Article Per Year (5 Year)
p-Index From 2021 - 2026
0.61
P-Index
This Author published in this journals
All Journal JKPK (Jurnal Kimia dan Pendidikan Kimia) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Bioteknologi & Biosains Indonesia
Muslimah, Intan
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
TRANSDERMAL PATCH PILIS FROM TURMERIC RHIZOME AND BLACK SEEDS FOR TREATMENT BASED ON ETHNOPHARMACY Susanto, Nindita Clourisa Amaris; Sawitri, Arinda Handiyah; Muslimah, Intan
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.4870

Abstract

Pilis, a traditional product containing various herbal ingredients, is currently less desir-able due to its impractical and unfashionable method of application. Pilis is used to treat dizziness, pain, eye fatigue, encephalitis in children, fever, and to aid recovery for mothers after childbirth. However, pilis also carries risks related to uncontrolled dosage and contamination, particularly from chemical or heavy metal pollutants, which may cause toxic reactions. To mitigate these risks, pilis should be used in recommended doses and produced under clean and safe conditions. This research aimed to provide the innovation of patches as an alternative treatment to increase attractiveness and control the active substances released and delivered for a long time. Transdermal patches are made from a combination of turmeric and black seed containing flavonoid active metabolite compounds, namely curcumin, carotenoids, quercetin, kaempferol, and apigenin. The combination has a synergistic effect that can increase total flavonoid levels and the therapeutic effect of pilis. The method used in this research was litera-ture review and data analysis. The results showed the effect of transdermal patch pilis from the combined extracts added to the formula in vitro and in vivo using animal tests. In conclusion, transdermal patch pilis has prospects as a topical treatment based on the combination of an active delivery system with a patch and metered dose system.
TRANSDERMAL PATCH PILIS FROM TURMERIC RHIZOME AND BLACK SEEDS FOR TREATMENT BASED ON ETHNOPHARMACY Susanto, Nindita Clourisa Amaris; Sawitri, Arinda Handiyah; Muslimah, Intan
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.4870

Abstract

Pilis, a traditional product containing various herbal ingredients, is currently less desir-able due to its impractical and unfashionable method of application. Pilis is used to treat dizziness, pain, eye fatigue, encephalitis in children, fever, and to aid recovery for mothers after childbirth. However, pilis also carries risks related to uncontrolled dosage and contamination, particularly from chemical or heavy metal pollutants, which may cause toxic reactions. To mitigate these risks, pilis should be used in recommended doses and produced under clean and safe conditions. This research aimed to provide the innovation of patches as an alternative treatment to increase attractiveness and control the active substances released and delivered for a long time. Transdermal patches are made from a combination of turmeric and black seed containing flavonoid active metabolite compounds, namely curcumin, carotenoids, quercetin, kaempferol, and apigenin. The combination has a synergistic effect that can increase total flavonoid levels and the therapeutic effect of pilis. The method used in this research was litera-ture review and data analysis. The results showed the effect of transdermal patch pilis from the combined extracts added to the formula in vitro and in vivo using animal tests. In conclusion, transdermal patch pilis has prospects as a topical treatment based on the combination of an active delivery system with a patch and metered dose system.
Anti-Dandruff Shampoo Formulation from Rambutan Leaf Extract (Nephelium lappaceum L.) as Antifungal Malassezia furfur Azzahra, Hasna; Shalihah, Fianicha; Aeniah, Siti; Rahmawati, Inka Pungky; Ningrum, Paula Tyasmita Andar; Wardani, Salma Fauzia; Muslimah, Intan
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 8, No 1 (2023): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkpk.v8i1.72727

Abstract

A shampoo is a product that is used to maintain hair. The most common hair problem is dandruff. A microorganism that causes dandruff is Malassezia furfur. Malassezia furfur is the causative microorganism that infects the skin and scalp into dandruff. This fungus can grow quickly if the head has excess oil glands. Rambutan leaf extract contains secondary metabolites that can inhibit fungal growth. Alkaloids can inhibit the growth of fungi because fungi can grow well at a pH of 3,8 – 5,6. Flavonoids and tannins can cause damage to cell membrane proteins, causing changes in membrane permeability and fungal cell membrane lysis. Saponins can break down fungal cells. A shampoo formulation from Rambutan leaf extract sets it apart from other anti-dandruff shampoos because its herbal composition is safe and increases bioavailability benefits. The method used is laboratory experimental. This research procedure is making rambutan leaf extract using a rotary evaporator, making shampoo by compounding the formulation components, growing test mushrooms on PDA media, making test mushroom suspensions, and conducting the research and data collection. The result showed that shampoo from rambutan leaf extract has an inhibition zone diameter of 0.3 cm to 0.6 cm had a moderate growth inhibition response. The results of the antifungal activity test showed that the rambutan leaf extract shampoo concentration of 10%, 15% and 30% can inhibit the growth of fungi with the best inhibitory concentration at 30% in a strong category.
Co-Authors Aeniah, Siti Azzahra, Hasna Ningrum, Paula Tyasmita Andar Rahmawati, Inka Pungky Sawitri, Arinda Handiyah Shalihah, Fianicha Susanto, Nindita Clourisa Amaris Wardani, Salma Fauzia