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All Journal Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Sciences) Jurnal Kedokteran Hewan
Yendri, Hamdika
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Immunology & microbiology Medicine & Pharmacology Veterinary

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THE EFFICACY OF AVOCADO, MUNG BEAN SPROUTS, AND HOLY BASIL HERB COMBINATION (JAMU ATOKE) ON THE HEALTH AND REPRODUCTIVITY OF ADULT FEMALE RATS Andriyanto, Andriyanto Andriyanto; Widi, Leliana Nugrahaning; Yendri, Hamdika; Mardathilah, Kharisma; Yuliansah, Diky; Agustin, Firda; Mustika, Aulia Andi; Manalu, Wasmen
Jurnal Kedokteran Hewan Vol 16, No 4 (2022): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v16i4.24037

Abstract

The purpose of this study was to examine the efficacy of a herbal combination of avocado, mung bean sprouts, and holy basil (Jamu ATOKE) in optimizing the reproductive health of adult female rats. Eighteen female Sprague Dawley rats aged 9-10 weeks old weighing around 180-250 g, and had not been pregnant previously were equally and randomly divided into 3 groups: one control group and two treatment groups (n= 6 rats per group). The treatment groups received Jamu ATOKE with a concentration of 2.5 and 5%, respectively. Jamu ATOKE was added to the drinking water and consumed by the rats for 30 days prior to pregnancy. Reproductivity (pregnancy success, estrogen and progesterone hormone concentrations), and health performance (body weight gain, food, and water consumption, motor activity, red blood cell (RBC) count, white blood cell (WBC) count and differentials, SGPT, SGOT, ureum, and creatinine) of rats were observed. The results showed that groups receiving the Jamu ATOKE had better reproductive and health performance compared to those of the control group. The administration of Jamu ATOKE can significantly increase the concentration of estrogen and progesterone in rats (P0.05). It can also improve the fertility and health of the female rats prior to pregnancy.
Analisis potensi hepatoprotektif minyak jintan hitam (Nigella sativa) pada kerusakan hati akibat paracetamol: Potential analysis of black cumin oil hepatoprotective (Nigella sativa) on liver damage due to paracetamol Yendri, Hamdika; Andriyanto, Andriyanto; Mustika, Aulia A.; Manalu, Wasmen; Subangkit, Mawar; Tarigan, Elpita
Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Science) Vol. 14 No. 1 (2024): Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Ve
Publisher : Fakultas Peternakan Universitas Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46549/jipvet.v14i1.353

Abstract

Abstract  A decrease in liver function can cause some clinical impact on the body. The loss of the body's ability to metabolize toxins makes metabolic remains accumulate in the blood.  This study aims to determine the potential of black cumin oil hepatoprotective. This study used 25 ddY mice. Mice were given black cumin oil for 20 days and inducted liver cell damage using paracetamol dose 300mg/KgBB. Results showed the potential of black cumin oil hepatoprotective in the group given 60μL of black cumin oil. These results were obtained from the measurement of SGPT, SGOT values and histopathological observations of the liver organs of mice. These results show that black cumin preparations are able to suppress liver damage due to paracetamol. Keywords: Black cumin; Liver; Paracetamol   Abstrak  Penurunan fungsi hati dapat menyebabkan beberapa dampak klinis pada tubuh. Kehilangan kemampuan tubuh untuk memetabolisme racun menjadikan sisa-sisa metabolisme menumpuk di dalam darah. Penelitian ini bertujuan untuk mengetahui potensi hepatoprotektif minyak jintan hitam. Penelitian ini menggunakan mencit ddY berjumlah 25 ekor. Mencit diberikan minyak jintan hitam selama 20 hari dan dilakukan induksi kerusakan sel hati menggunakan paracetamol dosis 300mg/KgBB. Hasil penelitian menunjukan adanya potensi hepatoprotektor minyak jintan hitam pada kelompok yang diberikan 60µL minyak jintan hitam. Hasil ini didapatkan dari pengukuran nilai SGPT, SGOT dan pengamatan histopatologi organ hati mencit. Hasil ini menunjukan sediaan jintan hitam mampu menekan kerusakan hati akibat paracetamol. Kata kunci: Hati; Jintan hitam; Paracetamol
Co-Authors Andriyanto Andriyanto Andriyanto, Andriyanto Andriyanto Aulia Andi Mustika Elpita Tarigan Firda Agustin, Firda Mardathilah, Kharisma Mustika, Aulia A. Subangkit, Mawar Wasmen Manalu Widi, Leliana Nugrahaning Yuliansah, Diky