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All Journal Jurnal Biologi Tropis Pharmademica: Jurnal Kefarmasian dan Gizi Jurnal Teknik Sipil Institut Teknologi Padang
Pratiwi, Yani
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Engineering Immunology & microbiology Public Health Transportation

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Formulation and Evaluation of Red Betel Leaf (Piper crocatum L) Ethanol Extract 96% in Anti-Acne Cream Pratiwi, Yani; Azis, Asyari Al Hutama; Dilla, Nurfarah
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9570

Abstract

Acne (Acne vulgaris) is a common skin problem experienced, especially by teenagers and young adults, which can lower self-esteem. One causes is bacteria Propionibacterium acnes and Staphylococcus epidermidis. Red betel leaves (Piper crocatum L) are known to contain active compounds such as flavonoid, tannins, alkaloid, and essential oil that effective as antibacterial and anti-inflammatory agents. The aim of this study is to formulate and evaluate a topical cream containing a 96% ethanol extract of red betel leaves (Piper crocatum L.) as an anti-acne preparation. This study employed a laboratory experimental approach, formulating an oil-in-water (O/W) type cream by varying the concentrations of the emulsifiers stearic acid and triethanolamine (TEA). The physical properties of the cream were assessed through organoleptic evaluation, homogeneity testing, pH measurement, spreadability, adhesion, viscosity, cream type identification, and mechanical stability testing. The results that formula IV with an extract concentration of 12.5%, stearic acid 17%, and TEA 3.5% produces the most optimal results, with stable physical characteristics, homogeneous, and meeting topical cosmetic standards. Thus, 96% ethanol extract cream of red betel leaf has potential to be used as alternative treatment for acne based on natural ingredients.
Penilaian Kelayakan Struktur Gedung Kuliah Sekolah Tinggi Teknologi Payakumbuh Masdar, Astuti; Pratiwi, Yani; Masdar, Anita Dewi; Noviarti
Jurnal Teknik Sipil Institut Teknologi Padang Vol 11 No 2 (2024): Jurnal Teknik Sipil institut Teknologi Padang
Publisher : ITP Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21063/jts.2024.V1102.0138-143

Abstract

Asesmen dilakukan sebelum renovasi dilaksanakan terhadap salah satu bangunan di Sekolah Tinggi Teknologi Payakumbuh yang berfungsi sebagai gedung perkuliahan. Asesmen sangat penting dilakukan mengingat bangunan merupakan gedung Sekolah Dasar (SD) hibah dari Pemerintahan Kota Payakumbuh, yang telah dibangun sejak tahun 1984. Metode yang dilakukan dalam penelitian adalah metode kuantitatif melalui asesmen secara visual dan teknikal serta analisis kapasitas penampang pada kondisi eksisting. Berdasarkan hasil asesmen secara visual diketahui kerusakan pada kolom berupa void, spalling dan korosi pada tulangan kolom dan pelat di bagian belakang bangunan serta retak halus pada dinding.  Sementara itu dari hasil asesmen secara teknikal dengan Hammer Test diketahui kuat tekan rata-rata untuk komponen struktur kolom adalah fc’ = 18,7 MPa, balok dan pelat adalah fc’ = 16,7 MPa. Hasil analisis kapasitas bangunan menunjukkan bahwa kondisi eksisting mempunyai kapasitas yang melebihi beban ulitimit sehingga renovasi dengan penggantian granit pada lantai dan bahan yang cukup berat untuk keperluan arsitektur masih dapat dilaksanakan.
Antifungal Effectiveness Test of Gleichenia linearis Burm. (Farm) Leaf Extract on Candida albicans Fungi Azis, Asyari Al Hutama; Pratiwi, Yani; Nurfirawati, Nurfirawati
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10781

Abstract

The fern leaf (Gleichenia linearis Burm.) is a species of fern known to have potential as an agent that inhibits fungal growth. This study aims to test the antifungal effectiveness of fern leaf extract against the growth of Candida albicans and determine the most effective concentration. The extract was obtained through 70% ethanol maceration from 500 g of dried leaves, then formulated in concentrations of 5%, 10%, and 20%. Disc diffusion tests were carried out on SDA media, with 10 μg ketoconazole as a positive control and 70% ethanol as a negative control. The results showed an average inhibition zone of 4.66 mm (5%), 6.91 mm (10%), and 10.83 mm (20%), while the positive control was 18.54 mm and the negative control showed no inhibition. The Kruskal-Wallis test (Sig.) <0.05 was used as a reference resulting in a p value = 0.009, indicating a significant difference between groups. The results of phytochemical screening showed the presence of alkaloids, flavonoids, saponins, tannins, phenolics, and terpenoids. In conclusion, fern leaf extract is effective in inhibiting the growth of Candida albicans, with a concentration of 20% being the most effective.
Standardisasi Simplisia dan Ekstrak Daun Jambu Mete (Anacardium occidentale L.) dari Kabupaten Gowa Sulawesi Selatan Azis, Asyari Al Hutama; Pratiwi, Yani; Putri, Irva Maulidiyah
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 5 No 2 (2026): Oktober - Maret
Publisher : LPPM-KI - POLTEKKES PIM (Formerly AKAFARMA-AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54445/pharmademica.v5i2.118

Abstract

Cashew leaves (Anacardium occidentale L.) contain secondary metabolite compounds such as flavonoids, tannins, polyphenols, alkaloids, saponins, and phenolics, which exhibit pharmacological activities, including antioxidant and antibacterial properties. Traditionally, cashew leaves are used by the people of Gowa Regency to treat diabetes mellitus, oral inflammation, burns, muscle aches, and skin infections such as acne and boils. This study aims to evaluate the quality of cashew leaf raw materials from Gowa Regency based on specific parameters, namely water-soluble and ethanol-soluble extract content in the simplicia. Additionally, nonspecific parameters were evaluated, including drying loss, total ash content, and acid-insoluble ash content in the simplicia, as well as water content, total ash content, and acid-insoluble ash content in the extract, according to the Indonesian Herbal Pharmacopoeia Edition II (2017). Extraction was performed using the maceration method with 70% ethanol, yielding 21.2%. The results showed that the simplicia contained 13.46% water-soluble extract, 18.23% ethanol-soluble extract, 9.93% drying loss, 3.03% total ash, and 0.71% acid-insoluble ash. Meanwhile, the extract showed a water content of 18.26%, total ash of 0.89%, and acid-insoluble ash of 0.39%. Both the simplicia and extract of cashew leaves from Gowa Regency met the quality requirements of the Indonesian Herbal Pharmacopoeia Edition II (2017) and were categorized as high quality.
Co-Authors astuti masdar, astuti Azis, Asyari Al Hutama Dilla, Nurfarah Khamdanah, Khamdanah M. Yogi Riyantama Isjoni Masdar, Anita Dewi Nada, Luthfia Qothrun Nurfirawati, Nurfirawati Putri, Irva Maulidiyah Sabrina, Fadya Putri