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All Journal Jurnal Pengolahan Hasil Perikanan Indonesia SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Amerta Nutrition Indonesian Journal of Global Health research Journal of Advanced Multidisciplinary Research Jurnal Pengabdian Masyarakat Kedokteran
Utami, Kamilia Dwi
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Pengaruh Kombinasi Ekstrak Belimbing Wuluh (Averrhoa Bilimbi L.) dan Ekstrak Kunyit (Curcuma Longa L.) terhadap Kadar Low Density Lipoprotein: Effect of Combination of Averrhoa Bilimbi Extract and Curcuma Longa Extract on Low Density Lipoprotein Levels in Rats Fed a High Fat Diet Fatikhasari, Amalia Nurazima; Yuniarifa, Conita; Utami, Kamilia Dwi; Riza, Mohamad; Soetoko, Anita Soraya
Amerta Nutrition Vol. 8 No. 3 (2024): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v8i3.2024.363-367

Abstract

Background: Hypercholesterolemia is a state of total blood cholesterol levels transported by LDL exceeding normal limits. As a result, it can clog blood vessels, and this condition is a risk factor for CHD. Alternative medicine includes flavonoids in Averrhoa bilimbi (belimbing wuluh) known to reduce cholesterol and LDL levels, and curcumin in turmeric known to reduce fat absorption and increase fat excretion. Objectives: The aim of this study was to analyze the combined effect of bilimbi fruit and turmeric extracts on LDL levels. Methods: This experimental research used post-test only with a control group design involving male Wistar rats divided into 6 (six) random groups. Group KN (standard feed, aquadest for 28 days), K- (high-fat feed for 14 days, followed by standard feed and aquadest), K+ (high-fat feed for 14 days, followed by standard feed, aquadest, and simvastatin 0.18mg/200 g BW/day), P1 (high-fat feed for 14 days, followed by standard feed, aquadest and extracts of bilimbi fruit and turmeric extract at a dose of 240: 270 mg/200 g BW/day), P2 (high-fat diet for 14 days, followed by standard feed, distilled water and bilimbi fruit and turmeric extract at a dose of 360: 175 mg/200 g BW/day), P3 (high-fat diet for 14 days, followed by standard feed, distilled water and extracts of bilimbi fruit and turmeric at a dose of 120: 405 mg/200 g BW/day). The determination of LDL levels was done through a direct method using a spectrophotometer with a wavelength of 550 nm. Results: The mean LDL levels were KN (53.60 ± 10.69) mg/dL, K- (193.40 ± 16.86) mg/dL, K+ (100.20 ± 42.48) mg/dL, P1 (118.00 ± 64.71) mg/dL, P2 (104.00 ± 45.28) mg/dL, P3 (78.00 ± 4.69) mg/dL. The data received was analyzed using the Kruskal-Wallis test. Then, the results obtained differences in LDL levels between various groups (p<0.001). Subsequently, it was continued with the Mann-Whitney test on KN compared to K-, K+, P1, P2, P3 indicating p=0.009. As a result, it was found a significant difference in LDL levels between KN and K-, K+, P1, P2, and P3. Conclusions: This research concludes that providing a mixture of bilimbi fruit extract and turmeric extract can reduce LDL levels.
Upaya Peningkatan Pengetahuan tentang Bahaya Merokok pada Siswa SDIT Permata Bunda Mranggen, Demak Utami, Kamilia Dwi; Amanda, Qorry; Amelia, Amelia
Jurnal Pengabdian Masyarakat Kedokteran Vol 3, No 2 (2024): Mei
Publisher : Fakultas Kedokteran, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/abdimasku.3.2.57-67

Abstract

Jumlah perokok laki-laki di Demak, usia 15-24 tahun sebesar 18,8%, 25-34 tahun sejumlah 33,3%, dan 35-44 tahun sebesar 26,77%. Perilaku merokok, tidak terjadi secara tiba-tiba, akan tetapi dimulai sejak anak-anak atau remaja. Berdasarkan observasi dan survei awal yang dilakukan peneliti di SDIT Permata Bunda dan lingkungan sekitar Desa Batursari Mranggen Demak, ada sebagian alumni yang berada di lingkungan keluarga atau teman perokok, mulai tertarik merokok. Perilaku merokok sering terjadi pada siswa laki laki dan terjadi saat berada di luar lingkungan sekolah. Oleh karena itu perlu dilakukan edukasi tentang bahaya merokok kepada siswa. Tujuan pengkajian ini adalah untuk mengetahui tingkat pengetahuan tentang bahaya merokok dan pengaruh penyuluhan bahaya merokok pada siswa SDIT Permata Bunda kelas V dan VI. Penyuluhan dilakukan menggunakan presentasi diselingi video animasi bahaya merokok. Penelitian ini bersifat analitik kuantitatif dengan desain cross sectional, menggunakan alat ukur kuesioner pre-post penyuluhan. Sampel diambil dengan metode total sampling berjumlah 146 responden. Analisis data menggunakan Mc Nemar Didapatkan perbedaan bermakna antara tingkat pengetahuan bahaya merokok di antara nilai pretest dan postest (p<0,05). Pentingnya edukasi merokok, untuk meningkatkan pengetahuan siswa tentang bahaya merokok.In Demak, the prevalence of male smokers varies among age groups, with rates of 18.8% for ages 15-24, 33.3% for ages 25-34, and 26.77% for ages 35-44. According to the 2021 GATS survey, two out of three adult men in the region are smokers. The adoption of smoking behavior typically initiates during childhood or adolescence. Initial observations and surveys conducted by researchers at Permata Bunda Elementary School, within the vicinity of Batursari Mranggen Demak Village, reveal that some alumni are smokers, and their family or friends are showing an increasing interest in smoking. Smoking tendencies are prevalent among male students, particularly outside the school environment, emphasizing the need for comprehensive education on the hazards of smoking.  This study aims to assess the level of knowledge regarding the dangers of smoking and the impact of counseling on SDIT Permata Bunda students in grades V and VI. Counseling sessions utilized presentations combined with animated videos addressing the dangers of smoking. The research follows a quantitative analytical approach with a cross-sectional design, employing a pre-post counseling questionnaire for measurement. A total sampling method was used, encompassing 146 respondents. Data analysis was conducted using the Mc Nemar statistical test. Significant differences were observed between the pretest and posttest scores concerning the knowledge of the dangers of smoking (p<0.05). The study underscores the significance of smoking education in augmenting students' knowledge about the hazards associated with smoking. This emphasizes the need for ongoing efforts to educate students and mitigate the allure of smoking, especially among younger age groups.
Factors affecting quality of life in patients undergoing hemodialysis in Semarang, Indonesia Lusito, Lusito; Utami, Kamilia Dwi; Yuliyanti, Suryani; Nurmalita, Ar-Rahmah; Amaliyah, Laily Rezky
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 16, No 1 (2025): June 2025
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v16i1.39560

Abstract

The quality of life in patients with chronic kidney disease (CKD) reflects how well an individual's needs are met across three physical, psychological, and social dimensions. Measuring a patient's quality of life (QoL) helps evaluate the effectiveness of CKD therapies. This study compares patients' clinical conditions categorised by their quality of life while undergoing hemodialysis therapy for chronic kidney failure. This study compares the clinical conditions of CKD patients undergoing hemodialysis based on their QoL, using a cross-sectional design involving 82 patients from Sultan Agung Islamic Hospital, Semarang. QoL was assessed with the WHOQOL-BREF questionnaire, and demographic data were collected through interviews. Clinical data was sourced from electronic medical records. Logistic regression analysis identified influencing variables on QoL. The sample was predominantly female (62.2%), with most patients over 45 years old, meeting minimum education standards (61%), and 67.1% unemployed. Most identified as Muslim and married, with 98.8% reporting strong family support. While bivariate analysis showed no significant impact of demographic or clinical variables on QoL, multivariate analysis indicated a significant relationship with haemoglobin levels. While other factors like family support and knowledge contribute to well-being, further research with larger, more varied samples is needed to better understand the quality-of-life influences for CKD patients on hemodialysis.
Factors that Influence Medication Compliance in Pulmonary Tuberculosis Patients Nugroho, Bayu M.A; Yuniarifa, Conita; Utami, Kamilia Dwi
Indonesian Journal of Global Health Research Vol 7 No 4 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i4.5884

Abstract

Pulmonary tuberculosis is a chronic infectious disease that has a significant impact on global health, including Indonesia. Bandar I Health Center, Batang Regency was chosen as the research location because it has a low complete rate of taking medication (29.09%). Objective to analyze factors that influence medication compliance in pulmonary tuberculosis patients, including knowledge, attitudes, access to health services, drug side effects, family support, and support from health workers. An analytical observational design with a cross-sectional method. Data were collected through questionnaires from 68 pulmonary tuberculosis patients who met the inclusion criteria. Bivariate analysis used the Chi-Square test to determine the relationship between each independent variable and compliance, while multivariate analysis was performed to determine the dominant influencing factors. The knowledge, attitude, family support, and health worker support had a significant relationship with patient compliance (p < 0.05). Health worker support was a dominant factor with an Exp(B) value of 28.7, which means that patients with good health worker support have a 28.7 times greater chance of compliance. In contrast, access to health services did not show a significant relationship (p > 0.05). The compliance of tuberculosis patient’s is influenced by education, positive attitude, family support, and attention from health workers. Interventions focused on strengthening patient education and increasing support from health workers are recommended to improve the success of tuberculosis treatment.
Karakteristik serum wajah dari sediaan filtrat rumput laut Eucheuma cottonii dan Ulva lactuca: Characteristics of facial serum from seaweed filtrate of Eucheuma cottonii and Ulva lactuca Nusaibah, Nusaibah; Muhammad, Taufik; Pangestika, Widya; Siregar, Arpan Nasri; Utami, Kamilia Dwi
Jurnal Pengolahan Hasil Perikanan Indonesia Vol. 26 No. 3 (2023): Jurnal Pengolahan Hasil Perikanan Indonesia 26 (3)
Publisher : Department of Aquatic Product Technology IPB University in collaboration with Masyarakat Pengolahan Hasil Perikanan Indonesia (MPHPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17844/jphpi.v26i3.46874

Abstract

Kulit membutuhkan antioksidan untuk menangkal radikal bebas yang di antaranya berasal dari polusi udara dan paparan sinar ultraviolet. Rumput laut Eucheuma cottonii dan Ulva lactuca dikenal memiliki kandungan antioksidan yang cukup tinggi. Produk perawatan kulit salah satunya serum dapat dijadikan alternatif dalam mengurangi permasalahan pada kulit melalui penambahan bahan aktif dari rumput laut. Penelitian ini bertujuan untuk menentukan formulasi terbaik dan pengaruh penambahan E. cottonii dan U. lactuca terhadap karakteristik produk serum wajah melalui parameter uji hedonik, pH, kelembapan, homogenitas, viskositas, dan aktivitas antioksidan. Perlakuan dalam penelitian dibagi menjadi empat, yaitu serum tanpa penambahan filtrat rumput laut (F0), serum dengan penambahan filtrat E. cottonii (F1), serum dengan penambahan filtrat U. lactuca (F2), dan serum kombinasi filtrat E. cottonii dan U. lactuca (F3). Analisis data menggunakan uji Kruskal Wallis dan one way ANOVA. Penambahan filtrat E. cottonii dan U. lactuca dapat memengaruhi nilai antioksidan, hedonik, homogenitas, pH, viskositas, dan kelembapan pada produk serum. Hasil penelitian menunjukkan bahwa formula serum terbaik diperoleh pada perlakuan penambahan filtrat E. cottonii (F1) dengan aktivitas antioksidan (IC50) sebesar 299,29 µg/mL, kelembapan 58,42%, nilai pH 6,25, viskositas 276,71 cP dan paling disukai oleh panelis berdasarkan parameter ketampakan, warna, aroma, tekstur, dan homogenitas.
Relationship Between Nasal Congestion and Learning Concentration in Medical Student Nugroho, Yogi Agustian; Sardjana, Andriana Tjitria Widi Wardani; Sulistyanto, Agung; Yusuf, Iwang; Utami, Kamilia Dwi
Journal of Advanced Multidisciplinary Research Vol 6, No 2 (2025): December 2025
Publisher : Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/jamr.6.2.108-113

Abstract

Allergic Rhinitis is not a fatal disease, but it can affect a person's quality of life and interfere with work, including their ability to learn. One of the most frequently complained of symptoms of allergic rhinitis is a blocked nose. The worldwide prevalence of allergic rhinitis affects between 10%-30% of the population. The aim of this study was to determine the relationship between nasal congestion and learning concentration allergic rhinitis sufferers among FK UNISSULA students, Class of 2022.This research is an observational study with a cross sectional design with the sample criteria being students of FK Unissula Class of 2022 and 2023 who suffer from allergic rhinitis and meet the inclusion and exclusion criteria. The inclusion criteria in this research were students of FK Unissula Class of 2022 and 2023 and were willing to be research subjects. The exclusion criteria in this study were students with anatomical nasal abnormalities and those experiencing chronic rhinosinusitis with or without nasal polyps, deviated septum, adenoid hypertrophy, and neoplasms.There were 50 respondents from Unissula Medical Faculty students who suffered from allergic rhinitis. It was found that 38 (76%) students had a blocked nose and 12 (24%) students did not experience a blocked nose. The research results showed that the majority of students experienced severe nasal congestion and the majority of students had good concentration on their studies. The results of the analysis of the relationship between nasal congestion and learning concentration in allergic rhinitis sufferers using the Spearman test obtained p 0.000 with a correlation coefficient of 0.538.The results of the analysis above showed that there was a significant relationship between nasal congestion and learning concentration in allergic rhinitis sufferers.
Co-Authors Agung Sulistyanto Amaliyah, Laily Rezky Amanda, Qorry Amelia Amelia Anita Soraya Soetoko Fatikhasari, Amalia Nurazima Iwang Yusuf Lusito, Lusito Muhammad, Taufik Nugroho, Bayu M.A Nugroho, Yogi Agustian Nurmalita, Ar-Rahmah Nusaibah Nusaibah Riza, Mohamad Sardjana, Andriana Tjitria Widi Wardani Siregar, Arpan Nasri Suryani Yuliyanti, Suryani Widya Pangestika Yuniarifa, Conita