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Puspitasari, Dewi Fitriani
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health

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Journal : Jurnal Buana Farma

 1 
PENGARUH KONSENTRASI BEESWAX SEBAGAI EMULGATOR PADA KARAKTERISTIK DAN STABILITAS FISIK SEDIAAN KRIM PATI BENGKUANG (Pachyrhizus erosus L.) Puspitasari, Dewi Fitriani; Ratih, Sekar Wida
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1290

Abstract

Starch of bengkuang tuber (Pachyrhizus erosus L.) has antioxidant activity, is able to provide moisture, antiaging , relieve inflammation so that it is efficacious to prevent skin cell damage due to free radicals. The formulation of bengkuang starch in cream form is expected to make it easier to use. The main component that affects the physical characteristics of a cream preparation is the emulgator. Beeswax is an emulgator that can improve cream consistency and stabilise the preparation. This study aims to determine the effect of different concentrations of beeswax on the physical characteristics and stability of bengkuang starch cream preparation. The research method begins with the collection of starch which is done by filtering the juice of the bengkuang tuber. The results of the filter were precipitated 24 hours and then the precipitate was dried. The cream was made in 3 formulas namely FI, FII and FIII with variations of beeswax 5, 10 and 15%, then tested for characteristics and physical stability. The results showed that increasing the concentration of beeswax caused the viscosity value of the cream preparation to increase, the spreadability value decreased and the adhesion value increased. The concentration of beeswax also affects the pH value of the preparation, namely the higher the concentration of beeswax, the pH value increases. The results of the physical stability test using the cycling test method for 6 cycles show that the cream preparations that are still stable are formula II and III.
POTENSI FRAKSI DAUN SIRIH MERAH (Piper crocatum) MENGHAMBAT JAMUR PENYEBAB KEPUTIHAN Puspitasari, Dewi Fitriani; Kresnawati, Yani; Sebtiana K, Rika
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1547

Abstract

Vaginal discharge is a condition suffered by many women, both adolescents and menopausal women. This is due to hormonal changes and imbalances in normal flora, as well as fungal infections such as Candida albicans. Several studies have tested the activity of red betel leaf fractions against Candida albicans using 70% and 80% ethanol solvents in the extraction process. This study aims to test the activity of n-hexane and ethyl acetate fractions of red betel leaf against Candida albicans extracted using 96% ethanol solvent. The study began with extraction using 96% ethanol solvent, followed by phytochemical screening of the extract. Fractionation was carried out with n-hexane, ethyl acetate, and water solvents. The n-hexane and ethyl acetate fractions were then tested for their activity against Candida albicans. The results showed that the n-hexane fraction exhibited greater inhibitory activity against Candida albicans than the ethyl acetate fraction (p<0.05), indicating that the n-hexane fraction is more potent in inhibiting Candida albicans.
Co-Authors Achmad Wildan Ariani, Lilies Wahyu Auliya, Jeaniva Putri Kresnawati, Yani Novitasari, Aprilia Donna Pratiwi, Arik Dian Eka Ramona, Dewi Ratih, Sekar Wida Sebtiana K, Rika Sundoro, Aries Koes Utami, Rani Nur Ayu Wulandari Wulandari