Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal HAYATI Journal of Biosciences Borneo Journal of Medical Laboratory Technology
Shalihah, Fianicha
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Congenital Malformations in Chicken Embryos After Oxybenzone Exposure Saragih, Hendry T.S.; Empra, Desi Eka Putri; Rahmadian, Desti; Shalihah, Fianicha; Primahesa, Alfian; Oktaviana, Shintia; Allimi, Hayu Swari; Septriani, Nur Indah; Nuriliani, Ardaning
HAYATI Journal of Biosciences Vol. 32 No. 3 (2025): May 2025
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.32.3.589-598

Abstract

Topical use of oxybenzone, commonly found in sunscreens, can be absorbed by the skin, and long-term use may cause endocrine disruption, cancer, and teratogenic effects. However, its potential teratogenic effects on embryonic development have not been well-studied. This study aims to determine the impact of oxybenzone exposure on the early stage of embryonic development. Chicken embryos aged 72 hours (20 Hamburger-Hamilton/HH stage) were exposed to a pure oxybenzone for 24 hours at varying concentrations (0, 1, 5, 10, and 20 ppm), each group consisting of 3 embryos. Embryo preparations were made using the wholemount method. Morphological abnormalities were observed with a stereo microscope, and descriptively morphometric measurements were analyzed using ImageJ software. Statistical analysis used One-way ANOVA and Tukey’s test for normally distributed data, while Kruskal-Wallis H and Mann-Whitney U test for non-normally distributed data. This study found that oxybenzone significantly enlarged the embryo, telencephalon, and eye. Several abnormalities were observed in the embryos exposed to oxybenzone, including incomplete closure of the anterior neuropore, concavity in the anterior and lateral of the mesencephalon, and depressions in the tail bud. This study concludes that oxybenzone acts as a teratogen, causing abnormalities in embryonic development, particularly in the central nervous system.
Review: Aplikasi Histopatologi Untuk Praktik Forensik: Review: Applications of Histopathology for Forensic Practice Faulana, Arum Fahmi; Empra, Desi Eka Putri; Rahmadian, Desti; Shalihah, Fianicha; Nuriliani, Ardaning; Retnoaji, Bambang; Saragih, Hendry Tri Sakti SG; Rohmah, Zuliyati; Septriani, Nur Indah
Borneo Journal of Medical Laboratory Technology Vol. 6 No. 2 (2024): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v6i2.6582

Abstract

Forensics plays an important role in investigating crimes because it can reveal everything related to a murder case, including the time and cause of the murder. Histopathology is the study of damage to body tissues and organs which can be used to help investigate crimes. The aim of this literature review is to study the role of histopathology applications for forensic practice. The method used is searching journals and books using Google Scholar, ScienceDirect, NCBI, and PubMed with the keywords histopathology, forensics, diagnosis, death, microscopy, disease, staining, and autopsy. The histology approach helps the pathologist make a clear determination on the cause of death. The aim of histopathology is to perfect the macroscopic diagnosis and act as an additional examination in forensic case management. One of the histopathology methods in the forensic field is the paraffin method with hematoxylin eosin staining and special stains, immunohistochemistry, and MITS. The parameters observed with this method are measurements of pulmonary fat embolism; determining the age of myocardial infarction; assessment of liver steatosis, fibrosis, and cirrhosis; determination of the age of thrombus or thromboembolism; and diagnosis of shock with various diseases. The prospect of forensic histopathology is to complement molecular diagnostic methods, so that the combination of molecular and histology methods can play a maximum role in the field of forensic pathology. The conclusion of this literature review is that histopathology can be used to confirm the diagnosis in forensic cases and has good future prospects if combined with other methods such as molecular.
Co-Authors Allimi, Hayu Swari Ardaning Nuriliani Bambang Retnoaji Empra, Desi Eka Putri Faulana, Arum Fahmi Oktaviana, Shintia Primahesa, Alfian Rahmadian, Desti Rohmah, Zuliyati Saragih, Hendry T.S. Saragih, Hendry Tri Sakti SG Septriani, Nur Indah Septriani, Nur Indah