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All Journal Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry
Rizal, Moh. Basroni
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Particle size analysis of yellowfin tuna (Thunnus albacares) skin collagen powder using papain-soluble collagen method with varying NaCl concentrations: an experimental laboratory Fatryana, Destya Arizha; Rahmitasari, Fitria; Nanik K., Chaterina Diyah; Rizal, Moh. Basroni; Winias, Saka
Padjadjaran Journal of Dentistry Vol 36, No 2 (2024): July 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no2.54588

Abstract

ABSTRACTIntroduction: The skin of yellowfin tuna (Thunnus albacares) contains high protein, which could potentially be a halal collagen product. Collagen extraction using the papain-soluble collagen method has the advantage of producing a higher collagen yield compared to the acid method. Particle size, one of the physical properties of collagen, plays a crucial role in its efficacy in dentistry. This study aims to analyze the particle size of collagen powder synthesized   from Thunnus albacares skin using the papain-soluble collagen method, with varying concentrations of NaCl. Methods: Type of research is an experimental laboratory. Thunnus albacares skin was synthesized by chopping, cleaning, and soaking in a 0.1 M NaOH solution. The extraction process used the enzyme papain and 0.5 M of acetic acid. Samples were divided into four groups, each with different concentrations of NaCL: 0, no NaCL;, 0.9 M NaCl, 1.3 M NaCl, and 1.7 M NaCl. After centrifugation, the samples were freeze-dried. The particle size of collagen powder was measured using a Particle Size Analyzer test tool. The data collected was then analyzed using the Mann-Whitney test. Results: Particle size distributions are as follows: K group (3.36 nm), P1 (1.842 nm), P2 (3.36 nm), and P3 (10.12 nm). There is a significant difference in groups K-P1 and P3, P1-P2 and P3, and P2-P3 (p<0.05). However, there is no significant difference in groups K-P2 (p>0.05). Conclusion: Particle size of this research produced nano-sized collagen powder, with the lowest particle size observed in the 0.9 M NaCl group, measuring at 1.842 nm. The particle size increased in the group without NaCl and in the 1.3 M NaCl group at 3.36 nm, and reached the highest value in the 1.7 M NaCl group at 10.12 nm. 
Prevalence of systemic risk factors in chronic periodontitis patients at Haji regional public hospital in East Java Province: a cross-sectional study Nilawati, Nina; Sumekar, Henu; Nafiah, Nafiah; Rizal, Moh. Basroni
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 37, No 3 (2025): Desember 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v37i3.64891

Abstract

Introduction: Periodontal disease is a chronic inflammatory disease that affects the tooth-supporting tissues  and is often associated with various systemic disorders. Understanding this relationship is essential for comprehensive dental management. The aim of this study was to determine the prevalence of systemic risk factors among patients with chronic periodontitis at Haji Regional Public Hospital, East Java Province. Methods: A descriptive observational study with a cross-sectional design involving 108 patients diagnosed with chronic periodontitis. Data were collected from electronic medical records and analyzed descriptively using cross-tabulation. Results: The majority of patients were older adults (51.9%) and female (59.3%). A total of 78.7% had systemic conditions, the most common being hypertension and diabetes mellitus. Conclusion: Most chronic periodontitis patients had systemic conditions, particularly among older adults. These findings emphasize the importance of an interdisciplinary approach in periodontal care.Prevalensi faktor risiko sistemik pada pasien periodontitis kronis di Rumah Sakit Umum Daerah Haji Provinsi Jawa Timur: Studi cross sectional Pendahuluan: Penyakit periodontal merupakan penyakit inflamasi kronis yang memengaruhi jaringan penyangga gigi dan sering kali berhubungan dengan berbagai gangguan sistemik. Memahami hubungan ini sangat penting untuk penatalaksanaan kedokteran gigi yang komprehensif. Penelitian ini bertujuan untuk mengetahui prevalensi faktor risiko sistemik pada pasien dengan periodontitis kronis di Rumah sakit Umum Daerah Haji Provinsi Jawa Timur. Metode: Penelitian observasional deskriptif dengan desain potong lintang yang melibatkan 108 pasien yang didiagnosis dengan periodontitis kronis. Data dikumpulkan dari dokumentasi medis elektronik dan dianalisis secara deskriptif menggunakan tabel krostab. Hasil: Mayoritas pasien berusia lanjut (51,9%) dan berjenis kelamin perempuan (59,3%). Sebanyak 78,7% memiliki kondisi sistemik, yang paling umum adalah hipertensi dan diabetes melitus. Simpulan: Sebagian besar pasien dengan periodontitis kronis memiliki kondisi sistemik, terutama pada kelompok usia lanjut. Temuan ini menekankan pentingnya pendekatan interdisipliner dalam perawatan periodontal.
Co-Authors Fatryana, Destya Arizha Fitria Rahmitasari Henu Sumekar, Henu Nafiah, Nafiah Nanik K., Chaterina Diyah Nilawati, Nina Saka Winias