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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Pengabdian Masyarakat Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pharmaceutical Sciences and Research (PSR)
Charisma, Shintia Lintang
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Humanities Education Engineering Medicine & Pharmacology Public Health Social Sciences

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The Potential Roles of Jamu for COVID-19: A Learn from the Traditional Chinese Medicine Hartanti, Dwi; Dhiani, Binar Asrining; Charisma, Shintia Lintang; Wahyuningrum, Retno
Pharmaceutical Sciences and Research Vol. 7, No. 4
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

As the pandemic of the coronavirus disease 2019 (COVID-19) continues while there is no drug and vaccine available, every effort to discover one should be considered. This review aimed to discuss the potential use of jamu, the Indonesian traditional herbal medicine, to deal with COVID-19 by following those of more-established traditional Chinese medicine (TCM). The online literature search using the PubMed database, as well as the circulars from the Indonesian Ministry of Health, were carried out to collect data up to June 07, 2020. The use of TCM for the treatment and prevention of COVID-19 has been officiated in the Chinese National Clinical Guideline on COVID-19 Associated Pneumonia, with shen-fu-tang + su-he-xiang pill and xiang-sha-liu-junzi- tang as the most frequently suggested formulae to treat severe and recovery stages of COVID-19, respectively. In Indonesia, the highly promoted product for the prevention of this disease is likely the adaptation of a TCM formula, while the use of some other formulae, which mainly containing Zingiberaceae, is suggested by the Government for the said purpose. The rationalization of the use of medicinal plants and suggested polyherbal formulae, based on their available pharmacological activity and the bioactive compounds, is also discussed in this review. The use of jamu for COVID-19, however, needs to be carefully considered for the limited scientific data available to support it.
Edukasi Penyimpanan dan Pemusnahan Obat Terhadap Anggota Dawis 4 Desa Sidaboa, Banyumas Hariyanti, Hariyanti; Charisma, Shintia Lintang
Jurnal Pengabdian Masyarakat Indonesia Vol 4 No 5 (2024): JPMI - Oktober 2024
Publisher : CV Infinite Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52436/1.jpmi.2846

Abstract

Latar belakang: Pengetahuan masyarakat terhadap cara penyimpanan dan pemusnahan obat sangat rendah. Hal ini mengakibatkan ketidakstabilan obat sehingga berdampak pada penurunan khasiat dan keamanan. Tujuan: Meningkatkan pengetahuan masyarakat terhadap cara penyimpanan dan pemusnahan obat pada anggota Dawis 4 Desa Sidaboa, Patikraja, Banyumas. Metode: Edukasi dilakukan menggunakan metode penyuluhan, tutorial dan praktik cara penyimpanan dan pemusnahan obat meliputi sediaan solid, semisolid dan liquid. Evaluasi keberhasilan proses edukasi diukur menggunakan pretest dan postest (kuisioner). Kuisioner disusun sebanyak 100 pernyataan (50%: penyimpanan dan 50%: pemusnahan obat). Hasil: Data pretest menunjukan bahwa pengetahuan masyarakat tentang penyimpanan obat sangat rendah (jawaban benar sediaan solid, semisolid, liquid berturut-turut: 21, 20, dan 9%) dan pemusnahan obat (jawaban benar sediaan solid, semisolid, liquid berturut-turut: 9, 9, dan 8%). Data postest menunjukan terjadinya peningkatan pengetahuan masyarakat tentang penyimpanan obat (jawaban benar sediaan solid, semisolid, liquid berturut-turut: 90, 87, dan 85%) dan pemusnahan obat (jawaban benar sediaan solid, semisolid liquid berturut-turut: 78, 81, dan 82%). Hasil postest menunjukkan peningkatan pengetahuan masyarakat terhadap penyimpanan dan pemusnahan obat yang berbeda signifikan jika dibandingkan terhadap data pretest sebelum dilakukan edukasi (P<0.05). Kesimpulan: Metode edukasi melalui penyuluhan, tutorial dan praktik penyimpanan dan pemusnahan obat sangat efektif dan efisien dalam meningkatkan pengetahuan masyarakat.
Determination of sun protection factor and antioxidant properties of cream formulation of kencur (Kaempferia galanga L) and temu kunci (Boesenbergia pandurata (Roxb.) Schlecht) rhizomes extract Charisma, Shintia Lintang; Rahayu, Wiranti Sri; Wahyuingrum, Retno
Pharmaciana Vol. 8 No. 2 (2018): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v8i2.11891

Abstract

Kencur (Kaempferia galanga, L.) rhizome contain ethyl-p-methoxycinnamate (EPMS) which has sunscreen properties. Temu kunci (Boesenbergia pandurata (Roxb) Schlecht) rhizome contains flavonoid and essential oils with radical scavenging properties. The aims of this study were to obtain the optimum physical properties of sunscreen and antioxidant cream and to compare the sun protection factor (SPF) values and antioxidant activity of kencur and temu kunci rhizomes extract before and after formulated. This research used Simplex Latice Design (SLD) model with 2 components of kencur extract and temu kunci extract. Based on the SLD model obtained optimum formula design, then the SPF values and antioxidant activity were studied by UV spectrophotometric method and DPPH method respectively. Based on SLD model obtained optimum formula that containing kencur : temu kunci extract 80%:20% (formula A) and 70%:30% (formula B). The SPF values of kencur extract, formula A and formula B were 4.505, 5.024 and 4.511 respectively. Antioxidant activity showed that the IC50 of formula A, formula B, temu kunci extract, BHT and Vitamin E were 109.15 μg/mL, 95.23 μg/mL, 10.20 μg/mL, 22.33 μg/mL and 8.78 μg/mL respectively. Cream formula A and formula B have optimum physical properties. The SPF value of the optimum formulations were higher than SPF value of kencur extract. Antioxidant activity of that combinations were lower than temu kunci extract, BHT and Vitamin E.
QUALITY CHARACTERIZATION AND ANTIOXIDANT PROPERTIES OF ROSE PERIWINKLE CRUDE DRUGS Hartanti, Dwi; Charisma, Shintia Lintang; Rinawati, Jeri; Hamad, Alwani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 1 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i1.2320

Abstract

Leaves and flowers of rose periwinkle (Catharanthus roseus (L.) G. Don) are used for traditional diabetes management in Banyumas, Indonesia. This study evaluated the selected quality characters, total flavonoid content (TFC), total phenolic content (TPC), and the antioxidant activities of rose periwinkle crude drugs. Plant materials were collected from three locations in the Baturraden and Sumbang subdistricts and dried using an artificial heat drying rack to obtain crude drugs. The crude drugs' quality characters, TFC, TPC, and antioxidant activities were evaluated using standard methods. The quality characters of the crude drugs were specified as follows: loss on drying (9.12±0.50%), total ash (8.20±0.71%), acid-insoluble ash (0.24±0.06%), water extractable (28.82±6.77%), and ethanol extractable (35.17±1.79%). The chromatographic profile was generated from chloroform-methanol (8:2) separation over silica GF254. The TFC and TPC were 7.66±0.48 mg Quercetin equivalent (QE)/g and 7.27±1.07 mg Gallic acid equivalent (GAE)/g, respectively. The antioxidant activities were 148.95±12.00 Trolox equivalent (TE)/g for DPPH radical scavenging activity and 651.14±77.91 mM TE/g for FRAP. The DPPH radical scavenging activity and FRAP were weakly to moderately correlated to TPC and TFC. The phenolic compound and flavonoid contents of physicochemically-characterized rose periwinkle were not significantly correlated to their antioxidant activities.
Co-Authors Alwani Hamad Binar Asrining Dhiani Dwi Hartanti Hariyanti Hariyanti Retno Wahyuningrum Rinawati, Jeri Wahyuingrum, Retno Wiranti Sri Rahayu