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All Journal Indonesian Journal of Urology
Sabilal Alif
Departemen/SMF Urologi, FK Universitas Airlangga/RSUD Dr. Soetomo. Jl. Prof. Dr. Moestopo 6-8, Surabaya 60286
Health Professions Medicine & Pharmacology Public Health

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PENGARUH ISKEMIA TERHADAP PENINGKATAN KOLAGEN PADA KORPUS KAVERNOSUM Alif, Sabilal
Indonesian Journal of Urology Vol 15 No 1 (2008)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v15i1.363

Abstract

Objective: To demonstrate that ischemia causes elevation of collagen in cavernous body. Material & Method: Sample used in this study were male adult rabbits (Oryctalagus Cuniculus) 6 – 9 months of age. Partial ligation of both common iliac arteries was performed in this study to induce cavernous body ischemia. Results: Collagen mean for 7 x 24 hours ligation group (group B) increased to 113,83/200 compared to the collagen mean for the 2 x 24 hours ligation group (group A) which was 91,08/200 and collagen mean for control group (group C) which was 86,90/200. There was collagen elevation on treatment group which caused by ligation (Anova, F value= 12,110 and p=0,0001). Conclusion: Ischemia may elevate collagen in cavernous body. 
Co-Authors A.A. Ketut Agung Cahyawan W Anton Hermawan As'ari, Musa Benny Kristyantoro Doddy M Soebadi Doddy Musbadianto Soebadi Eddy Sunarno, Eddy Endi Prilansa Mahadi Heru Nurdianto I Wayan Yudiana Kartuti Debora, Kartuti Marzuki Yusuf, Marzuki Purwati Purwati Sunaryo Hardjowijoto Tarmono Djojodimedjo Tri Wulanhandarini wahjoe djatisoesanto Wibisono Wibisono Widodo J P Widodo Pudjirahardjo Willy Sandhika Yudi Y Ambeng