Muhamad Ayus Astoni
Bagian Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Gadjahmada Yogyakarta

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KOLANGITIS AKUT PADA PENDERITA TUMOR KLATSKIN Astoni, Muhamad Ayus; Bardiman, Syadra; Purwoko, Mitayani
Jurnal Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 5 (2018): MAGNA MEDICA
Publisher : Jurnal Berkala Ilmiah Kedokteran dan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (573.77 KB)

Abstract

Tumor Klatskin merupakan suatu kolangiokarsinoma tipe ekstrahepatik yang bersifat ganas dan timbul dari epitel duktus koledokus dan kedua percabangannya. Seorang wanita usia 47 tahun mengalami keluhanbadan panas sejak 1 hari sebelum masuk rumah sakit. Satu hari sebelum masuk rumah sakit, pasien mengalami demam tinggi terus- menerus, tidak disertai dengan menggigil. Keluhan disertai nyeri hebat di perut kanan atas sampai ke ulu hati, nafsu makan menurun, mual setiap hendak makan, BAK berwarna seperti teh, BAB biasa, dan mata terlihat kuning. Satu minggu sebelum masuk rumah sakit, keluhan nyeriperut makin sering timbul disertai demam, mual, kadang-kadang muntah bila makan, dan nafsu makan makin turun. Hasil MRI menunjukkan kesan lesi hipointens dengan tepi yang irreguler di distal CBD sepanjang ±2 cm dengan dilatasi sedang CBD di bagian proksimalnya dan dilatasi ringan IHBD serta tak tampak dilatasi pada duktus pankreatikus, mengesankan massa di distal CBD yang menyebabkan obstruksi, curiga Klatskin Tumor Type 1 (berdasarkan Bismuth Classification). Pasien menolak dilakukan tindakan pembedahan maupun kemoterapi. Pasien mengaku merasa dalam kondisi baik, keluhan nyeri perut sangat jarang, nafsu makan sudah meningkat. Kata kunci: kolangitis akut, TumorKlatskin, kolangitis
HIPERHOMOSISTEINEMIA SEBAGAI RISIKO PENYAKIT JANTUNG KORONER Astoni, Muhamad Ayus; Irawan, Bambang
Jurnal Kedokteran Brawijaya Vol 21, No 3 (2005)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (150.441 KB) | DOI: 10.21776/ub.jkb.2005.021.03.1

Abstract

The elevation of total plasma homocysteine is associated with increase of risk for cardiovascular disease, cerebrovascular disease, and atherothrombosis in peripheral arteries. Several prospective and retrospective studies had conformed the positive association between hyperhomocysteinemia and risk for cardiovascular disease. However, it whether hyperhomocysteinemia is an independent riskfactor for cardiovascular disease associated with  the others risk factors still become a question. The aim of this study was to identify the association between hyperhomocysteinemia and increased risk for cardiovascular disease. A matched case-control study based on 50 consecutive adult  patients aged more than 18 years old who admitted in Dr. SardjitoGeneral Hospital by first acute coronary syndrome.Fifty comparison control subjects were randomly selected age and gender group-matched patients admitted caused by conditions other than cardiovascular disease to the same hospital. Each case was enrolled, and comparison subject was randomly selected. Fasting blood samples for homocysteine were obtained from both groups. Chi square test, McNemar chi square test, and independent t test had been used in univariate analysis. Confounding factors had been analysed using
Kolangitis Akut pada Penderita Tumor Klatskin Astoni, Muhamad Ayus; Bardiman, Syadra; Purwoko, Mitayani
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 5 (2018): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (573.77 KB) | DOI: 10.26714/magnamed.1.5.2018.11-19

Abstract

Acute cholangitis in patients with Klatskin tumor Tumor Klatskin merupakan suatu kolangiokarsinoma tipe ekstrahepatik yang bersifat ganas dan timbul dari epitel duktus koledokus dan kedua percabangannya. Seorang wanita usia 47 tahun mengalami keluhan badan panas sejak 1 hari sebelum masuk rumah sakit. Satu hari sebelum masuk rumah sakit, pasien mengalami demam tinggi terus- menerus, tidak disertai dengan menggigil. Keluhan disertai nyeri hebat di perut kanan atas sampai ke ulu hati, nafsu makan menurun, mual setiap hendak makan, BAK berwarna seperti teh, BAB biasa, dan mata terlihat kuning. Satu minggu sebelum masuk rumah sakit, keluhan nyeri perut makin sering timbul disertai demam, mual, kadang-kadang muntah bila makan, dan nafsu makan makin turun. Hasil MRI menunjukkan kesan lesi hipointens dengan tepi yang irreguler di distal CBD sepanjang ±2 cm dengan dilatasi sedang CBD di bagian proksimalnya dan dilatasi ringan IHBD serta tak tampak dilatasi pada duktus pankreatikus, mengesankan massa di distal CBD yang menyebabkan obstruksi, curiga Klatskin Tumor Type 1 (berdasarkan Bismuth Classification). Pasien menolak dilakukan tindakan pembedahan maupun kemoterapi. Pasien mengaku merasa dalam kondisi baik, keluhan nyeri perut sangat jarang, nafsu makan sudah meningkat. Klatskin tumor is an malignant extrahepatic type of cholangiocarcinoma and arises from the choledocus ducte pithelium and its two branches. A 47-year-oldwoman has afever since one day before being hospitalized. One day before being admitted to the hospital, the patient experienced a persistent high fever, not accompanied by shivering. Complaints accompanied by severe pain in the right upper abdomen to the epigastrium, decreasedappetite, nausea, urine coloredliketea, normal bowelmovements, and eyes look yellow. One week before being hospitalized, complaintsof abdominal pain often came with fever, nausea, sometimes vomiting when eating, and appetite decreased. The MRI results showed hypointense lesions with irregular edges in the distal CBD of ±2 cm with moderate CBD dilatation in the proximal part and mild IHBD dilatation and no visible dilatation of the pancreatic ducts, impressive distal CBD mass causing obstruction, suspicious of Klatskin Tumor Type 1 (basedonBismuthClassification). Patient refused surgeryor chemotherapy. Patient claimed to feel in good condition, complaints of abdominal pain was veryrare, appetite has increased. 
THE ASSOCIATION BETWEEN BODY MASS INDEX (BMI) AND GASTROESOPHAGEAL REFLUX DISEASE (GERD) INCIDENCE AMONG VISITORS AT THE GASTROENTEROLOGY CLINIC OF RSUP DR. MOHAMMAD HOESIN PALEMBANG Zuhdi, Kgs. Muhammad; Astoni, Muhamad Ayus; Rasyid, Riana Sari Puspita; Suprianto, Imam; Prasasty, Gita Dwi
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 12 No. 2 (2025): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v12i2.626

Abstract

This study aimed to determine the association between BMI and the incidence of GERD in visitors to the Gastroclinic of RSUP Dr. Mohammad Hoesin Palembang. A total of 153 samples met the eligibility requirements, this study used a random sampling technique and collected primary data through a questionnaire instrument. Data were analyzed using SPSS Statistic V27 in univariate, bivariate (chi-square test) and multivariate (logistic regression enter method) analysis. The majority of GERD patients were aged 36-65 years (46.7%), male sex (46.2%) and BMI in the obese category (65.9%). The results of this research showed no significant association among age and sex in the incidence of GERD, but there was a significant association between BMI on the incidence of GERD (p=0.003) thus being the most significant variable in this research (p=0.012). In conclusion, there is a significant association between BMI and the incidence of GERD while there is no significant association among age and sex in the incidence of GERD.