Christopher Yo, Edward
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Upaya Menurunkan Angka Kematian Ibu akibat Perdarahan Pasca Persalinan di Indonesia melalui Inovasi Sistem Pelayanan Kesehatan Remifta Putra, Muhammad Alifian; Christopher Yo, Edward; Phowira, Jason; Dewi Anggraeni, Tricia
Cermin Dunia Kedokteran Vol 47, No 12 (2020): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.98 KB) | DOI: 10.55175/cdk.v47i12.1250

Abstract

Perdarahan pasca-persalinan (PPP) adalah komplikasi persalinan yang menyebabkan 35% seluruh kematian ibu di dunia. Meskipun PPP mulai jarang ditemui di negara maju, kondisi ini masih merupakan salah satu penyebab utama kematian ibu di negara berkembang seperti Indonesia. Hal ini antara lain akibat infastruktur kesehatan yang kurang optimal, sehingga terlambat mengidentifikasi faktor risiko PPP, merujuk, serta memberikan intervensi tepat waktu. Kajian pustaka ini mengamati adanya hubungan signifikan antara penurunan kematian ibu akibat PPP dan implementasi sistem peringatan dini obstetri, manajemen efektif, dan optimalisasi alur rujukan. Namun, karena tiap wilayah memiliki aspek sosioekonomis dan geografis yang berbeda, studi lanjutan diperlukan untuk menentukan pendekatan yang tepat bagi masing-masing wilayah di Indonesia.Postpartum hemorrhage (PPH) is a life-threatening condition that contributes to 35% of all maternal deaths worldwide. Although the risk of PPH has greatly declined in developed countries, it remains a leading cause of maternal mortality in developing countries like Indonesia. This issue could mainly be attributed to poor healthcare system and infrastructure leading to delay in identifying risk factors, referring mothers-at-risk to health centers, and appropriate intervention. We observed a notable relationship between decrease in maternal deaths due to PPH and the implementation of early warning system, effective PPH management, and optimization of referral system. These healthcare innovations showed promising potential in reducing the burden of PPH. However, since there is no single health policy that can be universally implemented, further research is needed to decide the best approach for each area depending on individual, socio-economic and geographic aspects.
Integrasi Misoprostol dalam Daftar Obat Esensial Nasional sebagai Alternatif Penanganan Perdarahan Pasca-Persalinan di Wilayah Pedesaan di Indonesia Christopher Yo, Edward; Remifta Putra, Muhammad Alifian; Phowira, Jason
Cermin Dunia Kedokteran Vol 47, No 10 (2020): Optalmologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.528 KB) | DOI: 10.55175/cdk.v47i10.1091

Abstract

Di Indonesia, angka kematian ibu akibat perdarahan pasca-persalinan (PPP) masih tinggi, terutama di wilayah pedesaan dengan akses terhadap oksitosin sebagai obat lini utama masih sangat terbatas. Misoprostol berpotensi menjadi alternatif oksitosin untuk penanganan PPP di wilayah pedesaan. Telaah literatur manfaat misoprostol menggunakan search engine Google Scholar, PubMed, dan NCBI, dengan kata kunci “misoprostol”, “perdarahan pasca-persalinan”, “wilayah dengan sumber daya rendah”, farmakokinetika”, “farmakodinamika”, dan “Indonesia”. Ditinjau dari aspek Cmax, Tmax, dan AUC, jalur sublingual diduga paling efektif. Penelitian lebih lanjut diperlukan untuk memastikan rute pemberian serta dosis misoprostol yang paling efektif untuk penanganan kasus PPP. Namun, misoprostol belum terdaftar di Daftar Obat Esensial Nasional (DOEN). Ditetapkannya misoprostol dalam DOEN akan memastikan ketersediaannya di fasilitas kesehatan di Indonesia, sehingga manajemen PPP di wilayah pedesaan dapat lebih efektif.In Indonesia, postpartum hemorrhage (PPH) continues to be a leading cause of maternal death, especially in rural areas with limited access to oxytocin as the first-line therapy in PPH management. Misoprostol can become an alternative drug for PPH management in rural areas. Literature search was conducted using Google Scholar, PubMed, and NCBI, with keywords including “misoprostol”, “perdarahan pasca persalinan”, “wilayah dengan sumber daya rendah”, “farmakokinetika”, “farmakodinamika”, and “Indonesia”. Evaluation of Cmax, Tmax, and AUC showed that the most effective route of delivery for misoprostol is by sublingual administration. Further research is needed to confirm the most effective delivery route as well as optimal misoprostol dosage for PPH management. However, misoprostol has not been enlisted in Daftar Obat Esensial Nasional (DOEN). Inclusion of misoprostol in DOEN will help ensure its availability in health facilities across Indonesia, towards a more effective management for PPH in rural areas.
Current Trends in Contraceptive Use and Fertility Concerns Among Women of Reproductive Age in Indonesia Muharam Natadisastra, Raden; Christopher Yo, Edward; Nurdya Irzanti, Alisha; Sumapraja, Kanadi; Kemal Harzif, Achmad; Pratama, Gita; Maidarti, Mila; Hari Kurniawan, Riyan; Wiweko, Budi; Hestiantoro, Andon
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 1 January 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i1.2508

Abstract

Abstract Background Family planning remains a key intervention in reducing maternal mortality and creating prosperous families. Assessing the unmet need for family planning allows insight into the progress of family planning programs. On the other hand, there has been much less attention given to the declining fertility rate in Indonesia. To address both the unmet need and declining fertility rate in Indonesia, this study aimed to investigate the most recent trends in contraceptive use in Indonesia as well as evaluate fertility concerns and access to reproductive healthcare service. Methods Women of reproductive age in Indonesia were asked to fill in an online questionnaire. They were asked about sociodemographic characteristics, marital status, pregnancy history, perception towards fertility, and access to healthcare service and information. Descriptive statistics and independent t-test were performed. Results Of 370 women, more than half (57.8%) had used some form of contraception. The most frequently used contraceptive method was natural family planning (30.3%), followed by condom (20%). Women with no prior sexual history, had never been pregnant before, and had not been married cared more about having a child in the future. Internet and social media represented the most popular information source for family planning. Conclusions Many Indonesian women still prefer traditional contraceptive methods over the more effective modern contraceptive methods. Numerous socio-cultural factors are likely to influence the behaviour of reproductive-age women regarding contraceptive use and childbearing in the future. More effort should be put into raising awareness about modern contraceptive methods and addressing fertility concerns. Keywords: contraception; fertility; family planning; awareness; reproduction