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Differences in Mean Anti-Pertussis Antibody Levels in Children with Acellular Pertussis Immunization and Whole Pertussis Without Booster Rezki, Wenny Rahmalia; Rinang Mariko; Rizanda Machmud; Rusdi; Asrawati; Indra Ihsan
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 7 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i7.1022

Background: The incidence of pertussis is increasing every year, especially in developing countries. Low immunization coverage and decreased immunity are some of the factors causing the re-increase in pertussis cases. The protection provided by the pertussis vaccine whole and acellular pertussis given as a baby will decrease with age. This study aims to determine the difference in mean levels of anti-pertussis antibodies in children who received acellular pertussis and whole pertussis immunization without a booster. Methods: A cross-sectional study was carried out at the pediatric polyclinic of Dr. M. Djamil General Hospital Padang from December 2022 to December 2023. Research subjects were children aged 5-9 years with a history of whole pertussis immunization (DPwT) 3 times or acellular pertussis immunization (DPaT) 3 times. The research subjects were examined for anti-pertussis antibody titers using the ELISA technique. Results: Thirty-four children with a history of DPwT immunization 3 times and 34 children with a history of DPwT immunization 3 times were research subjects, with mean age 6.94±1.49 in the DPwT group and 6.88 ±1.61 in the DPaT group. The mean anti-pertussis antibody level in the DPwT group (9.54 IU/mL) was higher than the DPaT group (6.96 IU/mL) but was not statistically significant (p>0.05). The average antibody results showed that the antibody levels in both groups were below the antibody titer threshold that provides protection against pertussis. The results of the analysis showed that there was a significant difference in the incidence of AEFI between the DPwT and DPaT immunization groups (p<0.05). Conclusion: There was no difference in anti-pertussis antibody levels in children who received DPwT and DPaT immunization 3 times. Pertussis immunization is a required booster so that antibody levels are sufficient to provide protection against pertussis.

Analisis Skor Reflux Symptom Index (RSI) pada Pasien Laryngopharyngeal Reflux dengan Pemberian Lansoprazol dan Ranitidin di RSUP Dr M Djamil Padang Adha, Muhammad Rofid; Asyari, Ade; Asrawati; Usman, Elly; Putra, Syandrez Prima
Jurnal Otorinolaringologi Kepala dan Leher Indonesia Vol. 3 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jokli.v3i1.60

Laryngopharyngeal reflux (LPR) is a condition caused by the movement of stomach acid back into the pharynx, larynx and upper digestive tract. One of the diagnostic tools that can be used in LPR is the Reflux Symptom Index (RSI), where RSI can also be used to evaluate symptom improvement in patients before and after administering drug therapy. This study aims to determine the average RSI score before and after giving therapy to LPR patients at Dr M Djamil Hospital, Padang. This research is a retrospective analytical study by taking medical record data on LPR patients at Dr M Djamil Hospital Padang using consecutive sampling techniques. Data analysis was carried out univariately to determine the frequency distribution and bivariately using the paired T-test to analyze the average RSI score. The results of this study were that the majority of LPR sufferers were >50 years old (52.9%), the majority gender was female (76.2%), and the most common complaints were a lump in the throat (100%) and heartburn (100%). The average RSI score before giving therapy was found to be 22.12 ± 6.827 and after giving therapy was 13.18 ± 7.844. Based on the data analysis carried out, the p<0.001. The conclusion of this study was that there was a significant change in the average RSI value before and after administration of lansoprazole and ranitidine therapy in LPR patients.

Naive Bayes dan Decision Tree: Studi Kasus Klasifikasi Kepuasan Pelanggan E-Commerce Tulak Bamba, Ofirmince; Nur Vadila; Sri Fitrawati; Tedang, Vilna Wati; Asrawati
Jurnal Sistem Informasi dan Sistem Komputer Vol 10 No 2 (2025): Vol 10 No 2 - 2025
Publisher : STIMIK Bina Bangsa Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51717/simkom.v10i2.897

Peningkatan belanja daring mendorong e-commerce untuk memahami kepuasan pelanggan melalui analisis ulasan otomatis. Studi ini mengevaluasi dan membandingkan kemampuan algoritma Naive Bayes dan Decision Tree dalam mengklasifikasikan tingkat kepuasan berdasarkan 5.000 ulasan dari platform Olist. Ulasan dikategorikan ke dalam tiga kelas, yaitu Tidak Puas, Netral, dan Puas. Pra-pemrosesan meliputi pembersihan data, ekstraksi fitur dengan TF-IDF, dan pembagian data 80% latih dan 20% uji. Evaluasi menggunakan metrik accuracy, precision, recall, F1-score, dan AUC. Naive Bayes menunjukkan akurasi lebih tinggi (80,70%) dibanding Decision Tree (73,90%) serta performa klasifikasi yang lebih stabil. Dengan demikian, Naive Bayes lebih efisien untuk klasifikasi kepuasan pelanggan berbasis teks pada ulasan e-commerce.

Differences in Mean Anti-Pertussis Antibody Levels in Children with Acellular Pertussis Immunization and Whole Pertussis Without Booster Rezki, Wenny Rahmalia; Rinang Mariko; Rizanda Machmud; Rusdi; Asrawati; Indra Ihsan
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 7 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i7.1022

Background: The incidence of pertussis is increasing every year, especially in developing countries. Low immunization coverage and decreased immunity are some of the factors causing the re-increase in pertussis cases. The protection provided by the pertussis vaccine whole and acellular pertussis given as a baby will decrease with age. This study aims to determine the difference in mean levels of anti-pertussis antibodies in children who received acellular pertussis and whole pertussis immunization without a booster. Methods: A cross-sectional study was carried out at the pediatric polyclinic of Dr. M. Djamil General Hospital Padang from December 2022 to December 2023. Research subjects were children aged 5-9 years with a history of whole pertussis immunization (DPwT) 3 times or acellular pertussis immunization (DPaT) 3 times. The research subjects were examined for anti-pertussis antibody titers using the ELISA technique. Results: Thirty-four children with a history of DPwT immunization 3 times and 34 children with a history of DPwT immunization 3 times were research subjects, with mean age 6.94±1.49 in the DPwT group and 6.88 ±1.61 in the DPaT group. The mean anti-pertussis antibody level in the DPwT group (9.54 IU/mL) was higher than the DPaT group (6.96 IU/mL) but was not statistically significant (p>0.05). The average antibody results showed that the antibody levels in both groups were below the antibody titer threshold that provides protection against pertussis. The results of the analysis showed that there was a significant difference in the incidence of AEFI between the DPwT and DPaT immunization groups (p<0.05). Conclusion: There was no difference in anti-pertussis antibody levels in children who received DPwT and DPaT immunization 3 times. Pertussis immunization is a required booster so that antibody levels are sufficient to provide protection against pertussis.

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