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All Journal Jurnal Ilmu Pertanian Indonesia Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Cancer Chemoprevention Jurnal Berkala Epidemiologi Majalah Obat Tradisional JURNAL PENGABDIAN KEPADA MASYARAKAT Journal of Tropical Biodiversity and Biotechnology Jurnal Farmasi Sains dan Komunitas International Journal of Science and Applied Science: Conference Series ALCHEMY Jurnal Penelitian Kimia Jurnal Pengabdian Pada Masyarakat JPSCR : Journal of Pharmaceutical Science and Clinical Research PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Kreativitas PKM JKPK (Jurnal Kimia dan Pendidikan Kimia) Bubungan Tinggi: Jurnal Pengabdian Masyarakat Borneo Journal Of Pharmascientech Biodiversitas Journal of Biological Diversity

Heru Sasongko

Department Of Pharmacy, Faculty Of Mathematics And Natural Sciences, Universitas Sebelas Maret

Author-ID : 845287

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Pengaruh penambahan sukrosa terhadap mutu sabun transparan dari ekstrak etanol herba pegagan (Centella asiatica L.) Sasongko, Heru; Mumpuni, Andarini Siwi
Pharmaciana Vol 7, No 1 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Centella asiatica is a kind of herbs which contains antioxidant that be trusted to overcome of various skin problems such as keloids, cellulite, and black stains. One of the additional ingredients used to make the transparent soap is sucrose or frequently called white sugar. In the process of making the transparent soap, white sugar is served to help the transparency of soap. The purpose of this research is to find out the effect of increasing the sucrose toward the degree of the transparency of the soap, stability of physical properties before and after storage for eight weeks and find out the skin response towards the soap by doing irritability test towards some respondents. Pegagan extract transparent soap is varied with the concentration of sucrose 11 %, 13%, and 15 %. The soap which is produced is conducted with a series of tests of physical characteristics include transparency, pH, water content, and the stability of the foam. The results showed that the addition of sucrose affects the level of transparency and soapy water levels and no effect on pH and foam stability. Irritation test of the respondents showed most respondents did not become irritated. The stability of the physical characteristic of the form of the soap is good because during eight weeks of the usage there are no significant

In-Vivo Analgesic And Anti-Inflammatory Effects Of Eel (Anguilla bicolor bicolor) Oil Heru Sasongko; Nur Indria Kusumastuti; Gea Ros Alifa; Aulia Ayu Rahmawati
Pharmaciana Vol 9, No 1 (2019): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Analgesic and anti-inflammatory tests of eel (Anguilla bicolor bicolor) oil on animal models have been performed. Previous studies have proven that oral administration of EPA and DHA exhibits analgesic and anti-inflammatory effects. Gas Chromatography analysis shows that eel contains EPA and DHA. In this research, the analgesic activity was evaluated with the acetic acid-induced writhing test and hot plate test, while the anti-inflammatory properties were identified using carrageenan-induced inflammation. In the writhing test, 25 male Swiss Webster mice were divided into five groups. Group I was given 0.5% CMC-Na as a negative control, group II was given 65 mg/kg b.w. of Acetosal as a positive control, group III-V was given eel oil at different doses, namely 2400, 4800, and 9600 mg/kg b.w. of the mouse. For the hot plate test, 6.5 mg/kg b.w. of tramadol acted as the positive control. Similar to the analgesic effect analysis, the anti-inflammatory test also divided 25 male Wistar rats into five groups. Group I as a negative control was given 0.5% CMC-Na, Â group II was given 9 mg/kg b.w. of diclofenac potassium as a positive control, and group III-V were given eel oil at different doses, namely 1500, 3000, and 6000 mg/kg b.w. of the rat. The results of the acetic acid-induced writhing test and hot plate test showed that when compared with the positive and negative controls, eel oil had a potential analgesic activity with a significance value of p< 0.05. The analgesic effects were noticeable at doses of 2400, 4800 and 9600 mg/kg b.w. in the writhing test and at 4800 and 9600 mg/kg b.w. in the hot plate test. The anti-inflammatory test showed that eel oil was efficacious when administered at the doses of 1500, 3000, and 6000 mg/kg b.w. with percentage inhibition of 34.35%, 35.132%, and 40.28%, respectively.Â

Pengaruh penambahan sukrosa terhadap mutu sabun transparan dari ekstrak etanol herba pegagan (Centella asiatica L.) Heru Sasongko; Andarini Siwi Mumpuni
Pharmaciana Vol 7, No 1 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Cox-2 inhibition activities of creams containing anguilla bicolor and sea cucumbers extract on croton oil induced inflammation in mice Heru Sasongko; Waliyyin Razan Qanit; Raka Sukmabayu W.S; Agung Putu S.P.Kristyawan; Nining Sugihartini; Wisnu Kundarto; Dian Eka Ermawati
Pharmaciana Vol 10, No 3 (2020): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The fatty acids, like EPA and DHA, were known as anti-inflammation. It works on inflammatory tissue, brought by edema plasma, and changed into resolvins, protectins, and maresins by the enzyme reaction. Anguilla bicolor and Sea cucumber fish are known to contain EPA and DHA. This study analyzes the inhibition Cox-2 effect of the combination of Anguilla bicolor oil with Sea cucumber extract as an active ingredient in a cream preparation. This experiment used 7 groups of male BALB/C strain mice: normal control; negative control; positive control; A. bicolor oil cream; H. leucospilota extract cream; a combination of A. bicolor : H. leucospilota (2:1) cream; a combination of A. bicolor : H. leucospilota (1:2) cream. The anti-inflammatory activity was evaluated by the amount of inflammatory cell, the thickness epidermis, and the amount of cell expression COX-2Â on mice's back skin tissue induced by croton oil (0,1 %). After 3 days, histopathological skin tissues were made. The data were analyzed statistically by One Way ANOVA followed by LSD to know each group's differences at a significance level of 0.05. The experiment results showed that the formula with the best anti-inflammatory activities is the combination of A. bicolor and H. leucospilota (2:1) cream.Â The decrease of the amount of inflammatory cell (75.97%), the thickness of the epidermis (43.88%), and the amount of COX-2 cell expressions (60.52%) from the formula did not differ significantly with the positive control (p>0,05). It can be concluded that A. bicolor and H. leucospilota have anti-inflammation activity based on the experiment results.

In-vitro and In-vivo Determinations of Sun Protection Factors (SPF) of Skin Lotions Containing Mountain Papaya Fruit and Mangosteen Peel Ethanolic Extract Heru Sasongko; Natasya Advaita; Ratih Guswinda Lestari; Karimah Umar Aidid
Majalah Obat Tradisional Vol 25, No 3 (2020)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.49931

Indonesia is a high sun exposure country. Exposure to ultraviolet (UV) causes various kinds of skin disorders such as erythema, sunburn, aging, and cancer. Mountain papaya fruit (Vasconcellea pubescens A.DC.) and mangosteen peel (Garcinia mangostana L.) contains metabolite compounds that can protect the skin from sunlight because of its antioxidants activity. The purpose of this study to determine whether the combination of the mountain papaya fruit and mangosteen peel extracts in skin lotion can be used as sun protectors through the in-vitro and in-vivo study. The experiment was done by extracting the mountain papaya fruit and mangosteen peel through the maceration method. The extracts were formulated into skin lotion in three different formulas with the ratio of mountain papaya fruit extract: mangosteen peel extract as follows F1(1:1), F2(1:3), and F3(3:1). In vitro test was done by using UV-VIS spectrophotometry to determine the SPF value and in vivo test was used erythema-induced rats by exotera beam light. The result of in vitro test gained a high enough SPF value for all three formulas F1=23,23; F2=21,70 and F3=28,64 and the result of in vivo test showed that all three formulas did not indicate the existence of erythema value. It can be concluded that three skin lotion formulas containing mountain papaya fruit and mangosteen peel ethanol extract have the effect of sun protection.

Supplementation of Garcinia mangostana Linn and Vasconcellea pubescens A.DC extract reduced exercise-induced oxidative stress in rats Heru Sasongko; Sugiyarto Sugiyarto; Renita Wahyu Nur Hidayati; Bayu Anggoro Saputro
Majalah Obat Tradisional Vol 26, No 3 (2021)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.68517

The objective of this study was to see how supplementation with Garcinia mangostana extract (GME) and Vasconcellea pubescens extract (VPE) affected exercise performance and oxidative stress in intensely exercised rats. Twenty-five male rats were used in the study. Rats were divided into five groups: normal, stress oxidative control, combination GME:VPE (50:50), combination GME:VPE (75:25), and combination GME:VPE (25:75) groups. The antioxidant activity of a single extract from the literature was used to make the percentage comparison between extracts. The chronic exercise was done by swimming at 10 m/day for two weeks. Rats in the acute exercise groups were treated by swimming on the pail containing water. Blood samples were collected from the orbital sinus to determine hematological parameters. Liver tissue samples for the analysis of malondialdehyde (MDA) and glutathione (GPx) markers. Data analysis was performed statistically using One Way ANOVA. The combination of GME and VPE was shown to be effective in reducing oxidative stress and increasing MDA and GPx enzyme activity. The administration of both extracts also showed changes in the hematological profile.

ANALISIS KANDUNGAN NUTRISI PADA PAKAN DENGAN FEED ADDITIVE RESIDU EKSTRAKSI KULIT MANGGIS (Garcinia Mangostana L.) Heru Sasongko; Yeni Farida; Nur Indriana Kusumastuti; Gea Ros Alifa; Sutanto Sutanto
JURNAL PENGABDIAN KEPADA MASYARAKAT Vol 23, No 1 (2017): JANUARI - MARET
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpkm.v23i1.6631

AbstrakUsaha peternakan merupakan salah satu sektor penyokong perekonomian Indonesia. Dalam menjalankan usaha peternakan dibutuhkan pakan yang berkualitas sehingga dihasilkan ternak yang berkualitas pula. Sekitar 70-80% dari biaya total untuk pengelolaan peternakan dibutuhkan untuk pakan, sehingga perlu adanya inovasi untuk memformulasikan pakan sehingga mampu menekan biaya yang dibutuhkan peternak dan meningkatkan pendapatan. Tujuan dari penelitian ini adalah memperoleh pakan yang diformulasikan dengan ampas ekstraksi dengan sifat fisik yang memenuhi standar dan kandungan nutrisi yang sesuai. Hasil yang diperoleh menunjukan bahwa pakan masih memiliki kelembaban yang tinggi, akan tetapi memiliki kandungan energi total dan protein yang tinggi.Kata Kunci : residu, kulit manggis, feed additive, pakan, kandungan nutrisi Abstract Farm is one of the supporting sectors of the Indonesian economy. In carrying out farm, quality feed required to produce quality livestock. Approximately 70-80% of the total cost required to feed livestock management, so the need for innovation to formulate feed so as to reduce the cost required farmers and increase revenue. The outcome of this study was to obtain formulated feed with the residual extraction of Garcinia mangostana L with physical properties that meet the standards and nutrient content accordingly. The results showed that feed still has a high humidity, but has a total high total energy and proteinKeywords: feed additive, nutrition content, mangosteen

Menjaga Kualitas Jamu Kunyit Asam Segar Industri Rumah Tangga X Yogyakarta dengan Penyimpanan Suhu yang Tepat Berdasarkan Kadar Kurkuminoid Dian Eka Ermawati; Villian Septiana; Wisnu Kundarto; Anif Nur Artanti; Sholichah Rohmani; Heru Sasongko
Jurnal Pengabdian Pada Masyarakat Vol 6 No 2 (2021)
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/002.202162.617

IMPROVING THE QUALITY OF FRESH ACID TURMERIC JAMU OF HOME INDUSTRY X AT THE RIGHT TEMPERATURE STORAGE BASED ON CURCUMINOID CONCENTRATION. Tamarind turmeric herbal medicine contains about 10% curcuminoids, consisting of: 1-5% curcumin, demectosicurcumin and bisdemethoxy-curcumin. Curcuminoids are a group of phenolic compounds as antibacterial, anticholesterol and antioxidants. Home Industry (IRT) X in Yogyakarta produces fresh turmeric and sour herbal medicine and is sold via delivery via an online application. Handling and storage at inappropriate temperatures can affect curcuminoid levels in herbal medicine, so it is necessary to do research on curcuminoid levels at various temperatures to provide information on IRT X in particular and herbal medicine manufacturers in general. Samples of herbal turmeric acid IRT X Yogyakarta stored at room temperature (25±2°C), refrigerator temperature (4±2°C), and freezer temperature (-10±2°C), analyzed the levels of curcuminoids on variations in storage temperature manually. quantitative method with UV-Vis Spectrophotometry. The analysis begins with the manufacture of standard curves and assays which are replicated three times. The results showed that curcuminoid levels were affected by storage temperature. Samples of herbal turmeric acid IRT X Yogyakarta which were analyzed by UV-Vis spectrophotometry method obtained a standard curve of y = 0.009x + 0.025 with a value of r = 0.997. The results of curcuminoid levels at room temperature were 4.74±0.13; refrigerator temperature 4.85±0.22; and freezer temperature 5.18±0.22. The optimum temperature in the handling and storage of the tamarind turmeric herbal medicine is at low temperatures, namely the refrigerator temperature and freezer temperature to maintain the curcuminoid content in the herbal medicine.

PENILAIAN POLA PENGGUNAAN OBAT BERDASARKAN INDIKATOR PERESEPAN WHO DI RSUD Ir SOEKARNO SUKOHARJO Pujaningsih Pebriana; Pratiwi Hening Puspitaningtyas; Heru Sasongko
BORNEO JOURNAL OF PHARMASCIENTECH Vol 2 No 1 (2018): Borneo Journal of Pharmascientech
Publisher : Sekolah Tinggi Ilmu Kesehatan Borneo Lestari Banjarbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar

PENILAIAN POLA PENGGUNAAN OBAT BERDASARKAN INDIKATOR PERESEPAN WHO DI RSUD Ir SOEKARNO SUKOHARJO ASSESSMENT OF DRUG USAGE PATTERN BASED ON THE PRESCRIPTION INDICATOR IN THE RSUD Ir SOEKARNO SUKOHARJO Pujaningsih Pebriana, Pratiwi Hening Puspitaningtyas, Heru Sasongko* Prodi D3 Farmasi, FMIPA Universitas Sebelas Maret Jl. Ir. Sutami 36 A, Kentingan Surakarta 57126 Jawa Tengah * herusasongkoapt@gmail.com ABSTRAK Penggunaan obat yang rasional merupakan bagian terpenting dalam system pelayanan kesehatan. WHO sebagai organisasi kesehatan terbesar di dunia telah mengembangkan indicator penggunaan obat yang rasional. Rumah Sakit merupakan salah satu fasilitas pelayanan kesehatan yang berperan dalam peningkatan upaya kesehatan bagi masysrakat. Tujuan dari penelitian ini adalah mengidentifikasi kesesuaian penggunaan obat pada pasien berdasarkan indicator yang telah ditetapkan oleh WHO. Studi dilakukan secara deskriptif observasional di instalasi farmasi rawat jalan RSUD Ir. Soekarno Sukoharjo. Sampel diambil dari lembar resep pasien umum rawat jalan bulan Januari – Desember 2013 secara retrospektif sebanyak 600 lembar resep dengan teknik cluster proportional random sampling. Data yang diperoleh dianalisis berdasarkan lima variabel penelitian, yaitu persentase kesesuaian peresepan dengan formularium rumah sakit, rata-rata jumlah item obat per lembar resep, persentase peresepan obat dengan nama generik, persentase peresepan sediaan injeksi dan persentase peresepan antibiotik. Hasil penilaian adalah kesesuaian peresepan dengan formularium rumah sakit 92,47%; rata-rata item obat tiap lembar resep sebesar 2,46; peresepan dengan nama generik 52,83%; peresepan antibiotik 18,08% dan penggunaan sedian injeksi sebesar 0% Kata kunci : penggunaan obat, indikator peresepan, rasional, WHO

Pelatihan Pemanfaatan Minyak Atsiri sebagai Bahan Aktif Balsam Aromaterapi kepada Warga Kelurahan Mojosongo M Fiqri Zulpadly; Dian Eka Ermawati; Heru Sasongko; Anif Nur Artanti; Sholichah Rohmani; Wisnu Kundarto; Diyah Tri Utami
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 4, No 4 (2022)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v4i4.6684

Pandemi Covid-19 yang melanda hampir seluruh negara di dunia khususnya di Indonesia membuat banyak masyarakat cemas, stres, dan frustasi akibat ketidakpastian dari berbagai aspek kehidupan. Stres pada umumnya merupakan kondisi normal dan tidak menimbulkan masalah pada kesehatan. Balsam aromaterapi dengan bahan utama dari minyak atsiri dapat digunakan sebagai alternatif untuk dapat merelaksasikan tubuh serta berperan dalam pengaturan emosional. Pengabdian kepada masyarakat ini adalah transfer pengetahuan dan pendampingan pelatihan pembuatan balsam aromaterapi. Kegiatan yang dilakukan mencakup pemberian informasi terkait pembuatan balsam yang dilanjutkan dengan demo pelatihan pembuatan balsam aromaterapi. Kegiatan pengabdian yang dilaksanakan pada tanggal 25 Oktober 2022 menghasilkan sebuah produk balsam aromaterapi hasil karya tangan para warga yang turut hadir yang didampingi oleh tim dari D3 Farmasi UNS. Kegiatan ini telah mencapai sasaran yang diinginkan yaitu kemampuan warga Kelurahan Mojosongo dalam membuat suatu produk skala kecil menengah namun memiliki nilai yang tinggi baik dari aspek guna maupun finansial. Kegiatan pendampingan ini merupakan langkah awal dalam membentuk kemandirian masyarakat setempat untuk memproduksi balsam aromaterapi secara mandiri ataupun kelompok yang berada dalam lingkup UMKM.The Covid-19 pandemic that hit almost all countries, especially in Indonesia, made many people anxious, stressed, and frustrated due to the uncertainty of various aspects of life. Stress is generally a normal condition and does not cause health problems. Aromatherapy balms with the main ingredients of essential oils can be used as an alternative to relax the body and play a role in emotional regulation. This community service is the transfer of knowledge and assistance in training on making aromatherapy balm. The activities included providing information on making balm, followed by a training demonstration on aromatherapy balm. The service activity, carried out on October 25, 2022, resulted in an aromatherapy balm product that was handmade by the present residents, accompanied by a team from UNS Pharmacy D3. This activity has achieved the desired target, namely the ability of the residents of Mojosongo Village to make a small-medium-scale product that has a high value both in terms of use and finances. This mentoring activity is the first step in establishing the independence of the local community to produce aromatherapy balm independently or in groups within the scope of Micro Small and Medium Enterprises (MSME).

Co-Authors Aan Andri Yano Adistyara Nur Faizah Agung Budiharjo Agung Putu S.P.Kristyawan Ahmad Dwi Setyawan Andarini Siwi Mumpuni Anif Nur Artanti Anif Nur Artanti Anif Nur Artanti Anif Nur Artanti Anif Nur Artanti Anif Nur Artanti, Anif Nur Anis Laela Megasari Annisa Diyan Meitasari Annisa Diyan Meitasari Arinda Handiyah Sawitri Aulia Ayu Rahmawati Aulia Ayu Rahmawati Aulia Hanundita Maharani Bayu Anggoro Saputro Bayu Anggoro Saputro Delia Putri Hedianti Delia Putri Hedianti Diah Pratiwi Dian Eka Ermawati Dian Eka Ermawati Dian Eka Ermawati Dian Eka Ermawati Dian Eka Ermawati Diyah Tri Utami Diyah Tri Utami Diyah Tri Utami Diyah Tri Utami Diyah Tri Utami Diyah Tri Utami ERMAWATI, DIAN EKA Feri Setyawan Fiddin Yusfida A’la Gea Ros Alifa Gea Ros Alifa Hanif Maulana Tomera Hanum Kartikasari HASBIYAN ROSYADI Herliana Riska Ika Subekti Wulandari Jevi Ramadhan Berliani Jihan Nabila Josua Arianto Hutasoit Karimah Umar Aidid Lathyfa Asyraq Listiyana Ika Safitri Listiyana Ika Safitri Lois Elda Zai M Fiqri Zulpadly M Fiqri Zulpadly M. Fiqri Zulpadly M. Fiqri Zulpadly M. Fiqri Zulpadly M. Fiqri Zulpadly M. Fiqry Zulpadly M H MEI RATNASARI Meta Kartika Untari Meta Kartika Untari Meta Kartika Untari Meta Kartika Untari Meta Kartika Untari Mikael Hovhanness Muhamad Reznu Firsyawardana Muhammad Fiqri Zulpadly Muhammad Fiqri Zulpadly Muhammad Fiqri Zulpadly Mahmud Mumpuni, Andarini Siwi Naswya Sausan Aqila Sausan Natasya Advaita Nindita Claurisa Amaris Susanto Nindita Clourisa Amaris Susanto Nindita Clourisa Amaris Susanto Nindita Clourisa Amaris Susanto Nindita Clourisa Amaris Susanto Nindita Clourisa Amaris Susanto Nindita Clourisa Amaris Susanto Nining Sugihartini Novi Ria Rahmawati Nur Cahyo Fajar Trihantono Nur Indria Kusumastuti Nur Indriana Kusumastuti Nur Rohman Efendi Nur Rohman Efendi Okky Mareta Octadevi Pratiwi Hening Puspitaningtyas Pujaningsih Pebriana Putri Cahaya Situmorang Raka Sukmabayu W.S Ratih Guswinda Lestari Ratih Guswinda Lestari Renita Wahyu Nur Hidayati Renita Wahyu Nur Hidayati Rika Dwi Indasari Rindy Fidestia Anjaini Risky Diah Wulandari SAFIRA CHAIRUNISA Salistia Musta’ani Sholichah Rochmani Sholichah Rohmani Sholichah Rohmani Sholichah Rohmani Sholichah Rohmani Sholichah Rohmani Sholichah Rohmani SITI GIA SYAUQIYAH FITRI Sugiyarto Sugiyarto Sugiyarto Sugiyarto Sugiyarto Sugiyarto Sugiyarto Sugiyarto Sugiyarto Sugiyarto Sutanto Sutanto SUTARNO SUTARNO Sutarno Sutarno Tetri Widiyani Ulfa Afrinurfadhilah Darojati Ulfa Afrinurfadhilah Darojati Villian Septiana Vivin Sulistyowati Waliyyin Razan Qanit Wisnu Kundarto Wisnu Kundarto Yavi Hanuriansyah Yeni Farida Yeni Farida Yeni Farida Yumna Zulfa Salsabila

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