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Analisis Faktor-Faktor yang Mempengaruhi Kejadian Potentially Inappropriate Medications (PIMs) pada Pasien Geriatri Rawat Inap RSUD Dr. Soedomo Trenggalek Widyaningrum, Esti Ambar; Rizky, Fara Nikhmatul; Irawati, Renny Nur Satya; Fajriyah, Shofiatul; Rilawati, Fentyana Dwi; Kurniawati, Evi; Lestari, Tri Puji
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 17 No. 1 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i1.271

Abstract

Background: Geriatric patients are elderly patients with multiple diseases. Geriatric patients have more comorbidities and often receive polypharmacy prescriptions. PIMs have been identified in many elderly patients. One of the explicit criteria that can be used to identify the incidence of PIMs in geriatric patients is the Beers Criteria. Objective: To determine the frequency of PIMs and the factors that can influence the occurrence of PIMs based on the Beers Criteria in hospitalized geriatric patients at RSUD Dr. Soedomo Trenggalek. Method: This research uses a type of research with a retrospective observational analytical approach. The sampling technique used was purposive sampling with a total sample of 312 medical records.  Inclusion criteria: age ≥ 65 years and exclusion: incomplete medical record data. Results: The most common characteristic profiles were male gender (62%), elderly (65-74 years) 69%, type of BPJS service (87%), main disease with the cardiovascular system (31%), number of diseases 2 (43%) and the number of drugs 6-10 drugs (50%). There was an incidence of PIMs of 78.53%. The factors gender, age, type of service, main diagnosis have a p value ≥ 0.05, while the number of diseases and medications have a p value ≤ 0.05. Conclusion: There is an incidence of PIMs in hospitalized geriatric patients of 78.53% with the number of diseases and number of medications influencing the incidence of PIMs in hospitalized geriatric patients.
STUDI EFEKTIVITAS OBAT ANALGESIK PADA PASIEN RAWAT INAP CLOSE FRAKTUR MENGGUNAKAN METODE VISUAl ANALOG SCALE DI RSUD GAMBIRAN KOTA KEDIRI Fitria Wahyuning Wulan; Rilawati, Fentyana Dwi; Astuti, Lelly Winduhani; Nisa, Hanni Cholifatu
SAINS INDONESIANA Vol. 2 No. 3 (2024): Vol. 2, No. 3 Edisi Juni 2024
Publisher : Gamma Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstrak Fraktur merupakan kondisi dimana tulang keras atau tulang rawan mengalami kerusakan. Salah satu jenis fraktur adalah close fraktur. Saat seseorang mengalami close fraktur akan mengalami nyeri. Pemberian obat analgesik merupakan salah satu cara untuk mengurangi rasa nyeri pasien close fraktur. Penelitian ini bertujuan untuk mengetahui efektivitas obat analgesik pada pasien rawat inap close fraktur di RSUD Gambiran Kota Kediri. Metode yang digunakan adalah deskriptif observasional dengan desain penelitian secara retrospektif. Pengukuran skala nyeri pada pasien menggunakan skala Visual Analog Scale pada data rekam medis. Data diambil dari 95 pasien. Dari hasil penelitian terdapat 3 janis pemberian obat analgesik pada pasien close fraktur yaitu metamizole dan ketorolac tunggal dengan rata-rata VAS sebelum pemberian obat 5 yaitu nyeri sedang sangat menyusahkan kemudian setelah pemberian obat menjadi 4 yaitu nyeri sedang menyusahkan, dan kombinasi metamizol + ketorolac dengan rata-rata VAS sebelum pemberian obat 6 nyeri berat yang masuk kedalam kategori sedang kemudian setelah diberikan obat menjadi 4 yaitu nyeri sedang menyusahkan. Penelitian ini menunjukkan bahwa terdapat keefektivitasan obat analgesik dalam menurunkan nyeri pada pasien close fraktur di RSUD Gambiran Kota Kediri dilihat dari derajat nyeri yang dirasakan pasien berkurang setelah pemberian obat analgesik dan hasil uji wilcoxon dengan nilai p-value 0,000 < 0,05.
INPATIENT ANTITHROMBOTIC THERAPY FOR MYOCARDIAL INFARCTION : RETROSPECTIVE STUDY Fajriyah, Shofiatul; Nur Rohmah, Dilla Salwa; Astuti, Lelly Winduhani; Rilawati, Fentyana Dwi; Wulan, Fitria Wahyuning; Widyaningrum, Esti Ambar
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.762

Abstract

Myocardial infarction (MI), a subtype of coronary heart disease (CHD), is still a major cause of morbidity and mortality around the world. Non-ST-segment elevation MI (NSTEMI) is more common than ST-segment elevation MI (STEMI). Antithrombotic therapy, including antiplatelet and anticoagulant agents, is essential in MI management to prevent thrombus formation and reduce ischemic complications. Although international and national clinical guidelines (PERKI and ACC/AHA) provide recommendations tailored to MI type and patient factors, discrepancies in clinical practice, especially in developing countries, may impact treatment outcomes. This retrospective descriptive study aimed to evaluate the use and appropriateness of antithrombotic therapy in NSTEMI and STEMI patients at Hospital X, Kediri City, in 2018. Data were collected from medical records of hospitalized acute myocardial infarction (AMI) patients. Aspirin combined with clopidogrel was the most commonly used regimen for NSTEMI, whereas STEMI patients frequently received aspirin, clopidogrel, and enoxaparin; fibrinolytics were administered in nine STEMI cases. Dosage evaluation showed compliance with guidelines in NSTEMI patients, while 36.84% of STEMI patients, particularly those receiving enoxaparin, were given incorrect dosages. These findings highlight the need for improved adherence to clinical guidelines to optimize antithrombotic therapy outcomes in MI management