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Differences in Mean Anti-Pertussis Antibody Levels in Children with Acellular Pertussis Immunization and Whole Pertussis Without Booster Rezki, Wenny Rahmalia; Rinang Mariko; Rizanda Machmud; Rusdi; Asrawati; Indra Ihsan
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 7 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i7.1022

Abstract

Background: The incidence of pertussis is increasing every year, especially in developing countries. Low immunization coverage and decreased immunity are some of the factors causing the re-increase in pertussis cases. The protection provided by the pertussis vaccine whole and acellular pertussis given as a baby will decrease with age. This study aims to determine the difference in mean levels of anti-pertussis antibodies in children who received acellular pertussis and whole pertussis immunization without a booster. Methods: A cross-sectional study was carried out at the pediatric polyclinic of Dr. M. Djamil General Hospital Padang from December 2022 to December 2023. Research subjects were children aged 5-9 years with a history of whole pertussis immunization (DPwT) 3 times or acellular pertussis immunization (DPaT) 3 times. The research subjects were examined for anti-pertussis antibody titers using the ELISA technique. Results: Thirty-four children with a history of DPwT immunization 3 times and 34 children with a history of DPwT immunization 3 times were research subjects, with mean age 6.94±1.49 in the DPwT group and 6.88 ±1.61 in the DPaT group. The mean anti-pertussis antibody level in the DPwT group (9.54 IU/mL) was higher than the DPaT group (6.96 IU/mL) but was not statistically significant (p>0.05). The average antibody results showed that the antibody levels in both groups were below the antibody titer threshold that provides protection against pertussis. The results of the analysis showed that there was a significant difference in the incidence of AEFI between the DPwT and DPaT immunization groups (p<0.05). Conclusion: There was no difference in anti-pertussis antibody levels in children who received DPwT and DPaT immunization 3 times. Pertussis immunization is a required booster so that antibody levels are sufficient to provide protection against pertussis.
Analysis of the Implementation of Minimum Service Standards (SPM) on the Minimum Service Quality of Hospitals: A Case Study at Mentawai Islands Regional Hospital, West Sumatera, Indonesia Fadlika, Avissa; Rizanda Machmud; Abdi Setya
Community Medicine and Education Journal Vol. 5 No. 2 (2024): Community Medicine and Education Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/cmej.v5i2.593

Abstract

Minimum service standards (SPM) are an important instrument in ensuring the quality of health services in hospitals. This research aims to analyze the implementation of SPM on minimum service quality at the Mentawai Islands Regional Hospital, West Sumatera, Indonesia. This research uses a mixed-method design with a sequential explanatory approach. The quantitative phase involved collecting secondary data from medical records and patient satisfaction surveys (n=300). Logistic regression analysis is used to identify the relationship between SPM implementation and service quality. The qualitative stage involved in-depth interviews with hospital management (n=5) and health workers (n=10) to explore factors influencing SPM implementation. The results of the quantitative analysis show that the implementation of SPM is significantly associated with an increase in minimum service quality, especially in the aspects of patient safety, clinical effectiveness and patient experience. Qualitative interviews revealed that factors such as resource availability, management commitment, and staff training influence the success of SPM implementation. Effective implementation of SPM contributes to improving the minimum service quality at the Mentawai Islands Regional Hospital. To optimize the implementation of SPM, increasing the availability of resources, strengthening management commitment and ongoing training programs for staff is needed.
HUBUNGAN SUPERVISI KEPALA RUANGAN DENGAN PENERAPAN PATIENT SAFETY PENGURANGAN RISIKO PASIEN JATUH DIRUANG RAWAT INAP RSI SITI RAHMAH PADANG Rikayoni Rikayoni; Rizanda Machmud; Syafrida Syafrida
Jurnal Kesehatan Medika Saintika Vol 14, No 1 (2023): Juni 2023
Publisher : Stikes Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jkms.v14i1.2123

Abstract

Patient safety yaitu pasien bebas dari cedera yang seharusnya tidak terjadi atau bebas dari cedera yang potensial terjadi akibat pelayanan kesehatan.Risiko jatuh adalah suatu risiko untuk terjadinya suatu peristiwa di mana seorang mengalami jatuh dengan atau tanpa disaksikan oleh orang lain, tak disengaja/tak direncanakan, dengan arah jatuh ke lantai, dengan atau tanpa mencederai dirinya. Lebih dari 500.000 kejadian pasien jatuh di seluruh rumah sakit dan Kongres XII PERSI (2012) melaporkan bahwa kejadian pasien jatuh tercatat sebesar 14% di Indonesia.Hasil survey yang dilakukan masih ditemukan perawat pelaksana yang belum menerapkan patient safety.Penelitian ini bertujuan untuk mengetahui hubungan supervisi kepala ruangan dengan penerapan patient safety pengurangan risiko pasien jatuh di ruang rawat inap RSI Siti Rahmah Padang.Penelitian ini berjenis kuantitatif dengan desain cross sectional. Sampel berjumlah 55 perawat diruang rawat inap RSI Siti Rahmah Padang, diambil dengan menggunakan teknik total sampling. Teknik pengumpulan data dengan menyebarkan kuesioner dan lembar observasi dokumentasi. Kesimpulan dari penelitian ini adalah lebih dari separuh penerapan patient safety pengurangan risiko pasien jatuh di ruang rawat inap RSI Siti Rahmah Padang pada kategori kurang baik (58%) dan lebih dari separuh supervisi kepala ruangan di ruang rawat inap RSI Siti Rahmah Padang pada kategori kurang baik (64%) dan ada hubungan supervisi kepala ruangan dengan penerapan patient safety pengurangan risiko pasien jatuh di ruang rawat inap RSI Siti Rahmah Padang dengan nilai p=0,004. Diharapkan pihak manajerial rumah sakit dapat meningkatkan peran supervisi kepala ruangannya dengan mengikutsertakan kepala ruangan pada pelatihan-pelatihan yang dapat meningkatkan keterampilan kepala ruangan dalam melakukan supervisi kepada perawat pelaksana.Kata Kunci   :Kepala ruangan, supervisi, penerapan patient safety, resiko jatuh
Unraveling the Link between Obesity and Tuberculosis: A Systematic Review of the Underlying Mechanisms Deddy Herman; Rizanda Machmud; Nur Indrawaty Lipoeto
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 2 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i2.1205

Abstract

Background: Tuberculosis (TB) and obesity are significant global health concerns with potentially complex interactions. Obesity, through its effects on metabolism, inflammation, and the immune system, may influence TB susceptibility, progression, and treatment outcomes. This systematic review aims to analyze the published literature on the relationship between obesity and TB, focusing on the underlying mechanisms. Methods: A systematic search of PubMed, Science Direct, and Google Scholar was conducted for articles published in the last 10 years. The search strategy included keywords such as "tuberculosis," "TB," "obesity," and "BMI." Articles were selected using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) method. Results: The review identified 11 studies that met the inclusion criteria. The studies revealed a complex relationship between obesity and TB, with nutritional status, immunity, and diabetes mellitus (DM) playing key roles. Obesity can alter the immune response to TB, potentially increasing the risk of disease and affecting treatment efficacy. Conclusion: The relationship between obesity and TB is multifaceted, with obesity potentially influencing both disease susceptibility and outcomes. Further research is needed to fully elucidate the underlying mechanisms and to develop targeted interventions for individuals with both obesity and TB.
Iron Deficiency and Anemia of Inflammation in Tuberculosis: A Systematic Review of the Evidence Deddy Herman; Rizanda Machmud; Nur Indrawaty Lipoeto
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 2 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i2.1207

Abstract

Background: Tuberculosis (TB) remains a major global health problem, with anemia being a frequent comorbidity. Anemia in TB is multifaceted, with iron deficiency and anemia of inflammation (AI) being the most common types. This systematic review aims to synthesize the evidence on iron deficiency and AI in TB, their prevalence, impact on outcomes, and management strategies. Methods: A systematic search of PubMed and ScienceDirect databases was conducted for articles published in the last 10 years. Observational studies examining the prevalence, types, and impact of anemia on TB outcomes were included. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Results: The review included 7 studies involving 1,133 participants. Anemia prevalence ranged from 61% to 89% in TB patients. AI was the predominant type, with iron deficiency also prevalent. Anemia was associated with increased mortality, delayed sputum culture conversion, and impaired TB treatment response. Conclusion: Anemia, primarily AI and iron deficiency, is highly prevalent in TB and negatively impacts treatment outcomes and survival. Effective management of anemia is crucial for improving TB outcomes. Further research is needed to optimize diagnostic and treatment strategies for iron deficiency and AI in TB.
The Relationship of Employee Engagement, Quality of Work Life and Organizational Commitment with Turnover Intention Nurse from Unand Padang Hospital in 2023 Engga Lift Irwanto; Rizanda Machmud; Yuniar Lestari
International Journal of Health and Medicine Vol. 1 No. 3 (2024): July : International Journal of Health and Medicine
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhm.v1i3.35

Abstract

This research was conducted with the aim of analyzing the relationship between the implementation of employee engagement, quality of work life and organizational commitment to nurses at Unand Hospital in 2023. This research was carried out at Unand Hospital throughout 2024 using a mix methods research method . This method was used. This was carried out with the aim of knowing the frequency distribution of the relationship between employee engagement, quality of work life and organizational commitment to the turnover intention of nurses at Unand Hospital and being able to explain this further through informant interviews. The research results then showed that there was a negative relationship between the employee engagement of nurses at Unand Hospital, the lower the level of turnover intention of nurses at Unand Hospital, the quality of work-life of nurses had a negative and significant effect on the turnover intention of nurses at Unand Hospital and organizational commitment had a negative and significant effect on the turnover intention of nurses at Unand Hospital. significant impact on the turnover intention of nurses at Unand Hospital. So this shows that if the implementation of employee engagement , quality of work life and organizational commitment is increasingly improved, the level of turnover intention that occurs will decrease. This was also expressed by nurses who stated their low level of turnover intention. while working at Unand Hospital due to the comfort of work, harmony with co-workers and greater career and study opportunities at Unand Hospital. So it is hoped that Unand Hospital will maintain the quality and quantity of its human resources by increasing employee engagement, quality of work life and organizational commitment so that it has an impact on the quality of service delivery to the public.
Collaborative Intervention Assistance Model In An Effort To Increase The Quality Of Pregnant Women Services To Reduce Maternal Mortality In Padang City Adnani, Syahredi; Rizanda Machmud; Dwiana Ocviyanti
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.667-674.2024

Abstract

Background : Maternal death, as defined by WHO, includes deaths during pregnancy or within 42 days postpartum due to pregnancy-related causes. The Maternal Mortality Rate (MMR) quantifies maternal deaths per 100,000 live births. A key target of the Millennium Development Goals (MDGs) was reducing the MMR by three-quarters between 1990 and 2015, aiming for a global rate under 70 per 100,000 by 2030. In Indonesia, the 2012 Demographic and Health Survey reported an MMR of 359 per 100,000 live births, with West Sumatra at 212 per 100,000. Objective : This study employs a mixed-method approach, focusing on pregnant women visiting health centers in Padang City, to assess an intervention model. Result : Maternal mortality in Indonesia is mainly caused by bleeding, eclampsia, and infections, with contributing factors including delayed care access, socio-cultural, educational, and economic challenges. Significant health issues include hypertensive disorders, diabetes, acute kidney injury, jaundice, and thyroid disease. Low educational and economic levels in rural areas correlate with higher maternal morbidity and mortality. Government efforts, such as the Maternity Guarantee (Jampersal) and the Maternal and Child Health (KIA) Handbook, aim to improve maternal health but face challenges due to poor resource utilization. Conclusion : Indonesia struggles to meet maternal mortality reduction targets, with rates high compared to other Asian countries. Effective interventions must address both direct and indirect causes of maternal deaths, improve education and economic conditions, and enhance healthcare access. Government programs show promise but require better implementation and community engagement to reduce maternal mortality rates effectively.
Effect Modification of Modifiable Cardiovascular Risk Factors : A Hospital-Based Matched Case Control Study Defriman Djafri; Monalisa Monalisa; Fauziah Elytha; Rizanda Machmud
Jurnal Kesehatan Masyarakat Andalas Vol 11 No 2 (2017): Jurnal Kesehatan Masyarakat Andalas
Publisher : Faculty of Public Health, Andalas University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24893/jkma.v11i2.280

Abstract

This study aims to find the role of modifiable risk faktors toward the association between hypertension and coronary heart disease in RSUP DR. M. Djamil Padang, in 2016This match case control study was conducted from Desember 2014 to April 2015. We studied 171 samples with 1:2 ratio between the case and the control. Samples are collection using simple random sampling by matching the age and sex. Data through the medical record (secondary data) in RSUP DR. M. Djamil. Bivariate analysis showed that hypertension had OR=16,04 (95%CI 5.705-45.12), obesitas had OR=2.53 (95%CI 1.321-4.844), and hyperusrisemia had OR 2.41 (95%CI 1.292-4.516. Multivariate modeling showed that hyperurisemia had a confounder between assosiated hypertension and Coronary heart disease. Multivariate modeling showed hypertension had the highest risk to coronary heart disease. Obesity and hyperurisemia were associated between hypertension and coronary heart disease. Hypertension were considered as determinant of coronary heart disease. People are expected to manage their blood pressure to decrease the risk of coronary heart disease.