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All Journal Medical Journal of Indonesia Indonesian Journal of Cancer Jurnal Penyakit Dalam Indonesia
Zubairi Djoerban
Divisi Hematologi-Onkologi Medik, Departemen Ilmu Penyakit Dalam, FKUI/RSUPN dr. Cipto Mangunkusumo, Jakarta, Indonesia
Health Professions Medicine & Pharmacology

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Journal : Medical Journal of Indonesia

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Viral load profiles in drug users with asymptomatic HIV infection and normal CD4 cell counts Djoerban, Zubairi
Medical Journal of Indonesia Vol 11, No 3 (2002): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (164.047 KB) | DOI: 10.13181/mji.v11i3.68

Abstract

Since the year 2000 there has been a steep increased in the number of HIV/AIDS patients in Indonesia, coming mostly from intravenous drug users. Antiretroviral treatment has been proved to decrease mortality and increase quality of life of HIV/AIDS patients. The treatment is given according to clinical condition of the patients, number of CD4 and viral load. In this study, CD4 and viral load were examined in 71 asymptomatic HIV patients originated from injecting-drug users. CD4 counting was performed by indirect immunoflouresence method using monoclonal antibody, and viral load was tested using PCR technique. Among 56 patients who has the number of CD4 more than 200/mm3, 30 patients (55.4 %) has viral load more than 55,000 copies/ml and 35.7% has viral load 5,000-55,000 copies/ml. Correlation between the number of CD4 and viral load gave the r value of 0.194. It is concluded that there is no association between the number of CD4 and viral load in drug user HIV/AIDS patients. The treatment of HIV/AIDS for these patients should be given according to the viral load. (Med J Indones 2002; 11: 143-7)Keywords: viral load, CD4, injecting-drug user
Breast-conserving treatment versus mastectomy in T1-2N0 breast cancer: which one is better for Indonesian women? Nugroho, Rafiq S.; Soediro, Ratnawati; Siregar, Nuryati C.; Djoerban, Zubairi; Poetiray, Evert D.C.; Gondhowiardjo, Soehartati
Medical Journal of Indonesia Vol 21, No 4 (2012): November
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (444.811 KB) | DOI: 10.13181/mji.v21i4.508

Abstract

Background: This study aimed to compare the treatment outcomes between the use of breast-conserving treatment (BCT) and mastectomy for T1-2N0 breast cancer patients.Methods: This study retrospectively reviewed T1-2N0 breast cancer patients who received treatment between January 2001 and December 2010 at Department of Radiotherapy Cipto Mangunkusumo Hospital and Jakarta Breast Center. The endpoints of this study were overall survival (OS), local  recurrence (LR), contra-lateral breast cancer (CBC), distant metastasis (DM), and disease-free survival (DFS).Results: Among the 262 eligible patients, 200 (76.3%) patients underwent BCT while 62 (23.7%) patients underwent mastectomy. There were no differences between BCT and mastectomy groups in 5-Y OS (88.2% vs 86.7%, p = 0,743), LR (7.4% vs 2.7%, p = 0.85), CBC (3.4% vs 5.3%, p = 0.906), DM (17.7% vs 37.7%, p = 0.212), and DFS (78.5% vs 60.7%, p = 0.163). In multivariate analysis, grade 3 was associated with worse OS (HR 2.79; 95% CI 1.08 – 7.21, p = 0.03) and DFS (HR 2.32; 95% CI 1.06 – 5.06). Premenopausal women were associated with decreased risk of DM (HR 0.37; 95% CI 0.17 – 0.80) and DFS (HR 0.38; 95% CI 0.19 – 0.78).Conclusion: BCT and mastectomy showed similar outcome in terms of OS, LR, CBC, DM, and DFS. (Med J Indones. 2012;21:220-4)Keywords: Breast-conserving treatment, mastectomy, outcomes
Co-Authors Abidin Widjanarko Anna M Lubis, Anna M Aru W. Sudoyo Arwin A.P. Akip, Arwin A.P. Asrul Harsal, Asrul Bambang Karsono Budi Utomo Daldiyono Daldiyono Djumhana Atmakusuma, Djumhana Dody Ranuhardy, Dody E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Erni J Nelwan, Erni J Evert D.C. Poetiray Evy Yunihastuti H.M. Sjaifoellah Noer Harryanto Reksodiputro, Harryanto HILMAN TADJOEDIN, HILMAN Irwanto Irwanto Iwan Iwan Julius R Samban Karmel L. Tambunan Ken Ayu Mastini, Ken Ayu Laurentius A Pramono, Laurentius A Murdani Abdullah Nanda N. Muhammad, Nanda N. Noorwati S -, Noorwati S Nugroho Prayogo Nuryati C. Siregar R Irawati Ismail, R Irawati Rafiq S. Nugroho Ratnawati Soediro Rino A Gani Ronald Hukom Sabarinah Sabarinah, Sabarinah Shufrie Effendi, Shufrie Soehartati Gondhowiardjo Surilena Hasan Syafrizal Syafei, Syafrizal Unggul Budihusodo Zakifman Jack, Zakifman