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All Journal Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Jurnal Medika Nusantara Jurnal Ilmiah Nusantara
Fitria Wahyuning Wulan
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Computer Science & IT Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Analisis Kejadian Interaksi Obat pada Pasien Skizofrenia di RSUD Dr. Iskak Tulungagung Fitria Wahyuning Wulan; Wenni Arina Dewi
Jurnal Medika Nusantara Vol. 2 No. 1 (2024): Februari : Jurnal Medika Nusantara
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/medika.v2i1.922

Abstract

Schizophrenia is a syndrome with multiple ethology, outcome differ depending on the chronic course of the diseases, and the balance of physical, genetic also influences in the country. Schizophrenia patients have psychotic symptoms, so the main psychopharmacology given to schizophrenia patients is antipsychotics. The main treatment for schizophrenia is antipsychotic drugs, many schizophrenia patients receive combination therapy with antipsychotic drugs. Drug interactions generally refer to changes in drug response resulting from a patient's exposure to a drug or other substance. The potential severity of interactions is important for evaluating the risks and benefits of alternative treatments. Severity is classified into mild severity (effects are usually mild), moderate severity (new effects may cause severity of the patient's disease), and severe severity (possibly life-threatening or may cause permanent damage). This study aims to determine drug interactions and treatment patterns regarding pharmacokinetic and pharmacodynamics interactions in schizophrenia patients at Iskak Tulungagung Hospital. The research method uses analytics with retrospective data collection. The research sample consisted of 48 respondents in the categories mild (2%), moderate (78%), and severe (20%). The results display is potential for drug interactions in the form of pharmacodynamics potential (97%) which dominates more than pharmacokinetic potential (3%).
Pasien Infark Miokard Akut pada Studi Penggunaan Obat Anti Platelet di RSUD Gambiran Kota Kediri Lelly Winduhani Astuti; Fitria Wahyuning Wulan; Nadya Bella Donna
Jurnal Medika Nusantara Vol. 2 No. 1 (2024): Februari : Jurnal Medika Nusantara
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/medika.v2i1.923

Abstract

The purpose of this study was to determine the pattern of drug use, potential interactions, and side effects of antiplatelet drugs in acute myocardial infarction patients in inpatient installations to reduce morbidity and mortality rates at Gambiran Hospital, Kediri City. This study is a non-experimental study with descriptive research design and retrospective data collection, data collection using purposive sampling method. Retrospective data collection based on medical record data of patients with acute myocardial infarction, this research was conducted from January to December 2020, so that the pattern of use of anti-platelet drugs in patients with acute myocardial infarction was a combination of aspirin 80 mg 1x1 with clopidogrel 75mg 1x1 (93%), with the route of drug administration orally. Analysis of potential drug interactions was carried out using the Drugs Interaction Checker and obtained 4 occurrences of major potential interactions and 10 occurrences of moderate potential interactions. The desired potential drug interaction was to prevent platelet aggregation. There was an undesirable potential drug interaction related to decreased antihypertensive effect of the drug, while potential drug interactions in the form of gastrointestinal bleeding and decreased renal function could not be determined.
STUDI EFEKTIVITAS OBAT ANALGESIK PADA PASIEN RAWAT INAP CLOSE FRAKTUR MENGGUNAKAN METODE VISUAl ANALOG SCALE DI RSUD GAMBIRAN KOTA KEDIRI Fitria Wahyuning Wulan; Rilawati, Fentyana Dwi; Astuti, Lelly Winduhani; Nisa, Hanni Cholifatu
SAINS INDONESIANA Vol. 2 No. 3 (2024): Vol. 2, No. 3 Edisi Juni 2024
Publisher : Gamma Publishing

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Abstract

Abstrak Fraktur merupakan kondisi dimana tulang keras atau tulang rawan mengalami kerusakan. Salah satu jenis fraktur adalah close fraktur. Saat seseorang mengalami close fraktur akan mengalami nyeri. Pemberian obat analgesik merupakan salah satu cara untuk mengurangi rasa nyeri pasien close fraktur. Penelitian ini bertujuan untuk mengetahui efektivitas obat analgesik pada pasien rawat inap close fraktur di RSUD Gambiran Kota Kediri. Metode yang digunakan adalah deskriptif observasional dengan desain penelitian secara retrospektif. Pengukuran skala nyeri pada pasien menggunakan skala Visual Analog Scale pada data rekam medis. Data diambil dari 95 pasien. Dari hasil penelitian terdapat 3 janis pemberian obat analgesik pada pasien close fraktur yaitu metamizole dan ketorolac tunggal dengan rata-rata VAS sebelum pemberian obat 5 yaitu nyeri sedang sangat menyusahkan kemudian setelah pemberian obat menjadi 4 yaitu nyeri sedang menyusahkan, dan kombinasi metamizol + ketorolac dengan rata-rata VAS sebelum pemberian obat 6 nyeri berat yang masuk kedalam kategori sedang kemudian setelah diberikan obat menjadi 4 yaitu nyeri sedang menyusahkan. Penelitian ini menunjukkan bahwa terdapat keefektivitasan obat analgesik dalam menurunkan nyeri pada pasien close fraktur di RSUD Gambiran Kota Kediri dilihat dari derajat nyeri yang dirasakan pasien berkurang setelah pemberian obat analgesik dan hasil uji wilcoxon dengan nilai p-value 0,000 < 0,05.
Evaluasi Rasionalitas Insulin Pada Pasien Diabetes Mellitus Tipe 2 Rawat Jalan di RSUD Kota Madiun Periode 2022 Fitria Wahyuning Wulan; Lelly Winduhani Astuti; Fentyana Dwi Rilawati; Akbar Firdaus Syam
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 2 No. 3 (2024): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v2i3.4054

Abstract

Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to defects in insulin secretion, insulin action or both. Diabetes mellitus (DM) is currently a global health threat. Various epidemiological studies have shown an increase in the incidence and prevalence of DM in the world. Based on data from the profile of the East Java Health Office in 2021, it is estimated that DM patients in Madiun City rank fourth in the East Java region. . Objective: This research was conducted to determine the evaluation of the rationality of insulin in type 2 DM patients in the Outpatient Hospital of Madiun City Hospital for the period 2022. Methods: This research method is in the form of an observational research, retrospective data collection in the form of medical records of history of type 2 diabetes mellitus patients at Outpatient Hospital at RSUD Madison City. The total population in this study in the period January - December 2022 was 165 patients. Results: From the 62 type 2 DM patients who were outpatients at Madiun City Regional Hospital, it was found that 14.52% using single insulin and 12.90% used Detemir insulin. The use of the insulin combination was 85.48% and the Detemir – Aspart insulin combination was 58.06%. Conclusion: Evaluation of the rationality of insulin use showed that the correct drug was 100% and the correct dose was 93,55%.
Co-Authors Akbar Firdaus Syam Astuti, Lelly Winduhani Fentyana Dwi Rilawati Lelly Winduhani Astuti Nadya Bella Donna Nisa, Hanni Cholifatu Rilawati, Fentyana Dwi Wenni Arina Dewi