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Effect of Propolis on the Adhesion Index, Morphology and Viability of Candida albicans Cells on Biofilm Formation Dinda Oktia Maghfiroh; A.A. Santi Dewi; Anggie Diniayuningrum; Bambang Rahardjo; Nurdiana Nurdiana; Agustina Tri Endharti; Sumarno Sumarno
Medical Laboratory Technology Journal Vol. 7 No. 1 (2021): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Approximately 70-75% of reproductive women have experienced vulvovaginal candidiasis at least once, and 40-45% will have recurrences. Candida albicans is the most etiology of vulvovaginal candidiasis and is able to form a biofilm that can lead to antifungal resistances and recurrences. One of the natural products that have an anti biofilm effect is propolis. This study expected that propolis from Lawang can be one of the anti-biofilm agent candidates for antifungal resistant cases. This study aimed to know the anti-biofilm effect of propolis ethanol extract on cell adhesion index, morphology, and viability of Candida albicans cell on biofilm formation. The adhesion index was counted on 100 epithelial cells under light microscopy (1000x). Morphology was seen using light microscopy (400x). Cell viability was examined by CFU assay. At 12.5% concentration of propolis ethanol extract, adhesion index decreased (p=0,000), and hyphal growth was inhibited. Colony growth decreased at 2.5% concentration and was not seen at 10% concentration of propolis ethanol extract (p=0,000). These results indicated that propolis ethanol extract could decrease adhesion index, failed the Candida albicans morphology transition from yeast to hyphal, and decreased Candida albicans cell viability on biofilm formation. Propolis ethanol extract is likely to be one of the alternatives to recurrent vulvovaginal candidiasis treatment, especially caused by Candida albicans biofilm formation.

PENDAMPINGAN PENYUSUNAN SATGAS PENCEGAHAN DAN PENANGANAN KEKERASAN SEKSUAL (PPKS) Yuniar Angelia Puspadewi; Jiarti Kusbandiyah; Dinda Oktia Maghfiroh
Media Husada Journal Of Community Service Vol. 4 No. 2 (2025): Media Husada Journal of Community Service
Publisher : STIKES Widyagama Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/mhjcs.v4i2.56

Any form of action that causes someone to feel insulted, harassed, humiliated and experience violence related to reproductive function, causing physical or psychological suffering and disrupting reproductive health is a resolution of sexual violence, the incidence of which is increasing from year to year. During the period of 2023, the Ministry of Women's Empowerment and Child Protection recorded 19,593 cases of violence in Indonesia. Women are more at risk of experiencing sexual violence than men with a percentage of 88.5%. Adolescents in the 13-17 age range are also a larger group experiencing violence by 38% compared to the 6-12 age group, 18-24 years and under 5 years of age. Physical violence is more common when compared to psychological violence, which is 43.8%.. This indicates that junior and senior high school age teenagers are the most victims of sexual violence. The number of cases of sexual violence in Malang Regency ranks first in East Java. In 2021 there were 125 cases reported and in 2022 up to July there will have been 135 cases, so it is estimated that this will increase by 50-100%. The number of sexual violence recorded is a reported incident, however, there are many cases that are not officially reported, which are called dark numbers, which have the potential to be higher than what is reported. This is due to the reluctance of victims to report due to the following factors: 1). Feelings of shame over the incident experienced because they are often blamed for the incident; 2). Unclear mechanisms regarding reporting cases of sexual violence; 3). Victims' distrust of the existing treatment system; 4). Not realizing that the incident was an act of sexual violence and 5). Fear of the risks that will be faced if the case is reported.

Relationship Between Body Image Perception, Eating Habits and Hemoglobin Levels among Adolescent Girls : A Cross-Sectional Study Sabatina Windyaningrum; Dinda Oktia Maghfiroh; Naila Farihatul Itsnainy; Dellis Eka Mutiasari
Oksitosin : Jurnal Ilmiah Kebidanan Vol. 13 No. 1 (2026): OKSITOSIN : Jurnal Ilmiah Kebidanan
Publisher : Prodi D III Kebidanan Fakultas Ilmu Kesehatan Universitas Ibrahimy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35316/oksitosin.v13i1.8065

Adolescence is a critical period marked by rapid physical and psychological changes that contribute to the formation of body image, which may influence health-related behaviors such as dietary habits and nutritional status. This study aimed to examine the relationship between body image perception, dietary habits, and hemoglobin levels among adolescent girls. An analytical observational study with a cross-sectional design was conducted involving 70 tenth-grade female students at Public Vocational School 3 Malang. Body image was assessed using the Multidimensional Body-Self Relations Questionnaire–Appearance Scale (MBSRQ-AS), while dietary habits were evaluated using the Adolescent Food Habits Checklist (AFHC). Hemoglobin levels were measured using standard procedures. Pearson correlation analysis showed a significant relationship between body image perception and dietary habits (p = 0.046; r = 0.24), whereas no significant association was found between body image perception and hemoglobin levels (p = 0.983). These findings indicate that adolescent girls with a more positive body image tend to adopt healthier eating habits, although body image does not directly influence hemoglobin levels. The results suggest that school-based nutrition programs should incorporate body image education as part of adolescent health promotion to encourage healthy dietary behaviors, which may indirectly support optimal nutritional status.

Analysis of Total Flavonoid and Phenol Content from the Combination of Red Spinach (Amaranthus tricolor L.) Ethanolic Extract and Chrysanthemum Flower (Chrysanthemum morifolium) Ethanolic Extract as a Potential Anti-anemic Kusbandiyah, Jiarti; Angelia Puspadewi, Yuniar; Oktia Maghfiroh, Dinda
Jurnal Pendidikan Keperawatan Indonesia Vol 9, No 1 (2023): Volume 9, Nomor 1, Juni 2023
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/jpki.v9i1.58209

Red spinach and chrysanthemum are two plants that contain various active compounds, including flavonoids and phenols which have good antioxidant activity. One of the benefits of antioxidants is as an anti-anemia. The combination of red spinach and chrysanthemum extracts is expected to be a potential alternative treatment for anemia by combining high Fe and antioxidants found in both herbal ingredients. Research related to test the levels of flavonoids and phenols in red spinach and chrysanthemum extracts (in combination) has not been carried out. This study aimed to measure the total flavonoid and phenol levels of the combination of red spinach ethanol extract (EEBM) and chrysanthemum flower ethanol extract (EEBK). The design of this research is descriptif quantitative. The method used for the extraction is maceration. The solvent used is 70% ethanol. Then the two extracts were combined by mixing the two extracts with a ratio of 5.6 ml EEBM and 1.4 ml EEBK. The process of mixing the extracts was carried out by the centrifugation method. The suspension of the combination of EEBM and EEBK was then measured for the total flavonoid and phenol content. Determination of total flavonoid content (TFC) was carried out using UV-Vis spectrophotometry method with AlCl3 reagent at 425 nm. TFC results are expressed in quercetin equivalent (QE). The TFC result from the combination of EEBM and EEBK was 85.33 mg QE/g. Determination of total phenol content (TPC) was carried out using UV-Vis spectrophotometry method with Folin-Ciocalteu LP reagent at 735 nm. TPC results are expressed in gallic acid equivalent (GAE). The TPC result from the combination of EEBM and EEBK is 25.22 GAE/g. Flavonoids and phenols contained in the combination of EEBM + EEBK extracts can be an alternative anti-anemia because they have the effect of helping the absorption of iron in the intestine

Hubungan Pola Menstruasi dan Status Gizi Berdasarkan Indeks Massa Tubuh dengan Kadar Hemoglobin pada Remaja Putri Dinda Oktia Maghfiroh; Sabatina Windyaningrum; Dellis Eka Mutiasari; Naila Farihatul Itsnainy
Malahayati Nursing Journal Vol 8, No 3 (2026): Volume 8 Nomor 3 (2026)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v8i3.24510

ABSTRACT Adolescence is a phase of life that carries a high risk of anemia, particularly iron deficiency anemia, influenced by increased nutrient requirements during growth and blood loss due to menstruation. Menstrual patterns and nutritional status (BMI/Age) are factors suspected of contributing to variations in hemoglobin levels in this age group. This study aimed to analyze the relationship between menstrual patterns and nutritional status based on body mass index and hemoglobin levels in adolescent girls. The study used an observational analytical design with a cross-sectional approach. A total of 70 adolescent girls from SMKN 3 Malang were recruited as respondents using a purposive sampling method. Data on menstrual patterns were obtained through questionnaires, while nutritional status (BMI/Age) and hemoglobin levels were measured directly. Data analysis included univariate and bivariate analyses (Pearson and Chi-Square test). The Pearson analysis showed a significant relationship between menstrual patterns and hemoglobin levels (p=0.035), with respondents with irregular menstrual patterns tending to have lower hemoglobin levels. In contrast, body mass index did not show a significant association with hemoglobin levels using the Chi-Square test (p=0.642). Adolescents with irregular menstrual patterns tend to have a higher risk of anemia compared to those with regular menstrual patterns. Meanwhile, nutritional status (BMI/Age) is not a major factor influencing hemoglobin levels in this population and does not necessarily reflect micronutrient adequacy, particularly iron. Keywords: Adolescent Girls, Menstrual Patterns, Nutritional Status, Hemoglobin, Anemia. ABSTRAK Masa remaja putri merupakan fase kehidupan yang memiliki risiko tinggi terhadap terjadinya anemia, khususnya anemia defisiensi besi, yang dipengaruhi oleh peningkatan kebutuhan zat gizi selama pertumbuhan serta kehilangan darah akibat menstruasi. Pola menstruasi dan status gizi (IMT/U) merupakan faktor yang diduga berkontribusi terhadap variasi kadar hemoglobin pada kelompok usia ini. Penelitian ini bertujuan untuk menganalisis hubungan antara pola menstruasi dan status gizi berdasarkan indeks massa tubuh dengan kadar hemoglobin pada remaja putri. Penelitian dilakukan menggunakan desain observasional analitik dengan pendekatan cross-sectional. Sebanyak 70 remaja putri SMKN 3 Malang dilibatkan sebagai responden dengan metode purposive sampling. Data mengenai pola menstruasi diperoleh melalui kuesioner, sedangkan status gizi (IMT/U) dan kadar hemoglobin diukur secara langsung. Analisis data meliputi analisis univariat dan bivariat (uji Pearson dan Chi-Square). Hasil analisis Pearson menunjukkan bahwa pola menstruasi memiliki hubungan yang signifikan dengan kadar hemoglobin (p=0,035), di mana responden dengan pola menstruasi tidak normal cenderung memiliki kadar hemoglobin yang lebih rendah. Sebaliknya, indeks massa tubuh tidak menunjukkan hubungan yang bermakna dengan kadar hemoglobin melalui uji Chi-Square (p=0,642). Remaja dengan pola menstruasi tidak teratur cenderung memiliki risiko anemia yang lebih tinggi dibandingkan dengan mereka yang memiliki pola menstruasi teratur. Sementara status gizi (IMT/U) bukan merupakan faktor utama yang memengaruhi kadar hemoglobin pada populasi ini dan belum tentu mencerminkan kecukupan mikronutrien, khususnya zat besi. Kata Kunci: Remaja Putri, Pola Menstruasi, Status Gizi, Hemoglobin, Anemia.

POTENSI PROPOLIS Trigona sp. TERHADAP JAMUR PENYEBAB KANDIDIASIS VULVOVAGINAL Dinda Oktia Maghfiroh
Media Husada Journal of Midwifery Science Vol. 3 No. 1 (2025): Januari
Publisher : LPPM Widyagama Husada Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/mhjms.v3i1.19

Vulvovaginal candidiasis is a vulvar and/or intravaginal infection that often attacks women of reproductive age. The most common cause of this infection is Candida albicans. C. albicans has a high ability to form biofilm. Biofilm is a virulence form of C. albicans and a major cause of antifungal drugs resistance. One alternative that can be used is propolis. Propolis is a wax mixed with resin produced by honey bees as a result of a collection of substances released by plants. The type of bee that produces the most propolis is Trigona sp. This review aims to describe a comprehensive overview of the potential of Trigona sp. propolis against fungi that cause vulvovaginal candidiasis, especially C. albicans. The research method is a literature review with data sources in the form of true experimental research articles from both national and international journals via Google Scholar, PubMed, Elsevier, and Researchgate. Literature studies show that propolis Trigona sp. from several regions in Indonesia, Nepal and Malaysia is known to contain flavonoid compounds which have antifungals and antibiofilms potential against C. albicans (major cause of vulvovaginal candidiasis).

The Effect of Growth and Development Stimulation on the Development of Infants with Cancer Aged 1–3 Years (Toddlers) Fifit Kustiani Kustiani; Wenny Rahmawati Rahmawati; Dinda Oktia Maghfiroh Maghfiroh
Media Husada Journal of Midwifery Science Vol. 3 No. 2 (2025): Juli
Publisher : LPPM Widyagama Husada Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/mhjms.v3i2.24

Abstract The growth and development of children aged 1–3 years (toddlers) suffering from cancer often face obstacles due to the impact of the disease and the therapies undergone, such as chemotherapy and radiation. Developmental delays can affect children's motor, cognitive, language, and social aspects. Providing growth and development stimulation is one intervention that can help optimize child development under these conditions. This study aims to analyze the effect of growth and development stimulation on the development of toddlers with cancer. This study used a pre-experimental method with a One-Group Pre-Post Test Design approach. The sampling technique used was non-probability sampling with purposive sampling. Data collection was conducted through observations of children's development before and after the intervention of growth and development stimulation. Data analysis was performed using the Wilcoxon Sign Rank Test to examine differences in development before and after stimulation. The statistical test results showed a p-value of 0.000, indicating a significant effect of growth and development stimulation on the development of children aged 1–3 years with cancer. This study concludes that growth and development stimulation plays a crucial role in improving the development of children experiencing delays due to cancer. Therefore, it is recommended that healthcare professionals and parents provide appropriate and continuous stimulation to support optimal child growth and development. Abstrak Pertumbuhan dan perkembangan anak usia 1–3 tahun (batita) yang menderita kanker sering mengalami hambatan akibat dampak penyakit dan terapi yang dijalani, seperti kemoterapi dan radiasi. Keterlambatan perkembangan dapat berpengaruh pada aspek motorik, kognitif, bahasa, dan sosial anak. Pemberian stimulasi tumbuh kembang menjadi salah satu intervensi yang dapat membantu mengoptimalkan perkembangan anak dalam kondisi tersebut. Penelitian ini bertujuan untuk menganalisis pengaruh pemberian stimulasi tumbuh kembang terhadap perkembangan batita yang menderita kanker. Penelitian ini menggunakan metode pra-eksperimental dengan pendekatan One Group Pre-Post Test Design. Teknik sampling yang digunakan adalah non-probability sampling dengan jenis purposive sampling. Pengumpulan data dilakukan dengan observasi perkembangan anak sebelum dan sesudah intervensi stimulasi tumbuh kembang. Sampel yang digunakan pada penelitian ini adalah 30 batita yang menderita kanker di Ruang Tondano RSUD dr. Saiful Anwar Malang. Analisis data menggunakan Wilcoxon Sign Rank Test untuk menguji perbedaan perkembangan sebelum dan sesudah pemberian stimulasi. Hasil uji statistik menunjukkan nilai p = 0,000 yang berarti terdapat pengaruh yang signifikan dari pemberian stimulasi tumbuh kembang terhadap perkembangan anak usia 1–3 tahun yang menderita kanker. Dari penelitian ini dapat disimpulkan penelitian bahwa stimulasi tumbuh kembang memiliki peran penting dalam membantu meningkatkan perkembangan anak yang mengalami keterlambatan akibat kanker, terutama yang menjalani kemoterapi. Oleh karena itu, disarankan agar tenaga kesehatan dan orang tua memberikan stimulasi yang sesuai dan berkelanjutan guna mendukung pertumbuhan serta perkembangan anak dalam kondisi yang optimal.

The Relationship Between Family Support and Dietary Adherence Among Mothers with Gestational Diabetes Mellitus Jefrich nurpastikaningrum; Jiarti Kusbandiyah; Dinda Oktia Maghfiroh
Media Husada Journal of Midwifery Science Vol. 4 No. 1 (2026): Januari
Publisher : LPPM Widyagama Husada Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/mhjms.v4i1.36

Dietary compliance in mothers with Gestational Diabetes Mellitus (GDM) is an important aspect in controlling blood glucose levels during pregnancy to reduce the risk of complications. Family support plays an important role in improving dietary compliance in GDM mothers. This study aims to determine the relationship between family support and dietary compliance in GDM mothers at Dr. Saiful Anwar General Hospital, Malang City. This study used an observational analytical method with a cross-sectional design. Data collection was conducted from October to November 2024 at Dr. Saiful Anwar General Hospital, Malang City, with 96 respondents selected using non-probability sampling techniques according to inclusion and exclusion criteria. Data were collected through a family support questionnaire and a GDM mother's dietary compliance questionnaire. Data analysis used the Spearman rank test. Based on the results of the Spearman Rank test, a significant relationship was found between family support and GDM mother's dietary compliance (p-value = 0.000 p 0.05) with a very strong relationship strength (r = 0.998). Thus, H was rejected and H was accepted. It can be concluded that there is a significant relationship between family support and dietary compliance in mothers with gestational diabetes mellitus (GDM) at Dr. Saiful Anwar Regional General Hospital in Malang City. High levels of family support can increase maternal motivation and compliance in undergoing diet therapy.

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