifriedelanol had similar binding areas totamoxifen on ER?. Lappadilactone had hydrogen bond with Tyr526 and benperidol had hydrogen bond with Trp383 on ER?. Conclusions:Lappadilactone and benperidol have stronger binding affinities than tamoxifen and they have hydrogen bond with ER?, but not in active sites of ER?. Therefore, lappadilactone and benperidol may have ability to inhibit ER? activities computationally. Keywords: Estrogen receptor ?, molecular docking, phytocemistry, tamoxifen.
Konflik Kepentingan antara Manajemen dan Pemilik Perusahaan Yulekhah Ariyanti; Ratna Kusumawati
AKSES: Jurnal Ekonomi dan Bisnis Vol 1, No 1 (2006)
Publisher : Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (160.447 KB) | DOI: 10.31942/akses.v1i1.451

Abstract

The article explored the effect of separation between share holder and management  which could make agency problem. The problem was  caused by the agent and the principal as economic agent so they tried holding their interest  and doing moral hazard  for protecting their interest.