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All Journal Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Nursing Care and Health Technology Journal (NCHAT)
Intan Keumala Dewi
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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PERITONITIS BAKTERIAL SPONTAN DAN PENGARUH PENGHAMBAT POMPA PROTON PADA PENDERITIA SIROSIS HATI Lelosutan, Syafruddin; Sakura Muhammad Tola; Intan Keumala Dewi; Endah Purnamasari; Diniwati Mukhtar; Muhammad Samsul Mustofa; Himmi Marsiati
Medika Alkhairaat: Jurnal Penelitian Kedokteran dan Kesehatan Vol 6 No 3 (2024): Desember
Publisher : Fakultas Kedokteran Universitas Alkhairaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31970/ma.v6i3.224

Abstract

Abstract. Spontaneous bacterial peritonitis (SBP) is an acute infection of ascitic fluid in the abdominal cavity (ACAF - ascitic fluid that accumulates in the abdominal cavity) in patients with portal hypertension who experience ascites and is a serious complication of internal medical emergencies in patients with Liver cirrhosis (SH) and nephrotic syndrome (SN). A pathophysiological condition that may be contaminating, such as contamination of dialysate fluid in patients with chronic renal failure (CKD) who receive peritoneal dialysis (PD) or that stimulates the transmission of germs, such as long-term use of proton pump inhibitors (PPI) in SH sufferers, could be an infectious etiology. The pathophysiology of SBP in SH is an inoculation of bacteria in the form of intestinal organisms in ACAF which most likely (> 90%) comes from bacterial contamination due to transmission of germs from the gastrointestinal tract in the presence of enteric microorganism endotoxin which is a direct transmural migration (DTM) of hollow and solid organ bacteria. stomach (gastrointestinal system / esophago-gastro-duodenalis, small and large intestines and pancreatic-hepato-biliary system / pancreas, liver, gallbladder and its ducts); known as enteric bacterial translocation (EBT). Understanding the pathophysiological process of SBP is generally not paid much attention by clinical practitioners, let alone understanding what types of germs are in ascitic fluid. This can be seen from the rare critical assessment (culture and cytology) of the existing ascitic fluid, perhaps even thinking about the presence or absence of ascites at the start of a case of liver cirrhosis (SH). General results show that SH patients who receive PPI therapy appear to experience SBP more often than those who do not receive PPI therapy in their treatment. This review aims to be a critical review of the use of PPIs in liver cirrhosis sufferers to warn of the risk of germ migration from the gastrointestinal tract to ascitic fluid which might cause SBP. Study and understand the literature relating to the management of SBP and the risks of using PPIs in liver cirrhosis sufferers. Gain an understanding of the risks of using PPIs in liver cirrhosis sufferers.
Gambaran Metode Diagnosis Infeksi Saluran Kemih di Puskesmas Kecamatan Tanjung Priok Anandani, Adinta; Ferdiana, Fita; Intan Keumala Dewi
Nursing Care and Health Technology Journal (NCHAT) Vol. 6 No. 1 (2026): Nursing and Health Care Technology-January to June Period
Publisher : Progres Ilmiah Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56742/nchat.v6i1.255

Abstract

Diagnosis ISK umumnya ditegakkan berdasarkan gejala klinis, pemeriksaan urinalisis, dan kultur urin, namun keterbatasan fasilitas di layanan primer sering menyebabkan diagnosis hanya berpedoman pada keluhan klinis. Penelitian ini bertujuan untuk mengetahui gambaran karakteristik klinis serta metode diagnosis ISK yang digunakan di Puskesmas Kecamatan Tanjung Priok. Penelitian menggunakan desain deskriptif retrospektif dengan data sekunder dari rekam medis pasien ISK tahun 2024–2025. Data dari 284 rekam medis dianalisis secara kuantitatif dan disajikan dalam bentuk table distribusi. Hasil penelitian ini menunjukkan bahwa ISK lebih banyak terjadi pada perempuan (70%) dibanding laki-laki (30%), dengan kelompok usia terbanyak 26–35 tahun (29%). Gejala yang paling banyak dilaporkan adalah nyeri saat berkemih (80%), diikuti nyeri pinggang (21%) dan nyeri perut bawah (19%), sementara demam hanya muncul pada 15% pasien. Pemeriksaan laboratorium urinalisis hanya dilakukan pada 10% pasien, dan hanya sebagian kecil parameter yang tercatat, seperti mikroskopik (71%), nitrit (50%), dan leukosit esterase (21%). Minimnya pemeriksaan penunjang menunjukkan bahwa penegakan diagnosis lebih banyak bergantung pada gejala klinis. Kesimpulan penelitian ini menegaskan perlunya optimalisasi pemeriksaan urinalisis dan pencatatan medis yang lebih lengkap untuk meningkatkan akurasi diagnosis ISK di layanan primer.
Co-Authors Anandani, Adinta Diniwati Mukhtar Endah purnamasari Ferdiana, Fita Himmi Marsiati Lelosutan, Syafruddin Muhammad Samsul Mustofa Sakura Muhammad Tola