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All Journal Journal of Applied Health Management and Technology Media Kesehatan Politeknik Kesehatan Makassar Jurnal Media Analis Kesehatan
Askar, M
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Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Aktivitas Antioksidan Dari Tiga Fraksi Pelarut Ekstrak Daun Dandang Gendis (EDDG) Artati, Artati; Widarti, Widarti; Ali Hasan, Zulfikar; Askar, M
Jurnal Media Analis Kesehatan Vol 15 No 2 (2024): JURNAL MEDIA ANALIS KESEHATAN
Publisher : Potekkes Kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/jmak.v15i2.1159

Abstract

Ekstrak daun Dandang Gendis (EDDG) memiliki potensi sebagai agen antioksidan dan antimikroba yang dapat digunakan dalam pengobatan tradisional dan modern. Penelitian ini bertujuan untuk mengeksplorasi manfaat kesehatan dari ekstrak daun ekstrak daun dandang gendis (Clinacanthus nutans L.) serta biokomponen aktif yang terkandung di dalamnya. Jenis penelitian ini merupakan penelitian eksperimental dengan pendekatan kuantitatif yang melibatkan analisis laboratorium. Sampel yang digunakan dalam penelitian ini adalah daun ekstrak daun dandang gendis (Clinacanthus nutans L.) dengan berbagai pelarut, yaitu n-heksan, etil asetat dan etanol. Uji aktivitas antioksidan dilakukan dengan menggunakan metode spektrofotometri UV-Vis menggunakan beberapa pereaksi yang berfungsi sebagai antioksidan diantaranya 2,2-diphenyl-1- picrylhydrazyl (DPPH) dan besarnya aktivitas antioksidan ditandai dengan nilai IC50. Aktivitas antioksidan terhadap radikal DPPH dianalisis menggunakan spektrofotometer visibel pada panjang gelombang 517 nm. Kemampuan aktivitas antioksidan ekstrak dibandingkan dengan asam askorbat. Aktivitas antioksidan (IC50) berdasarkan tiga jenis pelarut yang digunakan untuk mengekstrak yaitu n-heksan, etil asetat, dan etanol masing-masing adalah 1658 µg/ml, 160 µg/ml, dan 2471 µg/ml. Hasil penelitian menunjukkan bahwa ekstrak daun EDDG memiliki aktivitas antioksidan yang signifikan dan dapat menghambat pertumbuhan bakteri patogen. Disarankan untuk melakukan penelitian lebih lanjut mengenai isolasi komponen bioaktif dan uji klinis untuk memancarkan potensi terapeutik dari ekstrak ini.
LITERATURE STUDY OF THE RELATIONSHIP OF KNOWLEDGE AND DISEASE PERCEPTION OF MELLITUS DIABETES WITH SELF-CARING BEHAVIORS OF DIABETES MELLITUS PATIENTS Mutmainah, Ainun; Dalle, Ambo; Askar, M
Journal of Applied Health Management and Technology Vol. 3 No. 2 (2021): April 2021
Publisher : Postgraduate Program , Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jahmt.v1i2.6813

Abstract

Diabetes Mellitus is a chronic disease that requires self-care in a long or long term so that patients can perform self-care independently to prevent complications from Diabetes Mellitus. Self-care behavior aims to assess and classify the extent to which Diabetes Mellitus sufferers perform self-care in order to improve their welfare and quality of life. This study aims to determine the relationship between knowledge and pain perception about Diabetes Mellitus with the self-care behavior of Diabetes Mellitus sufferers. This research is a literature study that summarizes some of the relevant literature collected using Google Scholar published in 2015-2020. The search results showed 46 identified journals and 7 journals that met the inclusion criteria. The results showed that there was a significant relationship between knowledge of Diabetes Mellitus and the self-care behavior of Diabetes Mellitus patients and there was a significant relationship between the perception of pain about diabetes mellitus and the self-care behavior of diabetes mellitus patients.
Gender-Specific Determinants of High Cholesterol: A Cross-Sectional Study Among Health Institution Employees in Makassar, Indonesia Hartono, Rudy; Rusli, Rusli; Fajriah, Siti Nurul; Andini, Mira; Amir, Aswita; Askar, M
Media Kesehatan Politeknik Kesehatan Makassar Vol 20 No 2 (2025): Media Kesehatan
Publisher : Direktorat Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/medkes.v20i2.1949

Abstract

High cholesterol or dyslipidemia is one of the main risk factors for cardiovascular disease (CVD), including coronary heart disease, stroke, and peripheral artery disease. The World Health Organization (WHO) estimates that more than 39% of adults worldwide have total cholesterol levels above safe limits, with more than 4.4 million deaths each year directly related to increased LDL cholesterol levels and decreased HDL. Global trends show a significant increase in the prevalence of dyslipidemia in low- and middle-income countries, particularly in Southeast Asia, driven by changes in diet, urbanization, and decreased physical activity. At the national level, Basic Health Research (Riskesdas) and the Indonesian Nutrition Status Study (SSGI) report show that the prevalence of high cholesterol in Indonesia has continued to increase over the past decade. This study analyzed factors affecting high cholesterol using logistic regression in groups of women and men. The variables tested included blood pressure, body weight, and fasting blood sugar. Using data from 276 employees of a public health polytechnic in Makassar (January–June 2025), separate logistic regression models for women and men revealed that blood pressure was a significant predictor in both groups (ORwomen = 6.48, ORmen = 7.04), while fasting blood sugar was significant only in women (OR = 5.26). The results show that blood pressure is a significant predictor in both groups, while fasting blood sugar is significant only in women. The model explained 50.7% of variance in women versus 39.0% in men. The prediction model shows higher accuracy in women. These findings have important implications for gender-based dyslipidemia prevention efforts.
Co-Authors Ali Hasan, Zulfikar Ambo Dalle Andini, Mira Artati, Artati Aswita Amir Fajriah, Siti Nurul Hartono, Rudy Mutmainah, Ainun R. Rusli WIDARTI WIDARTI