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COST MINIMIZATION ANALYSIS OF ANTIHYPERTENSIVE DRUG USE IN CHRONIC KIDNEY DISEASE PATIENTS UNDERGOING HEMODIALYSIS Utami, Indah Kurnia; Rakanita, Yasinta; Dewi, Niluh Puspita
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 1 (2025)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i1.1655

Abstract

Hypertension is the primary cause of Chronic Kidney Disease (CKD), as it damages blood vessels in the kidneys. The most commonly used management for hypertension as monotherapy includes Calcium Channel Blockers (CCB) such as Amlodipine and Angiotensin Receptor Blockers (ARB) such as candesartan. Patients with CKD undergoing hemodialysis depend on dialysis machines, which impacts their economic burden. Therefore, a cost analysis review of drugs with the same therapeutic goals is necessary. This was a non-experimental study with a descriptive design. Data were collected through retrospective purposive sampling from January to December 2023 using medical records and payment data for inpatient treatments with hemodialysis that met the inclusion criteria. Direct medical costs included antihypertensive, other medication, service and facility fees, and medical support costs. Of the 100 samples that met the inclusion criteria from January to December 2023, amlodipine was the most commonly used antihypertensive (56%), followed by candesartan (38%). The average direct medical costs were IDR 184.350 for Amlodipine and IDR 561,339 for candesartan. The patient characteristics by gender showed a higher percentage of males (52%) than of females (48%). By age, the majority were in the late adult group (67%), whereas the elderly accounted for (33%). The Amlodipine group achieved more significant cost minimization than the candesartan group. Future studies should examine the potential of amlodipine in reducing the economic burden of limited resources.  Keywords: antihypertensive, CMA, CKD
COST MINIMIZATION ANALYSIS OF ANTIHYPERTENSIVE DRUG USE IN CHRONIC KIDNEY DISEASE PATIENTS UNDERGOING HEMODIALYSIS Utami, Indah Kurnia; Rakanita, Yasinta; Dewi, Niluh Puspita
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 1 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i1.1655

Abstract

Hypertension is the primary cause of Chronic Kidney Disease (CKD), as it damages blood vessels in the kidneys. The most commonly used management for hypertension as monotherapy includes Calcium Channel Blockers (CCB) such as Amlodipine and Angiotensin Receptor Blockers (ARB) such as candesartan. Patients with CKD undergoing hemodialysis depend on dialysis machines, which impacts their economic burden. Therefore, a cost analysis review of drugs with the same therapeutic goals is necessary. This was a non-experimental study with a descriptive design. Data were collected through retrospective purposive sampling from January to December 2023 using medical records and payment data for inpatient treatments with hemodialysis that met the inclusion criteria. Direct medical costs included antihypertensive, other medication, service and facility fees, and medical support costs. Of the 100 samples that met the inclusion criteria from January to December 2023, amlodipine was the most commonly used antihypertensive (56%), followed by candesartan (38%). The average direct medical costs were IDR 184.350 for Amlodipine and IDR 561,339 for candesartan. The patient characteristics by gender showed a higher percentage of males (52%) than of females (48%). By age, the majority were in the late adult group (67%), whereas the elderly accounted for (33%). The Amlodipine group achieved more significant cost minimization than the candesartan group. Future studies should examine the potential of amlodipine in reducing the economic burden of limited resources.  Keywords: antihypertensive, CMA, CKD
Edukasi Pemanfaatan Seledri (Apium graveolens) Bagi Nyeri Hiperurisemia Warga Desa Sejahtera, Kecamatan Palolo, Sulawesi Tengah Rakanita, Yasinta; Anggi, Viani; Tudaan, Leligrafela; Novina, Patricia; Wahyu Handayani, Tien
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 5 No. 2 (2024): Jurnal Pengabdian kepada Masyarakat Nusantara (JPkMN)
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55338/jpkmn.v5i2.3389

Abstract

Kekambuhan yang berulang dari rasa nyeri akibat keluhan hiperurisemia banyak diderita oleh warga Desa Sejahtera, inilah yang menjadi alasan utama dilakukannya kegiatan pengabdian ini. Para kader Puskesmas dan ibu-ibu PKK yang menjadi target utama dari tujuan kegiatan pengabdian yang memberikan peningkatan pengetahuan, keterampilan, dan sikap peduli ibu memanfaatkan seledri untuk atasi nyeri hiperurisemia. Sosok ibu dipilih ini karena seorang ibu umumnya memainkan peran utama sebagai kunci dari pencapaian kemandirian kesehatan keluarga di Desa Sejahtera, Kecamatan Palolo, Kabupaten Sigi, Sulawesi Tengah. Metode pendekatan yang digunakan berupa ceramah, pemeriksaan kadar asam urat, dan praktek pengolahan tanaman seledri sebagai bahan utamanya. Hasil dari kegiatan pengabdian diperoleh sejumlah 81 peserta yang hadir mengalami 70% peningkatan pengetahuan tentang nyeri hiperurisemia; 50% keterampilan mengolah tanaman seledri untuk nyeri hiperurisemia dengan takaran/dosis yang tepat; dan 70% sikap lebih peduli terhadap pemilihan dan pembersihan seledri sebagai bahan herbal yang tepat, aman, dan ekonomis. Pentingnya hasil pengabdian ini telah membawa pada simpulan warga yang menjadi sasaran kegiatan bahwa ini yang pertama kali mereka menerima pengetahuan, keterampilan, dan bimbingan sikap dalam mengatasi kekambuhan nyeri hiperurisemia Sehingga ada perubahan peningkatan yang nyata, pada pengetahuan hiperurisemia dan pemanfaatan tanaman seledri dengan takaran yang tepat, untuk mengatasi nyeri hiperurisemia.
SOSIALISASI DAN EDUKASI DAGUSIBU OBAT DENGAN BENAR PADA MASYARAKAT KELURAHAN TATURA UTARA, PALU SELATAN Dewi, Niluh Puspita; Wirawan, Wayan; Rakanita, Yasinta; Polontalo, Nani Astria; Insani, Fadillah
Jurnal Abdi Insani Vol 12 No 10 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i10.2873

Abstract

Various health problems, particularly those related to drugs, persist in the community. This can be caused by a lack of public understanding of the proper use and handling of drugs. The DAGUSIBU program is one method for proper drug management. The goal of DAGUSIBU outreach is to increase public understanding of drugs and how to manage and monitor their proper use. The methods used include public education through counseling and practical training. The effectiveness of the outreach was tested using pre- and post-tests, as well as a community satisfaction questionnaire. The results showed an increase in public knowledge and understanding after the DAGUSIBU outreach and education activities. Overall, the average increase in knowledge and understanding of DAGUSIBU among participants was 84%. This can help the government provide better health services. By improving participants' understanding of proper drug management, this outreach is expected to enable them to utilize the knowledge they gain within their families and communities.