Article Per Year (5 Year)
p-Index From 2020 - 2025
0.888
P-Index
This Author published in this journals
All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Berkala Ilmu Kesehatan Kulit dan Kelamin HIGEIA (Journal of Public Health Research and Development) Public Health and Preventive Medicine Archive
Awanis, Ghina Shabrina
Unknown Affiliation
Immunology & microbiology Neuroscience Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Faktor-Faktor yang Dapat Memengaruhi Keseimbangan Th17/Treg: Review Article Prakoeswa, Flora Ramona Sigit; Hidayat, Saiful; Satria, Yohanes Aditya Adhi; Awanis, Ghina Shabrina
HIGEIA (Journal of Public Health Research and Development) Vol 6 No 1 (2022): HIGEIA: January 2022
Publisher : Jurusan Ilmu Kesehatan Masyarakat, Fakultas Ilmu Keolahragaan, Universitas Negeri Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/higeia.v6i1.50196

Abstract

Abstrak Sistem imun manusia terdiri dari sistem imun alami dan adaptif. Sistem imun alami berperan sebagai pertahanan pertama tubuh terhadap pathogen, sedangkan sistem imun adaptif berperan dalam menjalankan respon imun spesifik. Di antara berbagai efektor sistem imun adaptif, Th17 yang bertugas melawan pathogen dapat menimbulkan terjadinya autoimun dan inflamasi ketika jumlahnya berlebih. Sebaliknya, Treg yang bertugas menjaga homeostasis imun dapat menyebabkan terjadinya autoimun ketika jumahnya menurun. Ketidakseimbangan antara Th17 dan Treg berperan penting dalam patogenesis berbagai penyakit autoimun, seperti systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), inflammatory bowel disease (IBD), multiple sclerosis (MS), dan psoriasis. Artikel ini dibuat untuk mengevaluasi faktor-faktor yang dapat memengaruhi keseimbangan Th17 dan Treg sehingga dapat digunakan sebagai pendekatan terapeutik tambahan dalam merawat pasien-pasien autoimun. Beberapa hal yang dapat dilakukan untuk mengembalikan keseimbangan Th17 dan Treg di antaranya adalah pemberian suplemen vitamin D, paparan terhadap sinar matahari, paparan terhadap mikrobiota, dan pengaturan diet. Abstract The human immune system consists of the innate and adaptive immune systems. The innate immune system acts as the body's first defense against pathogens, while the adaptive immune system plays a role in carrying out specific immune responses. Among the various effects of the adaptive immune system, Th17 which is in charge of fighting pathogens can induce inflammation and autoimmune when there is an excessive amount of them. On the other hand, Tregs that maintain immune homeostasis can lead to autoimmunity when their amount is low. The imbalance between Th17 and Tregs plays an important role in the pathogenesis of various autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), inflammatory bowel disease (IBD), multiple sclerosis (MS), and psoriasis. This article is aimed to evaluate factors that can affect Th17 and Treg balance so that they can be used as an adjuvant treatment for autoimmune patients. Some things that can be done to restore the balance of Th17 and Tregs include supplementation of vitamin D, exposure to sunlight, exposure to microbiota, and dietary regulation. Keywords: autoimmune, Th17/Treg balance, therapy
Topical anti-aging agents: state-of-the-art review Prakoeswa, Flora Ramona Sigit; Maharani, Faradiba; Satria, Yohanes Aditya Adhi; Awanis, Ghina Shabrina; Febrianty, Astrida Fesky
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 55, No 4 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005504202310

Abstract

Skin aging can be divided into intrinsic and extrinsic aging. Even though it is inevitable, symptoms of skin aging are a common concern for patients. As a result, there is a surge in the making of anti-aging cosmeceuticals. However, there is a lack of evidence-based data to support the usage of topical preparations as anti-aging treatments. Therefore, further studies are needed to explore topical treatment options for skin aging. This literature review discusses the mechanism of commonly used topical anti-aging agents and their adverse reactions.
The increase of asthma self-medication in Indonesia during COVID-19 Pandemic: An infodemiology study using Google Trends Setiawan, Hendri; Rahmah, Atika; Hartanto, Nadira Rachmianti; Awanis, Ghina Shabrina
Public Health and Preventive Medicine Archive Vol. 12 No. 2 (2024)
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53638/phpma.2024.v12.i2.p03

Abstract

Background and purpose: The COVID-19 pandemic has significantly interrupted the care of asthma patients. In order to determine whether online search data and the number of COVID-19 cases were related, many Google Trends-based investigations were carried out throughout the pandemic. This study investigates whether asthma patients use the internet for self-management and treatment advice. Methods: A netnographic approach with data sources from Google Trends was used in our research. The data were taken from www.https://trends.google.co.id and were collected within two timeframes: (1) the beginning of COVID-19 (March 2, 2018-March 1, 2020) and (2) during the pandemic COVID-19 (March 2, 2020-March 1, 2022). The data is displayed graphically on a scale of 0 to 100, referred to as the Relative Search Volume (RSV). The Spearman correlation test on each keyword and the confirmed cases of COVID-19 in Indonesia were done in SPSS version 25 (IBM Corp., Armonk, NY) to determine if a correlation existed. Results: This study found an increased search volume for asthma therapy. According to the correlation test results, the keywords "inhaler" and "nebulizer" significantly correlated with the number of confirmed COVID-19 cases. However, no link between asthma symptoms and the number of COVID-19 was found. Conclusion:Indonesians sought more information on asthma self-medication during the rise of COVID-19, however not directly associated with the prevalence of the disease. Google Trends can become a potential source to explore people behaviour in relation to certain health information, however it cannot be used as the sole data collection tool for health research, especially in Indonesia.
Immunodermatology: at a glance Prakoeswa, Flora Ramona Sigit; Awanis, Ghina Shabrina; Sari, Winda Atika; Pramuningtyas, Ratih
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 2 (2025): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.2.2025.130-141

Abstract

Background: Immunodermatology is a medical specialty specializing in detecting and treating skin conditions induced by a compromised immune system response. Each cellular element of the skin undergoes a unique developmental process and serves a specific function within the skin. Many disorders affecting epithelial organs, including the skin, mucous membranes, digestive tract, and respiratory tracts, require immunodermatological testing for diagnosis and treatment. Immunodermatology, a field at the intersection of dermatology and immunology, continues to evolve, with new research being published annually. Purpose: This review aims to summarize the foundational principles of immunodermatology, current diagnostic approaches, and selected immune-mediated skin disorders. Review: There are numerous dermatological conditions related to immunodermatology. Advances in immunology and dermatology have enhanced our understanding of the skin as an active immune organ. Immunodermatology encompasses a wide range of diseases involving both innate and adaptive immunity. Despite growing research, many aspects remain under investigation. Conclusion: The skin’s immunological function could be viewed as a complex and multifaceted interplay between signal processing and defense reactions. Immunodermatology continues to expand with ongoing innovations in diagnostics and therapeutics, highlighting its importance in future clinical and research developments.
Co-Authors Febrianty, Astrida Fesky Flora Ramona Sigit Prakoeswa Hartanto, Nadira Rachmianti Hendri Setiawan Maharani, Faradiba Rahmah, Atika Ratih Pramuningtyas Saiful Hidayat Sari, Winda Atika Satria, Yohanes Aditya Adhi