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Manajemen Pterigium Marcella, Maria
Cermin Dunia Kedokteran Vol 46, No 1 (2019): CME - Continuing Medical Education
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (699.317 KB) | DOI: 10.55175/cdk.v46i1.532

Abstract

Pterigium adalah pertumbuhan fibrovaskular non maligna konjungtiva yang biasanya mencapai kornea dan berbentuk segitiga terdiri dari degenerasi fibroelastis dengan dominasi proliferasi fibrotik. Faktor risiko pterigium antara lain terutama paparan sinar ultraviolet, paparan debu atau iritan, kekeringan mata, faktor genetik. Untuk prevensi, dapat digunakan kacamata yang memblok sinar ultraviolet. Terapi surgikal eksisi dengan risiko komplikasi rekurensi pertumbuhan fibrovaskular dari limbus ke tengah kornea. Teknik eksisi antara lain bare sclera, conjunctival autograft technique, amniotic membrane grafting. Terapi tambahan untuk mengurangi rekurensi, dapat menggunakan mitomycin-C, radiasi beta, dan anti-VEGF (Vascular Endothelial Growth Factor).Pterygium is a triangular shaped non malignant fibrovascular growth of conjunctiva, usually spread to cornea and consist of fibroelastic degeneration with dominant fibrosis. The risk factors are mainly exposure of ultraviolet, exposure to irritants or dust, dry ocular surface, also genetic factors. Proper protective eyewear (sunglasses) is recommended for prevention. Surgical excision has a risk of recurrent fibrovascular growth from limbus to central of cornea. Excision techniques are bare sclera, conjunctival autograft technique, amniotic membrane grafting. Adjunctive therapies to decrease recurrency are mitomycin C (MMC), beta irradiation therapy and also anti-VEGF (Vascular Endothelial Growth Factor). 
Dragon Fruit Peel Extract and Encapsulated Catfish Oil Formulation in Gummy Candy with Potential In Vitro Antihyperglycemia Properties Aurelia, Jovita; Trifena, Felicia; Levi, Kelvin; Marcella, Maria; Septiyani; Agustinah, Widya
Journal Akademik Universitas Swiss German Vol. 3 No. 2 (Feb 2022)
Publisher : Swiss German University & Perhimpunan Penggiat Pangan Fungsional dan Nutrasetikal Indonesia (P3FNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33555/jffn.v3i2.87

Abstract

Red dragon (Hylocereus polyrhizus) fruit peel as household waste was still underutilized although it was high in bioactive compounds with antioxidant and antidiabetic properties. The oil extract of freshwater fish, such as catfish (Pangasius sp.) was high in monounsaturated fatty acids with reported antihyperglycemia properties. The objectives of this study were to encapsulate catfish oil extract, determine the most liked formulation of gummy candy with dragon fruit peel extract and encapsulated fish oil beads content, and analyze the proximate content and in vitro α-amylase inhibition activity of the most liked gummy candy formulation. The methods consisted of dragon fruit peel extraction, encapsulation of catfish oil extract using sodium alginate, gummy candy formulation, sensory evaluation, and analysis of color, proximate, and α-amylase inhibition activity. Twenty five percent w/w of the gummy candy ingredients were composed of the extracts and encapsulation beads at 1:1, 1:3, and 3:1 weight ratios. Encapsulation of the fish oil could mask the fishy odor in the gummy candy. All formulation could be molded into gummy candy perfectly and showed chewy texture. The addition of dragon fruit peel extract could increase the yellowness value, while the fish oil beads decreased the lightness value of the candy. The most liked gummy candy formulation was F3 (ratio 3:1). It was composed of 54.47% water, 1.59% db ash, 5.77% db fat, 1.82% db protein, 36.36% db carbohydrates and showed 46.49% α-amylase inhibition activity.
Potensi bakteri termofilik asal kawah Domas Tangkuban Perahu sebagai agen biodekolorisasi zat warna Naphthol Asbo-Blue B Marcella, Maria; Muharni, Muharni
Sriwijaya Bioscientia Vol 5 No 2 (2024)
Publisher : Biology Department, Faculty of Mathematics and Natural Sciences, Sriwijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24233/sribios.5.2.2024.484

Abstract

Industri batik memiliki peran penting dalam perekonomian Indonesia, namun banyaknya jumlah industri batik di Indonesia tidak diimbangi dengan pengolahan limbah cair dengan baik dan benar. Salah satu komponen air limbah batik adalah pewarna sintetis Naphthol ASBO-Blue B. Pengolahan secara biologis dengan menggunakan bakteri dapat mengurangi dampak tersebut, dan perlu dilakukan eksplorasi lebih lanjut terhadap bakteri termofilik. Penelitian ini bertujuan untuk mendapatkan isolat bakteri termofilik yang berpotensi mendekolorisasi zat warna Naphthol ASBO-Blue B., serta mengetahui jenis isolat yang memiliki kemampuan dekolorisasi lebih dari 50% melalui analisis gen 16S rRNA. Enam isolat bakteri dari sumber air panas Tangkuban Perahu mampu mendekolorisasi Naphthol ASBO-Blue B. pada konsentrasi 100 ppm selama 7 hari dengan persentase kemampuan biodekolorisasi terbesar dimiliki oleh isolat DS2D yaitu 53,03 ± 0,28%. Isolat DS2D memiliki bentuk streptobasil, bersifat gram positif, dan menghasilkan endospora. Sekuen isolat DS2D menunjukkan kemiripan yang tinggi dengan Bacillus tropicus strain MCCC 1A01406, yaitu sebesar 97,90%.