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All Journal International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Althea Medical Journal Global Medical and Health Communication Indonesian Journal of Cardiology ACI (Acta Cardiologia Indonesiana) Majalah Kedokteran Neurosains Journal of Accounting and Finance Management (JAFM)
Chaerul Achmad
Department Of Cardiology And Vascular Medicine Faculty Of Medicine Universitas Padjadjaran
Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Correlation between Triglyceride/HDL Ratio with Severity of Coronary Artery Lesion in Non-Diabetic Stable Angina Pectoris Patients Pramon Aditya Sudjana; Chaerul Achmad; Achmad Fauzi Yahya; Januar W. Martha; M. Rizki Akbar
ACI (Acta Cardiologia Indonesiana) Vol 4, No 2 (2018)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.40854

Abstract

Background: Triglycerides (TG) as a risk factor for coronary artery disease (CAD) is still a matter of controversy but when used as a single ratio with high density lipoprotein (HDL) the predictive value for CAD is better. The TG/HDL ratio is also associated with the presence of small dense LDL (sdLDL) in the body. SdLDL is a more atherogenic LDL subfraction and has been proven to be associated with CAD progression.Aims: This study aims to find the correlation between the TG/HDL ratio and the degree of coronary lesion severity based on the Gensini score in stable non diabetic angina pectoris patients.Methods: This study was a cross sectional study conducted at Dr. Hasan Sadikin Hospital and Hasna Medika Palimanan Hospital. Subjects were non diabetic stable angina pectoris patients ≥18 years old who underwent elective coronary angiography. Blood collection for TG and HDL examination was performed after coronary angiography. Gensini scoring system was used to assess the severity of coronary lesions. The relationship between the TG/HDL ratio and the Gensini score was analyzed using multiple linear regression tests against confounding variables.Results: This study involved 60 patients with stable angina pectoris with a mean age of 60±8 years. The mean TG/HDL ratio is 2.56 ± 1.04. The average Gensini score was 51 ± 36. The TG/HDL ratio was significantly associated with the Gensini score (R = 0.637; p <0.001). Analysis of confounding variables showed age, hypertension, and metabolic syndrome had a weak correlation with Gensini score (r values of 0.321, 0.270, and 0.333, p <0.05, respectively), while those correlating with TG/HDL ratios were men, hypertension, and metabolic syndrome (r values of 0.290, 0.287, and 0.362, p <0.05, respectively).Conclusion: TG/HDL ratio was significantly positively correlated significantly with the severity of coronary lesions based on Gensini score in non diabetic stable angina pectoris patients.
Correlation between HbA1c Levels with Carotid Intima Media Thickness in Newly Diagnosed Type 2 Diabetes Mellitus Patients Reza Pramayudha; Chaerul Achmad; Erwinanto Erwinanto; Januar W. Martha; M.Rizki Akbar
ACI (Acta Cardiologia Indonesiana) Vol 5, No 2 (2019)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (501.116 KB) | DOI: 10.22146/aci.50218

Abstract

Background: Type 2 diabetes mellitus (T2DM) is the most common chronic disease in the world. Macrovascular complications such as cardiovascular and cerebrovascular diseases can be detected early, one of them by using an ultrasound examination to assess carotid intima-media thickness (CIMT). HbA1c examination had a strong predictive value for the occurrence of T2DM complications. HbA1c levels are associated with CIMT in the non-DM group. In the T2DM group there was an increase in CIMT compared to the non DM group. HbA1c levels can be used as a predictor of the progression of CIMT improvement in the T2DM group, but there is no study on populations with newly diagnosed T2DM.Aims: This study was conducted to find out the correlation between HbA1c in newly diagnosed T2DM and CIMT.Methods: This was a cross-sectional study with correlation analysis carried out on newly diagnosed T2DM in four Primary Health Centers in the city of Bandung who were randomly selected from July to August 2018. HbA1c measurement was carried out at Dr. Hasan Sadikin hospital. The CIMT examination was done according to the Manheim Consensus by a cardiologist. Pearson correlation analysis was performed to assess the relationship between those two variables.Results: This study involved 32 subjects with a median age of 52 (40 - 60) years. The mean value of CIMT was 0.77±0.22 mm, while the median value of HbA1c was 6.7 (5.2- 12.3). Bivariate analysis showed a moderate positive correlation between HbA1c and CIMT in newly diagnosed patients with T2DM. (r= 0.567, p<0.001).Conclusion: There was a significant positive correlation between HbA1c in newly diagnosed T2DM and CIMT.
Faktor Risiko Pneumonia Paska Operasi Bedah Pintas Arteri Koroner Fadhilah, Vita Karima; Achmad, Chaerul; Afrianti, Rien; Santoso, Prayudi
Jurnal Kardiologi Indonesia Vol 45 No 4 (2024): Online First - Indonesian Journal of Cardiology April-June 2021
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1789

Abstract

Background: Postoperative pneumonia (POP) is a common infectious complication of coronary artery bypass grafting (CABG), leading to significant morbidity, mortality, and increased healthcare costs. This study found that the prevalence of POP was nearly double that reported in previous studies, underscoring the urgent need to identify specific risk factors. These findings emphasize the importance of local data in refining preventive strategies and improving clinical outcomes in CABG patients. Material and Methods: This is a retrospective cohort study. The subjects comprised patients who underwent CABG procedures at a single institution between June 2020 and June 2024. A logistic regression analysis model for evaluating the risk of POP was established. Results: This study observed a POP rate of 41.7%, significantly exceeding the 2–24% range reported in previous studies. Key risk factors included elevated creatinine levels, eGFR <60 ml/min/1.73 m², and low early postoperative albumin. POP strongly correlated with prolonged hospitalization, with an odds ratio of 13.043 (95% CI: 6.130–27.751, p < 0.0001), underscoring its substantial impact on patient outcomes. Conclusions: The present study delineates renal impairment and hypoalbuminemia postoperative as pivotal risk factors for POP following CABG. It emphasizes the importance of tailored interventions, structured institutional practices, and continuous research to enhance preventive strategies and patient outcomes.
Non-traditional Lipid Profile and Obstructive Coronary Artery Disease Based On CAD-RADS Score Munita, Fatihatul Firdaus; Kusumawardhani, Nuraini Yasmin; Achmad, Chaerul; Astuti, Astri; Muthiah, Azizah
Jurnal Kardiologi Indonesia Vol 46 No 1 (2025): January - March, 2025
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1810

Abstract

Background: The association between dyslipidemia and coronary artery disease (CAD) is undisputable. Current evidence suggests that, in comparison to conventional lipid parameters, a comprehensive non-traditional lipid profile serves as a more robust predictor of CAD. The evidence regarding the correlation between nontraditional lipid profile and severity of coronary lesions, as measured by the coronary artery disease-reporting and data system (CAD-RADS) score by Coronary Computed Tomography Angiography (CCTA), is still scarce. This study aimed to elaborate on the association between those parameters. Understanding these associations may improve risk stratification and management in CAD patients. Methods: A cross-sectional single-center study was conducted in a large population of patients with suspected CAD. Data were obtained from medical records between January 2020 and February 2024. The CAD-RADS score was stratified into three groups: CAD-RADS 0 (no CAD), CAD-RADS 1-2 (stenosis <50%, classified as non-obstructive CAD), and CAD-RADS ≥3 (stenosis ≥50% in ≥1 coronary segment, classified as obstructive CAD). Logistic regression analysis analyzes the association between patients' lipid profiles and CAD-RADS scores. P-value <0.05 was considered statistically significant. Results: A total of 543 (274 female) patients were included in this study. In the univariate analysis, the LDL/HDL ratio was significantly associated with the severity of CAD based on CAD-RADS scores. The multivariate analysis revealed that the LDL/HDL ratio was the most significant lipid parameter across all models (Adj OR: 9.728, 95% CI: 2.078-45.649, P = 0.004), with the highest adjusted odds ratio observed after adjustments for age, gender, family history, history of hypertension, diabetes mellitus, and chronic kidney disease, and also smoking status. The LDL/HDL ratio cut-off value was 2.82 with a sensitivity of 83.95% and a specificity of 21.05%. Other non-traditional lipid profiles lost their significance in the multivariate models. Conclusions: The LDL/HDL ratio was significantly associated with obstructive CAD, as assessed by the CAD-RADS score, even after adjustment for other cardiovascular risk factors
Mexiletine in the treatment of LQT2, LQT3, and acquired LQTS: a meta-analysis Ihsan, Dhiya; Iqbal, Mohammad; Cool, Charlotte Johanna; Achmad, Chaerul; Pramudyo, Miftah; Prameswari, Hawani Sasmaya; Akbar, Mohammad Rizki
Jurnal Kardiologi Indonesia Vol 46 No 2 (2025): April - June, 2025
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1835

Abstract

Background: High mortality in patients with Long QT Syndrome (LQTS) can be reduced with proper treatment. Gene-specific therapy is crucial, as many treatments are not equally effective across different LQTS types. While mexiletine has been established in the treatment of LQT3, its use in other types of LQT need further evaluation. Methods: A meta-analysis was conducted using systematic electronic searches of PubMed, Embase, and Cochrane Library. We assessed QTc reduction and cardiac events after Mexiletine treatment. Inclusion criteria: any study with no language restriction that diagnoses any type of LQTS, uses mexiletine treatment, and provides QTc comparison before and after treatment. Animal studies were excluded. The NIH Study Quality Assessment Tools and Newcastle-Ottawa Scale were used to evaluate bias. Data were analyzed using Review Manager 5.4 and MedCalc software Results: Nine studies (n=281) were included. Mexiletine reduced QTc by -64ms (mean difference [MD], -64.22; 95% confidence interval [CI] -76.13 to -52.30; p<.001; I2 60%). Sensitivity and subanalyses showed consistent efficacy. In five studies (n=76), the number of patient with high-risk QTc (>500ms) significantly decreased (Risk Ratio [RR], 0.38; 95% CI 0.26-0.55; p<.001). Five studies (n=141) showed a significant reduction in cardiac events (RR, 0.25; 95% CI 0.14-0.44; p<.001). Two studies reported gastrointestinal (GI) problems and vertigo as side effects of mexiletine treatment. Conclusion: Mexiletine significantly reduces QTc and cardiac events in LQT2, LQT3, and aLQT patients. Mexiletine also significantly reduces the number of Long QT patients with high-risk QTc Funding: No external funding was received for this study Registration: CRD420250652574
The Effect of Corporate Governance, Financial Performance, and Financial Slack on Green Banking Kusumawardani, Flavia; Achmad, Chaerul; Nur Hadiyati, Siti
Journal of Accounting and Finance Management Vol. 6 No. 3 (2025): Journal of Accounting and Finance Management (July - August 2025)
Publisher : DINASTI RESEARCH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/jafm.v6i3.2219

Abstract

Bank Indonesia regulations have required the banking industry to implement green banking practices to advance sustainability aspects that beneficial for the environment. Examining the relationship between green banking and corporate governance, financial performance, and financial slack is the focus of this study. Quantitative methods are employed in this study.  With the use of a purposive sampling approach, 80 samples were collected from 21 different banks that were listed on the Indonesia Stock Exchange for the year 2019–2023. Statistical Package for the Social Sciences (SPSS) version 29 was utilized to evaluate the data via multiple linear regression approaches. The findings indicated that simultaneously corporate governance, as represented by the board of directors, board of commissioners, and independent commissioners, significantly influenced green banking. Partially, corporate governance, as represented by the board of commissioners, significantly influences green banking disclosure; nevertheless, the board of directors, independent commissioners, financial performance, and financial slack do not impact green banking disclosure.
Co-Authors - Erwinanto, - - Sugiantoro, - Abdul Hadi Martakusumah Achmad Fauzi Yahya Afrianti, Rien Akbar, Mohammad Rizki Andini Nurkusuma Wardhani Andini Nurkusuma Wardhani, Andini Nurkusuma ASTRI ASTUTI Augustine Purnomowati Augustine Purnomowati Cool, Charlotte Johanna Dini Rostiati, Dini Erwan Martanto Erwan Martanto Erwinanto Erwinanto Fadhilah, Vita Karima Fajar Ashari, Fajar Fatihatul Firdaus Munita, Fatihatul Firdaus Ferdy Sanjaya Giky Karwiky Ihsan, Dhiya Januar W. Martha Januar W. Martha Januar Wibawa Martha Jungjunan, Ridho Kusumawardani, Flavia Kusumawardhani, Nuraini Yasmin M. Rizki Akbar M.Rizki Akbar Mega Febrianora Muhammad Munawar Muhammad Rizki Akbar, Muhammad Rizki Muthiah, Azizah Nur Hadiyati, Siti Pintoko Tedjokusumo, Pintoko Prameswari, Hawani Sasmaya Pramon Aditya Sudjana Pramudyo, Miftah Prayudi Santoso R. Reni Farenia Soedjana Ningrat Reza Pramayudha Sunaryo B. Sastradimaja Sunaryo B. Sastradimaja, Sunaryo B. Syarief Hidayat Toni Mustahsani Aprami Toni Mustahsani Aprami, Toni Mustahsani Yahya­, Achmad Fauzi Yoga Yuniadi