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All Journal Jurnal Keperawatan Indonesia Journal of Health (JoH) Belitung Nursing Journal Media Ilmu Kesehatan Jurnal Kesehatan Karya Husada I Care : Jurnal Keperawatan STIKes Panti Rapih Jurnal Ilmiah Kesehatan Sandi Husada (JIKSH)
Chatarina Setya Widyastuti
Stikes Panti Rapih Yogyakarta
Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Effect of virgin coconut oil on total cholesterol levels in patients with hypercholesterolemia: A quasi-experimental study Fransisca Anjar Rina Setyani; Chatarina Setya Widyastuti; Hiasinta Anastasia Purnawijayanti
Jurnal Ilmiah Kesehatan Sandi Husada Vol. 15 No. 2 (2026): Articles in Press
Publisher : LPPM Politeknik Sandi Karsa, South Sulawesi, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiksh.v15i2.394

Abstract

Introduction: Hypercholesterolemia is closely associated with increased cardiovascular risk and is influenced by unhealthy dietary patterns, aging, obesity, and limited physical activity. Virgin coconut oil (VCO) has been widely introduced as a complementary nutritional therapy because it contains medium-chain fatty acids, polyphenols, and antioxidant compounds that may improve lipid metabolism. Nevertheless, findings regarding its effectiveness in reducing cholesterol levels remain inconsistent. This study aimed to analyze the effect of VCO administration on total cholesterol levels among patients with hypercholesterolemia in Padukuhan Tegalsari, Pakembinangun, Yogyakarta. Research Methodology: This study employed a quasi-experimental pre–post test design with a control group approach. A total of 66 respondents with total cholesterol levels >180 mg/dL were selected using purposive sampling and were equally allocated to the intervention (n=33) and control (n=33) groups. The intervention group received VCO at a dose of 2 × 20 mL daily for 14 consecutive days, while the control group received no intervention. Total cholesterol levels were measured using peripheral blood samples before and after the intervention period. Data were analyzed using the Mann–Whitney test with a significance level of 0.05. Results: Most respondents were elderly (89.4%) and female (59.1%). Risk-related behaviours remained common, including daily consumption of fried foods (46.96%) and low physical activity (<3 times/week; 46.96%). Before treatment, both groups showed comparable cholesterol levels (p=0.326), with most respondents classified in the very high cholesterol category. After the intervention, the proportion of respondents in the very high cholesterol category increased from 63.8% to 84.8% in the intervention group. Statistical analysis demonstrated no significant difference in total cholesterol levels between the intervention and control groups after treatment (p=0.200). Conclusion: Administration of VCO at a dose of 2 × 20 mL for 14 days did not significantly reduce total cholesterol levels in patients with hypercholesterolemia. Lipid profile management requires a comprehensive approach that takes various risk factors into account. The limitations of this study include the relatively short duration of the intervention (14 days) and the fact that a complete lipid profile assessment was not carried out. Future studies are recommended to employ a longer intervention period and to evaluate lipid profiles comprehensively, including HDL, LDL and total cholesterol.
Co-Authors Bramasta, Andika Deviana Widayanti Eva Marti Hening Pujasari Hiasinta Anastasia Purnawijayanti Irawati Hardjono, Ganes Katarina Vita Wahyu Kristiani Khudazi Aulawi Lucia Kris Dinarti Lutfan Lazuardi Maura Hardjanti , Sr. Therese Nugraheni, Hilaria Asri Prabandari, Anna Pujiastuti, Tatik Ratna Sitorus Ratnawati, Emmelia Reyaan, Hendrikus Setyani, Fransisca Anjar Rina Suryanta Nugraha, Antonius Tatik Pujiastuti Widyastanti, Christina Restu Wungo, Jefry Ade Yulia Wardani