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All Journal Majalah Kedokteran Bandung Pharmaciana: Jurnal Kefarmasian Biomedical Engineering Majalah Obat Tradisional
Wahyu Widowati
Faculty of Medicine, Maranatha Christian University, Bandung, West Java, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Journal : Biomedical Engineering

 1 
Antioxidant properties of spice extracts Wahyu Widowati; Hana Ratnawati; Winsa Husin; Maesaroh Maesaroh
Biomedical Engineering Vol 1, No 1 (2014)
Publisher : Biomedical Engineering

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Abstract

Objective : This study was conducted to determine the antioxidant activities of spice extracts including clove (Syzygum aromaticum L.), Indonesian cassia (Cinnamomum burmanni (C. Nees& T. Ness)), coriander (Coriandrum sativum L), nutmeg (Myristica fragrans Houtt), java cardamom (Amomum compactum Soland. Ex maton). Methods : This research was to evaluate antioxidant activities including 1,1-diphenyl-2picryl-hydrazyl (DPPH) scavenging activity, the value of superoxide dismutase (SOD), and total phenolic content. Results : The highest DPPH activity is clove and Indonesian cassia extracts with IC value 4.16 μg/ml and 5.46 μg/ml respectively. The highest SOD value are Indonesian cassia extract (9.1432 U/ml) at 500 µg/ml, 7.0045 U/ml at 125 µg/ml and 4.6751 U/ml at 31,25 µg/ml. Clove extract was the highest of phenolic content  (188.35 µg/mg eugenol equivalent). Conclusion : Indonesian cassia extract have high antioxidant activities. Clove extract contain the highest eugenol compared with Indonesian cassia, coriander, nutmeg and java cardamom.  Key Words: antioxidant; free radicals; spice; total phenolic content
Phytochemical assay, potential of antimalarial and antioxidant activities of green tea extract and its fractions Fanny Rahardja; Rita Tjokropranoto; Wahyu Widowati; Siska Lusiana; Adrian Suhendra; Susy Tjahjani; Iwan Budiman; Maesaroh Maesaroh; Nurul Fauziah
Biomedical Engineering Vol 1, No 1 (2014)
Publisher : Biomedical Engineering

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Abstract

Objective : The research objective was to evaluate the phytochemical compounds, the antioxidant and anti-malarial activity of green tea extract and its fraction. Methods: The antioxidant activity were measured by 1,1-diphenyl-2-picryl-hydrazyl (DPPH) scavenging activity used in vitro laboratories prospective experimental design and completely randomized design, using ethanol extract, hexane, ethyl acetate, butanol fraction, and water fraction ofgreen tea in 7 levels of concentration compared to epicatechin (EC). The data were analyzed using linear regression analysis, and were continued by determined Inhibitory Concentration). The anti-malarial activity of green tea fractions were compared to artemisinin. The data were analyzed using probit analysis, and were continued by determined IC. Results: The results showed that the highest antioxidant activity (IC50) was the fraction of ethyl acetate 2,184 µg/ml. The anti-malarial activity IC50 50 of water and ethyl acetate fraction, ethanol extract and butanol fraction were 0,000090 µg/mL,0,003 µg/mL, 0,006 µg/mL, 0,011 µg/ml respectively.Conclusion: Extract and fractions of green tea have potential anti-malarial and antioxidant properties. Key Words: antioxidant; anti-malarial; green tea; free radicals
Co-Authors Adek Armansyah Adrian Suhendra Annisa Amalia Buter Samin Buter Samin Chrismis Novalinda Ginting Chrismis Novalinda Ginting Edy Fachrial Ermi Girsang Ermi Girsang Fanny Rahardja Geeta Geeta HANA RATNAWATI Hendy Million I Nyoman Ehrich Lister I Nyoman Ehrich Lister I Nyoman Ehrich Lister Ika Adhani Sholihah Iwan Budiman Liena Liena Lisma Viany Lister Ehrich I Nyoman Maesaroh Maesaroh Maesaroh Maesaroh Martinus Ahmad Raif Nurul Fauziah Rita Kusuma Rita Tjokropranoto Rizal Rizal Sidharta Kunardi Siska Lusiana Susy Tjahjani Tandiah Asan Wahyu Setia Widodo Winsa Husin