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All Journal Chimica et Natura Acta Jurnal Farmasi Higea Journal of Experimental and Clinical Pharmacy (JECP)
Sriwijaya, Reza Agung
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Evaluasi Mutu Penyimpanan Obat di Instalasi Farmasi RS. X Palembang Berdasarkan Standart Nasional Akreditasi Rumah Sakit Sriwijaya, Reza Agung; Fatoni, Ahmad; Anggraini, Anggraini
Journal of Experimental and Clinical Pharmacy (JECP) Vol 2, No 1 (2022): February 2022
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v2i1.371

Abstract

Pengelolaan  sediaan farmasi, alat kesehatan, dan Bahan Medis Habis Pakai (BMHP),salah satunya penyimpanan obat harus dapat menjamin kualitas dan keamanan sesuai dengan persyaratan kefarmasian. Penelitian ini bertujuan untuk mengetahui mutu penyimpanan obat berdasarkan Standar Akreditasi Nasional Rumah Sakit (SNARS) Jenis penelitian ini adalah non eksperimental,deskriptif dengan pengamatan langsung terhadap fasilitas penyimpanan obat. Pengumpulan data dengan cara pengamatan langsung dan wawancara dengan apoteker  di Instalasi Farmasi bagian penyimpanan obat rumah sakit X menggunakan lembar chek list ditabel pengamatan, kemudian dihitung persentasenya. hasil didapat Standar Operasional Prosedur Penyimpanan sebesar 100% (baik), kondisi sarana dan prasarana penyimpanan kesesuaian sebesar 93% (Baik) dan pengaturan penyimpanan obat kesesuaian sebesar 96% (Baik).Management of pharmaceutical preparations, medical devices, and medical consumables, one of which is drug storage must be able to guarantee quality and safety by pharmaceutical requirements. This study aims to determine the quality of drug storage based on the National Hospital Accreditation Standard (SNARS). This type of research is non-experimental, descriptive with direct observation of drug storage facilities. Collecting data by direct observation and interviews with pharmacists at the Warehouse divison of Pharmacy Installation of hospital X using a checklist sheet in the observation table, then the percentage is calculated. The results obtained are Standard Operating Procedures for Storage of 100% (good), the condition of facilities and infrastructure for storage of conformity is 93% (Good) and drug storage arrangements are of conformity of 96% (Good).
AKTIVITAS ANTIDIABETES DARI FRAKSI ETIL ASETAT BUAH TAKOKAK (Solanum torvum Swartz) TERHADAP MENCIT PUTIH JANTAN YANG DIINDUKSI ALOKSAN Erjon, Erjon; Febriyanti, Dita; Sriwijaya, Reza Agung; Sari, Ema Ratna; Lely, Nilda
Jurnal Farmasi Higea Vol 17, No 1 (2025)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v17i1.692

Abstract

Diabetes mellitus adalah penyakit metabolik, yang ditandai dengan peningkatan kadar gula darah melebihi nilai normal. Buah tokokak (Solanum torvum Swartz) dilaporkan memiliki aktivitas sebagai antidiabetes. Penelitian ini bertujuan untuk mengevaluasi aktivitas antidiabetes dari fraksi etil asetat buah takokak pada mencit putih Jantan model diabetes. Dosis fraksi etil asetat buah takokak yang digunakan adalah 100, 200, dan 400 mg/kgbb. Sediaan uji diberikan dalam dosis tunggal selama 14 hari. Parameter pengukuran adalah presentase penurunan kadar gula darah dari mencit model diabetes. Dari hasil penelitian menunjukkan bahwa fraksi etil asetat buah takokak dengan dosis 100, 200, dan 400 mg/kgbb berpotensi sebagai antidiabetik. Peningkatan dosis pemberian fraksi etil asetat buah takokak berkorelasi positif yang sangat kuat terhadap peningkatan efek antidiabetes.
Biosynthesis, Characterization of Curcumin-Capped Zno-Cuo and Chitosan-Curcumin-Capped Zno-Cuo based Nanomaterial as Antibacterial Agent of Escherichia coli Fatoni, Ahmad; Umli, Afnita Fatmawati; Sriwijaya, Reza Agung; Hilma, Hilma; Hidayati, Nurlisa
Chimica et Natura Acta Vol 13, No 3 (2025)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v13.n3.62946

Abstract

The biofabrication of the chitosan-curcumin-capped ZnO-CuO and curcumin-capped ZnO-CuO nanoparticles, as well as their ability to combat Escherichia coli bacteria, were the focus of this study. Fourier-Transform Infrared (FTIR) spectroscopy, X-ray diffraction (XRD), and Scanning Electron Microscopy (SEM) were used to examine the chitosan-curcumin-capped ZnO-CuO and curcumin-capped ZnO-CuO nanoparticles, respectively. Both were evaluated using the agar diffusion method as antibacterials against Escherichia coli. Results of analysis with FTIR, between 500 and 700 cm⁻¹, the functional group of Cu-O or Zn-O was seen at its highest point. The functional group of Cu-O and Zn-O in curcumin-capped ZnO-CuO was detected at wavenumber of 621 cm⁻¹ and 507 cm⁻¹, respectively. In chitosan-curcumin-capped ZnO-CuO, the wave numbers of the Cu-O and Zn-O groups were observed at 619 and 653 cm-1 respectively.  According to XRD analysis results, the chitosan-curcumin-capped ZnO-CuO and curcumin-capped ZnO-CuO nanoparticles' crystalline shapes are demonstrated by their respective crystallite sizes of 12.58 and 1.88 nm. Based on the results of analysis with SEM, curcumin-capped ZnO-CuO and chitosan-curcumin-capped ZnO-CuO nanoparticles have a dense surface structure. The average diameter of inhibition zone (clear zone) produced by chit-cur-ZnO-CuO nanoparticles is 14.61 mm, while the clear zone produced by cur-ZnO-CuO nanoparticles is 9.52 mm. Chit-cur-ZnO-CuO has superior antibacterial qualities to cur-ZnO-CuO nanoparticles.
Co-Authors Ahmad Fatoni Anggraini Anggraini Erjon, Erjon febriyanti, dita Hilma, Hilma Nurlisa Hidayati Ramadani, Anggi Sari, Ema Ratna Umli, Afnita Fatmawati Wahyuni, Yenni Sri