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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Jurnal Ilmiah Nusantara
Astuti, Lelly Winduhani
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Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health Social Sciences

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STUDI EFEKTIVITAS OBAT ANALGESIK PADA PASIEN RAWAT INAP CLOSE FRAKTUR MENGGUNAKAN METODE VISUAl ANALOG SCALE DI RSUD GAMBIRAN KOTA KEDIRI Fitria Wahyuning Wulan; Rilawati, Fentyana Dwi; Astuti, Lelly Winduhani; Nisa, Hanni Cholifatu
SAINS INDONESIANA Vol. 2 No. 3 (2024): Vol. 2, No. 3 Edisi Juni 2024
Publisher : Gamma Publishing

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Abstract

Abstrak Fraktur merupakan kondisi dimana tulang keras atau tulang rawan mengalami kerusakan. Salah satu jenis fraktur adalah close fraktur. Saat seseorang mengalami close fraktur akan mengalami nyeri. Pemberian obat analgesik merupakan salah satu cara untuk mengurangi rasa nyeri pasien close fraktur. Penelitian ini bertujuan untuk mengetahui efektivitas obat analgesik pada pasien rawat inap close fraktur di RSUD Gambiran Kota Kediri. Metode yang digunakan adalah deskriptif observasional dengan desain penelitian secara retrospektif. Pengukuran skala nyeri pada pasien menggunakan skala Visual Analog Scale pada data rekam medis. Data diambil dari 95 pasien. Dari hasil penelitian terdapat 3 janis pemberian obat analgesik pada pasien close fraktur yaitu metamizole dan ketorolac tunggal dengan rata-rata VAS sebelum pemberian obat 5 yaitu nyeri sedang sangat menyusahkan kemudian setelah pemberian obat menjadi 4 yaitu nyeri sedang menyusahkan, dan kombinasi metamizol + ketorolac dengan rata-rata VAS sebelum pemberian obat 6 nyeri berat yang masuk kedalam kategori sedang kemudian setelah diberikan obat menjadi 4 yaitu nyeri sedang menyusahkan. Penelitian ini menunjukkan bahwa terdapat keefektivitasan obat analgesik dalam menurunkan nyeri pada pasien close fraktur di RSUD Gambiran Kota Kediri dilihat dari derajat nyeri yang dirasakan pasien berkurang setelah pemberian obat analgesik dan hasil uji wilcoxon dengan nilai p-value 0,000 < 0,05.
INPATIENT ANTITHROMBOTIC THERAPY FOR MYOCARDIAL INFARCTION : RETROSPECTIVE STUDY Fajriyah, Shofiatul; Nur Rohmah, Dilla Salwa; Astuti, Lelly Winduhani; Rilawati, Fentyana Dwi; Wulan, Fitria Wahyuning; Widyaningrum, Esti Ambar
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.762

Abstract

Myocardial infarction (MI), a subtype of coronary heart disease (CHD), is still a major cause of morbidity and mortality around the world. Non-ST-segment elevation MI (NSTEMI) is more common than ST-segment elevation MI (STEMI). Antithrombotic therapy, including antiplatelet and anticoagulant agents, is essential in MI management to prevent thrombus formation and reduce ischemic complications. Although international and national clinical guidelines (PERKI and ACC/AHA) provide recommendations tailored to MI type and patient factors, discrepancies in clinical practice, especially in developing countries, may impact treatment outcomes. This retrospective descriptive study aimed to evaluate the use and appropriateness of antithrombotic therapy in NSTEMI and STEMI patients at Hospital X, Kediri City, in 2018. Data were collected from medical records of hospitalized acute myocardial infarction (AMI) patients. Aspirin combined with clopidogrel was the most commonly used regimen for NSTEMI, whereas STEMI patients frequently received aspirin, clopidogrel, and enoxaparin; fibrinolytics were administered in nine STEMI cases. Dosage evaluation showed compliance with guidelines in NSTEMI patients, while 36.84% of STEMI patients, particularly those receiving enoxaparin, were given incorrect dosages. These findings highlight the need for improved adherence to clinical guidelines to optimize antithrombotic therapy outcomes in MI management
Correlation Between the Number of Drugs Prescribed and Potentially Inappropriate Medication (PIMS) Based on Beers Criteria in Geriatric Hypertension Outpatients at Dr. Soedomo Hospital in Trenggalek: Hubungan Jumlah Obat terhadap Potentially Inappropriate Medication (PIMS) Berdasarkan Beers Criteria pada Pasien Hipertensi Geriatri Rawat Jalan Rsud Dr. Soedomo Trenggalek Widyaningrum, Esti Ambar; PDW, Kumala Sari; Astuti, Lelly Winduhani; Suhartatik, Sri; Rimawati, Rimawati; Sari, Eka Kartika
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15671

Abstract

Background: Geriatric patients are elderly people who have various diseases and or problems as a result of diminished organ, psychological, social, economic, and environmental functioning and who require integrated health treatments from a multidisciplinary team. Uncontrolled hypertension can lead to complications such as stroke, CHD, and kidney failure. The more incidence of complications, causing the geriatrics to get more drugs (polypharmacy). Polypharmacy is one of the risk factors for the occurrence of Potentially Inappropriate Medication (PIMs) that often occurs in geriatric patients. The 2019 Beers Criteria is one of the clear criteria that can be used to determine the prevalence of PIMs in geriatric individuals. Objectives: The objective of this study was to see if there was a correlation between the number of drugs administered to hypertensive geriatric outpatients at Dr. Soedomo General Hospital in Trenggalek and the incidence of PIMs. This study employed an observational study with an analytical approach and retrospective. This study included a sample of 85 prescriptions for outpatient geriatric hypertension outpatient at Dr. Soedomo General Hospital in the period October - December 2020 taken using the purposive sampling technique. Data were analyzed using the C contingency coefficient correlation test. Results: 67,1% of prescriptions contained ≥ 5 kinds of drugs and 32,9% of prescriptions contained < 5 kinds of drugs. Based on the incidence of PIMs, there were 97.6% of prescriptions for PIMs and 2.4% of prescriptions without PIMs. The C contingency coefficient correlation test shows the correlation coefficient (r) of 0.216 with a positive direction and p-value = 0.041. Conclusions: The number of drugs has a significant correlation and can cause the incidence of PIMs in geriatric patients with weak correlation strength. Collaboration between pharmacists and doctors is needed to provide the best therapy to patients, to maximize the role of pharmacists in monitoring drug use in geriatric patients at Dr. Soedomo Hospital in Trenggalek.
Co-Authors Eka Kartika Sari Esti Ambar Widyaningrum Fitria Wahyuning Wulan Nisa, Hanni Cholifatu Nur Rohmah, Dilla Salwa PDW, Kumala Sari Rilawati, Fentyana Dwi Rimawati, Rimawati Shofiatul Fajriyah Suhartatik, Sri Wulan, Fitria Wahyuning